Cardiac molecular imaging

Seminars in Nuclear Medicine

Volumn 44, Issue 5, 2014, Pages 386-397

  Wollenweber, Tim ^a   Bengel, Frank M ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 13;

ADRENERGIC SYSTEM; ANGIOGENESIS; APOPTOSIS; ARTICLE; AUTONOMIC INNERVATION; CARDIAC IMAGING; CELL TRACKING; CLINICAL PRACTICE; EXTRACELLULAR MATRIX; HEART; HEART DISEASE; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE REMODELING; HEART MUSCLE METABOLISM; HEART VENTRICLE REMODELING; HUMAN; MOLECULAR IMAGING; MYOCARDITIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SARCOIDOSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEM CELL; ANIMAL; INFLAMMATION; INNERVATION; PROCEDURES; SCINTISCANNING;

ANIMALS; CELL TRACKING; HEART; HUMANS; INFLAMMATION; RADIONUCLIDE IMAGING; SYMPATHETIC NERVOUS SYSTEM; VENTRICULAR REMODELING;

EID: 84908031274     PISSN: 00012998     EISSN: 15584623     Source Type: Journal    
DOI: 10.1053/j.semnuclmed.2014.05.002     Document Type: Review

References (97)

1. M. Nahrendorf, D.E. Sosnovik, and B.A. French Multimodality cardiovascular molecular imaging, part ii Circ Cardiovasc Imaging 2 2009 56 70
2. A.J. Sinusas, F. Bengel, and M. Nahrendorf Multimodality cardiovascular molecular imaging, part i Circ Cardiovasc Imaging 1 2008 244 256
3. J.C. Wu, F.M. Bengel, and S.S. Gambhir Cardiovascular molecular imaging Radiology 244 2007 337 355
4. J.T. Thackeray, and F.M. Bengel Assessment of cardiac autonomic neuronal function using PET imaging J Nucl Cardiol 20 2013 150 165
5. I. Carrio Cardiac neurotransmission imaging J Nucl Med 42 2001 1062 1076
6. A. Flotats, I. Carrio, and D. Agostini Committee EC, European Council of Nuclear C. Proposal for standardization of 123i-metaiodobenzylguanidine (mibg) cardiac sympathetic imaging by the EANM Cardiovascular committee and the European Council of Nuclear Cardiology Eur J Nucl Med Mol Imaging 37 2010 1802 1812
7. F.M. Bengel, and M. Schwaiger Assessment of cardiac sympathetic neuronal function using PET imaging J Nucl Cardiol 11 2004 603 616
8. I. Matsunari, H. Aoki, and Y. Nomura Iodine-123 metaiodobenzylguanidine imaging and carbon-11 hydroxyephedrine positron emission tomography compared in patients with left ventricular dysfunction Circ Cardiovasc Imaging 3 2010 595 603
9. J.A. Thomas, and B.H. Marks Plasma norepinephrine in congestive heart failure Am J Cardiol 41 1978 233 243
10. J.N. Cohn, T.B. Levine, and M.T. Olivari Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure N Engl J Med 311 1984 819 823
11. D. Agostini, H.J. Verberne, and W. Burchert I-123-mibg myocardial imaging for assessment of risk for a major cardiac event in heart failure patients: Insights from a retrospective European multicenter study Eur J Nucl Med Mol Imaging 35 2008 535 546
12. P. Merlet, H. Valette, and J.L. Dubois-Rande Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure J Nucl Med 33 1992 471 477
13. A.F. Jacobson, R. Senior, and M.D. Cerqueira Investigators A-H. Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective admire-hf (adreview myocardial imaging for risk evaluation in heart failure) study J Am Coll Cardiol 55 2010 2212 2221
14. S. Malhotra, L. Wang, and C.H. Bunker Renal dysfunction does not affect the prognostic value of myocardial iodine-123 meta-iodobenzylguanidine imaging in heart failure Nucl Med Commun 35 2014 58 63
15. J.A. Fallavollita, B.M. Heavey, and A.J. Luisi Jr Regional myocardial sympathetic denervation predicts the risk of sudden cardiac arrest in ischemic cardiomyopathy J Am Coll Cardiol 63 2014 141 149
