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Volumn 6, Issue 5, 2014, Pages 614-624

Serum metabolomic profiles suggest influence of sex and oral contraceptive use

Author keywords

Acylcarnitines; Amino acids; Carnitine; Metabolomics; Oral contraceptives; Sex

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARAGINE; ASPARTATE AMINOTRANSFERASE; CITRULLINE; ETHINYLESTRADIOL; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; GESTAGEN; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HISTIDINE; HYDROXYPROLINE; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; ORNITHINE; PROLINE; TRIACYLGLYCEROL; TYROSINE; VALINE;

EID: 84908068717     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (58)

References (55)
  • 2
    • 80054920376 scopus 로고    scopus 로고
    • A GENS-based approach to cardiovascular pharmacology: Impact on metabolism, pharmacokinetics and pharmacodynamics
    • Franconi F, Carru C, Spoletini I, Malorni W, Vella S, Mercuro G, Deidda M and Rosano G. A GENS-based approach to cardiovascular pharmacology: impact on metabolism, pharmacokinetics and pharmacodynamics. Ther Deliv 2011; 2: 1437-1453.
    • (2011) Ther Deliv , vol.2 , pp. 1437-1453
    • Franconi, F.1    Carru, C.2    Spoletini, I.3    Malorni, W.4    Vella, S.5    Mercuro, G.6    Deidda, M.7    Rosano, G.8
  • 4
    • 0028875935 scopus 로고
    • Acylcarnitines in intermediary metabolism
    • Sewell AC and Bohles HJ. Acylcarnitines in intermediary metabolism. Eur J Pediatr 1995; 154: 871-877.
    • (1995) Eur J Pediatr , vol.154 , pp. 871-877
    • Sewell, A.C.1    Bohles, H.J.2
  • 5
    • 4444315751 scopus 로고    scopus 로고
    • Carnitine: A nutritional, biosynthetic, and functional perspective
    • Steiber A, Kerner J and Hoppel CL. Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med 2004; 25: 455-473.
    • (2004) Mol Aspects Med , vol.25 , pp. 455-473
    • Steiber, A.1    Kerner, J.2    Hoppel, C.L.3
  • 7
    • 55949117892 scopus 로고    scopus 로고
    • Determination of the reference range of endogenous plasma carnitines in healthy adults
    • Reuter SE, Evans AM, Chace DH and Fornasini G. Determination of the reference range of endogenous plasma carnitines in healthy adults. Ann Clin Biochem 2008; 45: 585-592.
    • (2008) Ann Clin Biochem , vol.45 , pp. 585-592
    • Reuter, S.E.1    Evans, A.M.2    Chace, D.H.3    Fornasini, G.4
  • 8
    • 0036471216 scopus 로고    scopus 로고
    • Carnitine biosynthesis in mammals
    • Vaz FM and Wanders RJ. Carnitine biosynthesis in mammals. Biochem J 2002; 361: 417-429.
    • (2002) Biochem J , vol.361 , pp. 417-429
    • Vaz, F.M.1    Wanders, R.J.2
  • 9
    • 0035823607 scopus 로고    scopus 로고
    • Molecular and biochemical characterization of rat epsilon -N-trimethyllysine hydroxylase, the first enzyme of carnitine biosynthesis
    • Vaz FM, Ofman R, Westinga K, Back JW and Wanders RJ. Molecular and biochemical characterization of rat epsilon -N-trimethyllysine hydroxylase, the first enzyme of carnitine biosynthesis. J Biol Chem 2001; 276: 33512-33517.
    • (2001) J Biol Chem , vol.276 , pp. 33512-33517
    • Vaz, F.M.1    Ofman, R.2    Westinga, K.3    Back, J.W.4    Wanders, R.J.5
  • 10
    • 0014962556 scopus 로고
    • Cofactor requirements of gamma-butyrobetaine hydroxylase from rat liver
    • Lindstedt G and Lindstedt S. Cofactor requirements of gamma-butyrobetaine hydroxylase from rat liver. J Biol Chem 1970; 245: 4178-4186.
    • (1970) J Biol Chem , vol.245 , pp. 4178-4186
    • Lindstedt, G.1    Lindstedt, S.2
  • 11
    • 44949175928 scopus 로고    scopus 로고
    • Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome
    • Fenkci SM, Fenkci V, Oztekin O, Rota S and Karagenc N. Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome. Hum Reprod 2008; 23: 1602-1606.
    • (2008) Hum Reprod , vol.23 , pp. 1602-1606
    • Fenkci, S.M.1    Fenkci, V.2    Oztekin, O.3    Rota, S.4    Karagenc, N.5
  • 12
    • 0022498810 scopus 로고
    • Plasma carnitine and renal-carnitine clearance during pregnancy
    • Cederblad G, Fahraeus L and Lindgren K. Plasma carnitine and renal-carnitine clearance during pregnancy. Am J Clin Nutr 1986; 44: 379-383.
