Asymmetric synthesis of highly functionalized tetrahydropyran DPP-4 inhibitor

Organic Letters

Volumn 16, Issue 20, 2014, Pages 5422-5425

  Xu, Feng ^a   Zacuto, Michael J ^a   Kohmura, Yoshinori ^a   Rosen, Jon ^a   Gibb, Andrew ^b   Alam, Mahbub ^b   Scott, Jeremy ^b   Tschaen, David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; GLYCINE; PYRONE DERIVATIVE; RUTHENIUM;

AMINATION; ANALOGS AND DERIVATIVES; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

AMINATION; CATALYSIS; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; ENZYME INHIBITORS; GLYCINE; HYPOGLYCEMIC AGENTS; KINETICS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PYRONES; RUTHENIUM; STEREOISOMERISM;

EID: 84908060768     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol502661g     Document Type: Article

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