16. T. Tsukamoto, K. Morita, and M. Naya Decreased myocardial beta-adrenergic receptor density in relation to increased sympathetic tone in patients with nonischemic cardiomyopathy J Nucl Med 48 2007 1777 1782
17. M. Naya, T. Tsukamoto, and K. Morita Myocardial beta-adrenergic receptor density assessed by 11c-cgp12177 pet predicts improvement of cardiac function after carvedilol treatment in patients with idiopathic dilated cardiomyopathy J Nucl Med 50 2009 220 225
18. M.W. Dae, J.M. Herre, and J.W. O'Connell Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction J Am Coll Cardiol 17 1991 1416 1423
19. A.I. McGhie, J.R. Corbett, and M.S. Akers Regional cardiac adrenergic function using I-123 meta-iodobenzylguanidine tomographic imaging after acute myocardial infarction Am J Cardiol 67 1991 236 242
20. M.V. Simoes, P. Barthel, and I. Matsunari Presence of sympathetically denervated but viable myocardium and its electrophysiologic correlates after early revascularised, acute myocardial infarction Eur Heart J 25 2004 551 557
21. I. Matsunari, U. Schricke, and F.M. Bengel Extent of cardiac sympathetic neuronal damage is determined by the area of ischemia in patients with acute coronary syndromes Circulation 101 2000 2579 2585
22. H.P. Bulow, F. Stahl, and B. Lauer Alterations of myocardial presynaptic sympathetic innervation in patients with multi-vessel coronary artery disease but without history of myocardial infarction Nucl Med Commun 24 2003 233 239
23. T. Sasano, M.R. Abraham, and K.C. Chang Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction J Am Coll Cardiol 51 2008 2266 2275
24. M.V. Simoes, P. Barthel, and I. Matsunari Presence of sympathetically denervated but viable myocardium and its electrophysiologic correlates after early revascularised, acute myocardial infarction Eur Heart J 25 2004 551 557
25. C.M. Kramer, P.D. Nicol, and W.J. Rogers Reduced sympathetic innervation underlies adjacent noninfarcted region dysfunction during left ventricular remodeling J Am Coll Cardiol 30 1997 1079 1085
26. L. Imbert, S. Poussier, and P.R. Franken Compared performance of high-sensitivity cameras dedicated to myocardial perfusion spect: A comprehensive analysis of phantom and human images J Nucl Med 53 2012 1897 1903
27. E. Tinti, V. Positano, and A. Giorgetti Feasibility of [(123)I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: Preliminary results Eur J Nucl Med Mol Imaging 41 2014 167 173
28. C.M. Kramer, A.J. Sinusas, and D.E. Sosnovik Multimodality imaging of myocardial injury and remodeling J Nucl Med 51 suppl 1 2010 107S 121S
29. Y. Sun Intracardiac renin-angiotensin system and myocardial repair/remodeling following infarction J Mol Cell Cardiol 48 2010 483 489
30. J. Shirani, and V. Dilsizian Imaging left ventricular remodeling: Targeting the neurohumoral axis Nat Clin Pract Cardiovasc Med 5 suppl 2 2008 S57 S62
31. V. Dilsizian, W.C. Eckelman, and M.L. Loredo Evidence for tissue angiotensin-converting enzyme in explanted hearts of ischemic cardiomyopathy using targeted radiotracer technique J Nucl Med 48 2007 182 187
32. J.W. Verjans, D. Lovhaug, and N. Narula Noninvasive imaging of angiotensin receptors after myocardial infarction JACC Cardiovasc Imaging 1 2008 354 362
33. T. Higuchi, K. Fukushima, and J. Xia Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury J Nucl Med 51 2010 1956 1961
34. K. Fukushima, P.E. Bravo, and T. Higuchi Molecular hybrid positron emission tomography/computed tomography imaging of cardiac angiotensin II type 1 receptors J Am Coll Cardiol 60 2012 2527 2534
