Constitutive activation of CaMKKα signaling is sufficient but not necessary for mTORC1 activation and growth in mouse skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 307, Issue 8, 2014, Pages E686-E694

  Ferey, Jeremie L A ^a   Brault, Jeffrey J ^a   Smith, Cheryl A S ^a   Witczak, Carol A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Calcium; Kinase; Protein degradation; Protein synthesis; Synergist ablation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHENYLALANINE; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG; CAMKK1 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; MUSCLE PROTEIN; PROTEIN KINASE INHIBITOR; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ELECTROPORATION; FEMALE; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MOUSE; MUSCLE GROWTH; MUSCLE HYPERTROPHY; MUSCLE MASS; NONHUMAN; PROTEIN CONTENT; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SKELETAL MUSCLE; ABLATION THERAPY; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CALCIUM SIGNALING; CHEMISTRY; CROSS BREEDING; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HYPERTROPHY; IN VITRO STUDY; METABOLISM; MUSCLE DEVELOPMENT; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING; UPREGULATION;

ABLATION TECHNIQUES; ANIMALS; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CROSSES, GENETIC; FEMALE; GENE EXPRESSION REGULATION; HYPERTROPHY; IN VITRO TECHNIQUES; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; MUSCLE DEVELOPMENT; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TOR SERINE-THREONINE KINASES; UP-REGULATION;

EID: 84908052787     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00322.2014     Document Type: Article

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