    • (1986) Am J Clin Nutr , vol.44 , pp. 379-383
    • Cederblad, G.1    Fahraeus, L.2    Lindgren, K.3
  • 13
    • 70249093588 scopus 로고    scopus 로고
    • Carnitine status of pregnant women: Effect of carnitine supplementation and correlation between iron status and plasma carnitine concentration
    • Keller U, van der Wal C, Seliger G, Scheler C, Ropke F and Eder K. Carnitine status of pregnant women: effect of carnitine supplementation and correlation between iron status and plasma carnitine concentration. Eur J Clin Nutr 2009; 63: 1098-1105.
    • (2009) Eur J Clin Nutr , vol.63 , pp. 1098-1105
    • Keller, U.1    Van Der Wal, C.2    Seliger, G.3    Scheler, C.4    Ropke, F.5    Eder, K.6
  • 14
    • 77951112808 scopus 로고    scopus 로고
    • Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women
    • Ringseis R, Hanisch N, Seliger G and Eder K. Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women. BMC Pregnancy Childbirth 2010; 10: 17.
    • (2010) BMC Pregnancy Childbirth , vol.10
    • Ringseis, R.1    Hanisch, N.2    Seliger, G.3    Eder, K.4
  • 15
    • 0015606262 scopus 로고
    • study of plasma free amino acid levels. II. Normal values for children and adults
    • Armstrong MD and Stave U. A study of plasma free amino acid levels. II. Normal values for children and adults. Metabolism 1973; 22: 561-569.
    • (1973) Metabolism , vol.22 , pp. 561-569
    • Armstrong, M.D.1    Stave, U.A.2
  • 16
    • 0025853254 scopus 로고
    • Plasma amino acid concentrations in healthy elderly men and women
    • Caballero B, Gleason RE and Wurtman RJ. Plasma amino acid concentrations in healthy elderly men and women. Am J Clin Nutr 1991; 53: 1249-1252.
    • (1991) Am J Clin Nutr , vol.53 , pp. 1249-1252
    • Caballero, B.1    Gleason, R.E.2    Wurtman, R.J.3
  • 17
    • 0019497429 scopus 로고
    • Effect of oral contraceptives on tryptophan and tyrosine availability: Evidence for a possible contribution to mental depression
    • Moller SE. Effect of oral contraceptives on tryptophan and tyrosine availability: evidence for a possible contribution to mental depression. Neuropsychobiology 1981; 7: 192-200.
    • (1981) Neuropsychobiology , vol.7 , pp. 192-200
    • Moller, S.E.1
  • 20
    • 0017132622 scopus 로고
    • Effect of oral contraceptives and vitamin B6 supplements on alanine and glycine metabolism
    • Rose DP, Leklem JE, Brown RR and Potera C. Effect of oral contraceptives and vitamin B6 supplements on alanine and glycine metabolism. Am J Clin Nutr 1976; 29: 956-960.
    • (1976) Am J Clin Nutr , vol.29 , pp. 956-960
    • Rose, D.P.1    Leklem, J.E.2    Brown, R.R.3    Potera, C.4
  • 21
    • 84908064937 scopus 로고    scopus 로고
    • Estrogens and Progestins. In: Brunton L, Chabner B, Knollmann B, editors. Goodman & Gilman’s The Pharmacological Basis of The-rapeutics, manca l’anno
    • Estrogens and Progestins. In: Brunton L, Chabner B, Knollmann B, editors. Goodman & Gilman’s The Pharmacological Basis of The-rapeutics. pp. 12. manca l’anno.
  • 23
    • 0025129387 scopus 로고
    • Tandem mass spectrometry: A new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism
    • Millington DS, Kodo N, Norwood DL and Roe CR. Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism. J Inherit Metab Dis 1990; 13: 321-324.
    • (1990) J Inherit Metab Dis , vol.13 , pp. 321-324
    • Millington, D.S.1    Kodo, N.2    Norwood, D.L.3    Roe, C.R.4
  • 24
    • 0001222859 scopus 로고
    • The analysis of diagnostic markers of genetic disorders to human blood and urine using tandem mass spectrometry with liquid secondary ion mass spectrometry
    • Millington D, Kodo N, Terada N, Roe D and Chase D. The analysis of diagnostic markers of genetic disorders to human blood and urine using tandem mass spectrometry with liquid secondary ion mass spectrometry. Int J Mass Spectrom Ion Proc 1991; 111: 211-228.
    • (1991) Int J Mass Spectrom Ion Proc , vol.111 , pp. 211-228
    • Millington, D.1    Kodo, N.2    Terada, N.3    Roe, D.4    Chase, D.5
  • 26
    • 0020054144 scopus 로고
    • Rapid assay for amino acids in serum or urine by pre-column derivatization and reversed-phase liquid chromatography