35. F.G. Spinale Matrix metalloproteinases: Regulation and dysregulation in the failing heart Circ Res 90 2002 520 530
36. E.E. Creemers, J.N. Davis, and A.M. Parkhurst Deficiency of timp-1 exacerbates lv remodeling after myocardial infarction in mice Am J Physiol Heart Circ Physiol 284 2003 H364 H371
37. H. Su, F.G. Spinale, and L.W. Dobrucki Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling Circulation 112 2005 3157 3167
38. Z.H. Sahul, R. Mukherjee, and J. Song Targeted imaging of the spatial and temporal variation of matrix metalloproteinase activity in a porcine model of postinfarct remodeling: Relationship to myocardial dysfunction Circ Cardiovasc Imaging 4 2011 381 391
39. M. Nahrendorf, K. Hu, and S. Frantz Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction Circulation 113 2006 1196 1202
40. M. Nahrendorf, E. Aikawa, and J.L. Figueiredo Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: Implications for FXIII therapy and antithrombin use in myocardial infarction Eur Heart J 29 2008 445 454
41. S.H. Lee, P.L. Wolf, and R. Escudero Early expression of angiogenesis factors in acute myocardial ischemia and infarction N Engl J Med 342 2000 626 633
42. A.M. van der Laan, J.J. Piek, and N. van Royen Targeting angiogenesis to restore the microcirculation after reperfused MI Nat Rev Cardiol 6 2009 515 523
43. G. Niu, and X. Chen Why integrin as a primary target for imaging and therapy Theranostics 1 2011 30 47
44. S. Kim, K. Bell, and S.A. Mousa Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin Am J Pathol 156 2000 1345 1362
45. L.L. Johnson, L. Schofield, and T. Donahay Radiolabeled arginine-glycine-aspartic acid peptides to image angiogenesis in swine model of hibernating myocardium JACC Cardiovasc Imaging 1 2008 500 510
46. D.F. Meoli, M.M. Sadeghi, and S. Krassilnikova Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction J Clin Invest 113 2004 1684 1691
47. T. Higuchi, F.M. Bengel, and S. Seidl Assessment of alphavbeta3 integrin expression after myocardial infarction by positron emission tomography Cardiovasc Res 78 2008 395 403
48. H.M. Sherif, A. Saraste, and S.G. Nekolla Molecular imaging of early alphavbeta3 integrin expression predicts long-term left-ventricle remodeling after myocardial infarction in rats J Nucl Med 53 2012 318 323
49. M.R. Makowski, U. Ebersberger, and S. Nekolla In vivo molecular imaging of angiogenesis, targeting alphavbeta3 integrin expression, in a patient after acute myocardial infarction Eur Heart J 29 2008 2201
50. M. Rodriguez-Porcel, W. Cai, and O. Gheysens Imaging of vegf receptor in a rat myocardial infarction model using PET J Nucl Med 49 2008 667 673
51. N.N. Danial, and S.J. Korsmeyer Cell death: Critical control points Cell 116 2004 205 219
52. S. Elmore Apoptosis: A review of programmed cell death Toxicol Pathol 35 2007 495 516
53. K. Ohtsuki, K. Akashi, and Y. Aoka Technetium-99m hynic-annexin V: A potential radiopharmaceutical for the in-vivo detection of apoptosis Eur J Nucl Med 26 1999 1251 1258
54. H. Fliss, and D. Gattinger Apoptosis in ischemic and reperfused rat myocardium Circ Res 79 1996 949 956
55. E.A. Dumont, C.P. Reutelingsperger, and J.F. Smits Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart Nat Med 7 2001 1352 1355
56. L. Hofstra, I.H. Liem, and E.A. Dumont Visualisation of cell death in vivo in patients with acute myocardial infarction Lancet 356 2000 209 212
57. J. Taki, T. Higuchi, and A. Kawashima Detection of cardiomyocyte death in a rat model of ischemia and reperfusion using 99mTc-labeled annexin V J Nucl Med 45 2004 1536 1541
58. A.F. Godier-Furnemont, Y. Tekabe, and M. Kollaros Noninvasive imaging of myocyte apoptosis following application of a stem cell-engineered delivery platform to acutely infarcted myocardium J Nucl Med 54 2013 977 983
59. B.L. Kietselaer, C.P. Reutelingsperger, and H.H. Boersma Noninvasive detection of programmed cell loss with 99mTc-labeled annexin A5 in heart failure J Nucl Med 48 2007 562 567
60. C. Peker, L. Sarda-Mantel, and P. Loiseau Imaging apoptosis with (99m)Tc-annexin-V in experimental subacute myocarditis J Nucl Med 45 2004 1081 1086
61. J. Narula, E.R. Acio, and N. Narula Annexin-V imaging for noninvasive detection of cardiac allograft rejection Nat Med 7 2001 1347 1352
62. R.J. Bennink, M.J. van den Hoff, and F.J. van Hemert Annexin V imaging of acute doxorubicin cardiotoxicity (apoptosis) in rats J Nucl Med 45 2004 842 848
63. M. Zhao, X. Zhu, and S. Ji 99mTc-labeled c2a domain of synaptotagmin I as a target-specific molecular probe for noninvasive imaging of acute myocardial infarction J Nucl Med 47 2006 1367 1374
64. A. Challapalli, L.M. Kenny, and W.A. Hallett 18F-ICMT-11, a caspase-3-specific pet tracer for apoptosis: Biodistribution and radiation dosimetry J Nucl Med 54 2013 1551 1556
65. J.H. Rudd, J. Narula, and H.W. Strauss Imaging atherosclerotic plaque inflammation by fluorodeoxyglucose with positron emission tomography: Ready for prime time? J Am Coll Cardiol 55 2010 2527 2535
66. I. Schatka, and F.M. Bengel Advanced imaging of cardiac sarcoidosis J Nucl Med 55 2014 99 106
67. J. Meller, C.O. Sahlmann, and T. Liersch Nonprosthesis orthopedic applications of (18)F fluoro-2-deoxy-D-glucose PET in the detection of osteomyelitis Radiol Clin North Am 45 2007 719 733 [vii-viii]
68. B.A. Mc Ardle, E. Leung, and H. Ohira The role of F(18)-fluorodeoxyglucose positron emission tomography in guiding diagnosis and management in patients with known or suspected cardiac sarcoidosis J Nucl Cardiol 20 2013 297 306
69. G. Youssef, E. Leung, and I. Mylonas The use of 18F-FDG PET in the diagnosis of cardiac sarcoidosis: A systematic review and metaanalysis including the ontario experience J Nucl Med 53 2012 241 248
70. E.F. Lewis, L.A. Moye, and J.L. Rouleau Predictors of late development of heart failure in stable survivors of myocardial infarction: The care study J Am Coll Cardiol 42 2003 1446 1453
71. N.G. Frangogiannis Regulation of the inflammatory response in cardiac repair Circ Res 110 2012 159 173
72. M. Nahrendorf, M.J. Pittet, and F.K. Swirski Monocytes: Protagonists of infarct inflammation and repair after myocardial infarction Circulation 121 2010 2437 2445
73. F.M. Bengel, R.T. George, and K.H. Schuleri Image-guided therapies for myocardial repair: Concepts and practical implementation Eur Heart J Cardiovasc Imaging 14 2013 741 751
74. W.W. Lee, B. Marinelli, and A.M. van der Laan PET/MRI of inflammation in myocardial infarction J Am Coll Cardiol 59 2012 153 163
75. R. Lautamäki, K.H. Schuleri, and T. Sasano Integration of infarct size, tissue perfusion, and metabolism by hybrid cardiac positron emission tomography/computed tomography: Evaluation in a porcine model of myocardial infarction Circ Cardiovasc Imaging 2 2009 299 305
76. C. Rischpler, S.G. Nekolla, and I. Dregely Hybrid PET/MR imaging of the heart: Potential, initial experiences, and future prospects J Nucl Med 54 2013 402 415