    • Turnell DC and Cooper JD. Rapid assay for amino acids in serum or urine by pre-column derivatization and reversed-phase liquid chromatography. Clin Chem 1982; 28: 527-531.
    • (1982) Clin Chem , vol.28 , pp. 527-531
    • Turnell, D.C.1    Cooper, J.D.2
  • 27
    • 0023684172 scopus 로고
    • Determination of amino acids in biological, pharmaceutical, plant and food samples by automated precolumn derivatization and high-performance liquid chromatography
    • Schuster R. Determination of amino acids in biological, pharmaceutical, plant and food samples by automated precolumn derivatization and high-performance liquid chromatography. J Chromatogr 1988; 431: 271-284.
    • (1988) J Chromatogr , vol.431 , pp. 271-284
    • Schuster, R.1
  • 28
    • 0023740483 scopus 로고
    • Ion-exchange chromatography and clinical criteria in the screening of the aminoacidopathies
    • Parvy PR, Bardet JI, Rabier DM, Saudubray JM and Kamoun PP. Ion-exchange chromatography and clinical criteria in the screening of the aminoacidopathies. Clin Chim Acta 1988; 176: 269-277.
    • (1988) Clin Chim Acta , vol.176 , pp. 269-277
    • Parvy, P.R.1    Bardet, J.I.2    Rabier, D.M.3    Saudubray, J.M.4    Kamoun, P.P.5
  • 29
    • 57649176607 scopus 로고    scopus 로고
    • Quality of analytical performance in inherited metabolic disorders: The role of ERNDIM
    • Fowler B, Burlina A, Kozich V and Vianey-Saban C. Quality of analytical performance in inherited metabolic disorders: the role of ERNDIM. J Inherit Metab Dis 2008; 31: 680-689.
    • (2008) J Inherit Metab Dis , vol.31 , pp. 680-689
    • Fowler, B.1    Burlina, A.2    Kozich, V.3    Vianey-Saban, C.4
  • 30
    • 33751219573 scopus 로고    scopus 로고
    • Serum amino acids as indicators of cerebrospinal neuronal activity in patients with micturition disorders
    • Nishijima S, Sugaya K, Fukuda T, Miyazato M, Ashimine S and Ogawa Y. Serum amino acids as indicators of cerebrospinal neuronal activity in patients with micturition disorders. Int J Urol 2006; 13: 1479-1483.
    • (2006) Int J Urol , vol.13 , pp. 1479-1483
    • Nishijima, S.1    Sugaya, K.2    Fukuda, T.3    Miyazato, M.4    Ashimine, S.5    Ogawa, Y.6
  • 34
    • 0034936583 scopus 로고    scopus 로고
    • Gender related differences in the effect of aging on blood amino acid compartmentation
    • Proenza AM, Crespi C, Roca P and Palou A. Gender related differences in the effect of aging on blood amino acid compartmentation. J Nutr Biochem 2001; 12: 431-440.
    • (2001) J Nutr Biochem , vol.12 , pp. 431-440
    • Proenza, A.M.1    Crespi, C.2    Roca, P.3    Palou, A.4
  • 35
    • 0030357975 scopus 로고    scopus 로고
    • Effects of oral contraceptives on plasma neutral amino acids and cholesterol during a menstrual cycle
    • Moller SE, Moller BM, Olesen M and Fjalland B. Effects of oral contraceptives on plasma neutral amino acids and cholesterol during a menstrual cycle. Eur J Clin Pharmacol 1996; 50: 179-184.
    • (1996) Eur J Clin Pharmacol , vol.50 , pp. 179-184
    • Moller, S.E.1    Moller, B.M.2    Olesen, M.3    Fjalland, B.4
  • 37
    • 0041421022 scopus 로고    scopus 로고
    • Gender differences in the regulation of amino acid metabolism
    • Lamont LS, McCullough AJ and Kalhan SC. Gender differences in the regulation of amino acid metabolism. J Appl Physiol 2003; 95: 1259-1265.
    • (2003) J Appl Physiol , vol.95 , pp. 1259-1265
    • Lamont, L.S.1    McCullough, A.J.2    Kalhan, S.C.3
  • 39
    • 0017279502 scopus 로고
    • Plasma carnitine and body composition
    • Cederblad G. Plasma carnitine and body composition. Clin Chim Acta 1976; 67: 207-212.
    • (1976) Clin Chim Acta , vol.67 , pp. 207-212
    • Cederblad, G.1
  • 40
    • 0023488430 scopus 로고
    • Plasma carnitine compartment and red blood cell carnitine compartment of healthy adults
    • Borum PR. Plasma carnitine compartment and red blood cell carnitine compartment of healthy adults. Am J Clin Nutr 1987; 46: 437-441.
    • (1987) Am J Clin Nutr , vol.46 , pp. 437-441
    • Borum, P.R.1
  • 41
    • 0031935711 scopus 로고    scopus 로고