77. L.M. Riou, M. Ruiz, and G.W. Sullivan Assessment of myocardial inflammation produced by experimental coronary occlusion and reperfusion with 99mTc-rp517, a new leukotriene b4 receptor antagonist that preferentially labels neutrophils in vivo Circulation 106 2002 592 598
78. M. Nahrendorf, E. Keliher, and P. Panizzi 18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis JACC Cardiovasc Imaging 2 2009 1213 1222
79. T. Ueno, P. Dutta, and E. Keliher Nanoparticle PET-CT detects rejection and immunomodulation in cardiac allografts Circ Cardiovasc Imaging 6 2013 568 573
80. C. Wangler, R. Schirrmacher, and P. Bartenstein Click-chemistry reactions in radiopharmaceutical chemistry: Fast & easy introduction of radiolabels into biomolecules for in vivo imaging Curr Med Chem 17 2010 1092 1116
81. M. Anton, C. Wittermann, and R. Haubner Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: An in vitro evaluation J Nucl Med 45 2004 1743 1746
82. F.M. Bengel, M. Anton, and N. Avril Uptake of radiolabeled 2'-fluoro-2'-deoxy-5-iodo-1-beta-d-arabinofuranosyluracil in cardiac cells after adenoviral transfer of the herpesvirus thymidine kinase gene: The cellular basis for cardiac gene imaging Circulation 102 2000 948 950
83. M.A. Laflamme, and C.E. Murry Regenerating the heart Nat Biotechnol 23 2005 845 856
84. T. Reffelmann, S. Konemann, and R.A. Kloner Promise of blood- and bone marrow-derived stem cell transplantation for functional cardiac repair: Putting it in perspective with existing therapy J Am Coll Cardiol 53 2009 305 308
85. M. Hofmann, K.C. Wollert, and G.P. Meyer Monitoring of bone marrow cell homing into the infarcted human myocardium Circulation 111 2005 2198 2202
86. A. Aicher, W. Brenner, and M. Zuhayra Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling Circulation 107 2003 2134 2139
87. P. Musialek, L. Tekieli, and M. Kostkiewicz Randomized transcoronary delivery of CD34(+) cells with perfusion versus stop-flow method in patients with recent myocardial infarction: Early cardiac retention of 99mTc-labeled cells activity J Nucl Cardiol 18 2011 104 116
88. F.M. Bengel Noninvasive stem cell tracking J Nucl Cardiol 18 2011 966 973
89. S. Zhang, A. Sun, and D. Xu Impact of timing on efficacy and safetyof intracoronary autologous bone marrow stem cells transplantation in acute myocardial infarction: A pooled subgroup analysis of randomized controlled trials Clin Cardiol 32 2009 458 466
90. V. Schachinger, A. Aicher, and N. Dobert Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium Circulation 118 2008 1425 1432
91. J. Terrovitis, R. Lautamaki, and M. Bonios Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery J Am Coll Cardiol 54 2009 1619 1626
92. M. Krishnan, J.M. Park, and F. Cao Effects of epigenetic modulation on reporter gene expression: Implications for stem cell imaging FASEB J 20 2006 106 108
93. M. Miyagawa, M. Beyer, and B. Wagner Cardiac reporter gene imaging using the human sodium/iodide symporter gene Cardiovasc Res 65 2005 195 202
94. J. Terrovitis, K.F. Kwok, and R. Lautamaki Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography J Am Coll Cardiol 52 2008 1652 1660
95. F. Cao, S. Lin, and X. Xie In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery Circulation 113 2006 1005 1014
96. M. Gyongyosi, J. Blanco, and T. Marian Serial noninvasive in vivo positron emission tomographic tracking of percutaneously intramyocardially injected autologous porcine mesenchymal stem cells modified for transgene reporter gene expression Circ Cardiovasc Imaging 1 2008 94 103
97. N. Sun, A. Lee, and J.C. Wu Long term non-invasive imaging of embryonic stem cells using reporter genes Nat Protoc 4 2009 1192 1201