    • Age-and sex-related differences of serum carnitine in a Japanese population
    • Takiyama N and Matsumoto K. Age-and sex-related differences of serum carnitine in a Japanese population. J Am Coll Nutr 1998; 17: 71-74.
    • (1998) J Am Coll Nutr , vol.17 , pp. 71-74
    • Takiyama, N.1    Matsumoto, K.2
  • 43
    • 84882966654 scopus 로고    scopus 로고
    • Regular cigarette smoking influences the transsulfuration pathway, endothelial function, and inflammation biomarkers in a sex-gender specific manner in healthy young humans
    • Campesi I, Carru C, Zinellu A, Occhioni S, Sanna M, Palermo M, Tonolo G, Mercuro G and Franconi F. Regular cigarette smoking influences the transsulfuration pathway, endothelial function, and inflammation biomarkers in a sex-gender specific manner in healthy young humans. Am J Transl Res 2013; 5: 497-509.
    • (2013) Am J Transl Res , vol.5 , pp. 497-509
    • Campesi, I.1    Carru, C.2    Zinellu, A.3    Occhioni, S.4    Sanna, M.5    Palermo, M.6    Tonolo, G.7    Mercuro, G.8    Franconi, F.9
  • 45
    • 0035021014 scopus 로고    scopus 로고
    • Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass
    • Lango R, Smolenski RT, Narkiewicz M, Suchorzewska J and Lysiak-Szydlowska W. Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass. Cardiovasc Res 2001; 51: 21-29.
    • (2001) Cardiovasc Res , vol.51 , pp. 21-29
    • Lango, R.1    Smolenski, R.T.2    Narkiewicz, M.3    Suchorzewska, J.4    Lysiak-Szydlowska, W.5
  • 46
    • 84866294498 scopus 로고    scopus 로고
    • Systemic primary carnitine deficiency: An overview of clinical manifestations, diagnosis, and management
    • Magoulas PL and El-Hattab AW. Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management. Orphanet J Rare Dis 2012; 7: 68.
    • (2012) Orphanet J Rare Dis , vol.7
    • Magoulas, P.L.1    El-Hattab, A.W.2
  • 48
    • 84872688669 scopus 로고    scopus 로고
    • Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22-a21)
    • Tamai I. Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22-a21). Biopharm Drug Dispos 2013; 34: 29-44.
    • (2013) Biopharm Drug Dispos , vol.34 , pp. 29-44
  • 49
    • 0027319784 scopus 로고
    • Serum carnitine concentrations in coeliac disease
    • Lerner A, Gruener N and Iancu TC. Serum carnitine concentrations in coeliac disease. Gut 1993; 34: 933-935.
    • (1993) Gut , vol.34 , pp. 933-935
    • Lerner, A.1    Gruener, N.2    Iancu, T.C.3
  • 50
    • 84880582555 scopus 로고    scopus 로고
    • Carnitine and acylcarnitine profiles in dried blood spots of patients with acute myocardial infarction
    • Khan HA, Alhomida AS, Madani HA and Sobki SH. Carnitine and acylcarnitine profiles in dried blood spots of patients with acute myocardial infarction. Metabolomics 2013; 9: 828-838.
    • (2013) Metabolomics , vol.9 , pp. 828-838
    • Khan, H.A.1    Alhomida, A.S.2    Madani, H.A.3    Sobki, S.H.4
  • 51
    • 0029894774 scopus 로고    scopus 로고
    • Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: Metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool
    • Ford DA, Han X, Horner CC and Gross RW. Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool. Biochemistry 1996; 35: 7903-7909.
    • (1996) Biochemistry , vol.35 , pp. 7903-7909
    • Ford, D.A.1    Han, X.2    Horner, C.C.3    Gross, R.W.4
  • 52
    • 0025364196 scopus 로고
    • Defective myocardial carnitine metabolism in congestive heart failure secondary to dilated cardiomyopathy and to coronary, hypertensive and valvular heart diseases
    • Regitz V, Shug AL and Fleck E. Defective myocardial carnitine metabolism in congestive heart failure secondary to dilated cardiomyopathy and to coronary, hypertensive and valvular heart diseases. Am J Cardiol 1990; 65: 755-760.
    • (1990) Am J Cardiol , vol.65 , pp. 755-760
    • Regitz, V.1    Shug, A.L.2    Fleck, E.3
  • 55
    • 0035666654 scopus 로고    scopus 로고
    • Do women have more adverse drug reactions?
    • Rademaker M. Do women have more adverse drug reactions? Am J Clin Dermatol 2001; 2: 349-351.
    • (2001) Am J Clin Dermatol , vol.2 , pp. 349-351
    • Rademaker, M.1


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