Iodine-123 metaiodobenzylguanidine imaging and carbon-11 hydroxyephedrine positron emission tomography compared in patients with left ventricular dysfunction

Circulation: Cardiovascular Imaging

Volumn 3, Issue 5, 2010, Pages 595-603

  Matsunari, Ichiro ^a   Aoki, Hirofumi ^b   Nomura, Yusuke ^b   Takeda, Nozomi ^a   Chen, Wei Ping ^a   Taki, Junichi ^c   Nakajima, Kenichi ^c   Nekolla, Stephan G ^d   Kinuya, Seigo ^c   Kajinami, Kouji ^b  

^a Medical and Pharmacological Research Center Foundation   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY HOSPITAL   (Japan)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Nervous system; Radioisotopes; Sympathetic; Tomography

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; HYDROXYEPHEDRINE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; (3 IODOBENZYL)GUANIDINE; 3 HYDROXYEPHEDRINE; 3-HYDROXYEPHEDRINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; EPHEDRINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HUMAN; IMAGE QUALITY; MALE; MEDIASTINUM; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ADRENERGIC SYSTEM; COMPARATIVE STUDY; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; INNERVATION; MIDDLE AGED; OBSERVER VARIATION; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; REPRODUCIBILITY; RETROSPECTIVE STUDY; SCINTISCANNING;

3-IODOBENZYLGUANIDINE; AGED; AGED, 80 AND OVER; EPHEDRINE; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; OBSERVER VARIATION; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; STROKE VOLUME; SYMPATHETIC NERVOUS SYSTEM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 77957332484     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.109.920538     Document Type: Article

References (35)

1. Imamura Y, Ando H, Mitsuoka W, Egashira S, Masaki H, Ashihara T, Fukuyama T. Iodine-123 metaiodobenzylguanidine images reflect intense myocardial adrenergic nervous activity in congestive heart failure independent of underlying cause. J Am Coll Cardiol. 1995;26:1594-1599.
2. Bengel FM, Barthel P, Matsunari I, Schmidt G, Schwaiger M. Kinetics of 123I-MIBG after acute myocardial infarction and reperfusion therapy. J Nucl Med. 1999;40:904-910. (Pubitemid 29269208)
3. Matsunari I, Schricke U, Bengel FM, Haase HU, Barthel P, Schmidt G, Nekolla SG, Schoemig A, Schwaiger M. Extent of cardiac sympathetic neuronal damage is determined by the area of ischemia in patients with acute coronary syndromes. Circulation. 2000;101:2579-2585. (Pubitemid 30350635)
4. Agostini D, Scanu P, Loiselet P, Babatasi G, Darlas Y, Grollier G, Potier JC, Bouvard G. Iodine-123-metaiodobenzylguanidine SPECT of regional cardiac adrenergic denervation in Brugada syndrome. J Nucl Med. 1998; 39:1129-1132. (Pubitemid 28326138)
5. Merlet P, Valette H, Dubois-Rande JL, Moyse D, Duboc D, Dove P, Bourguignon MH, Benvenuti C, Duval AM, Agostini D, Loisance D, Castaigne A, Syrota A. Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure. J Nucl Med. 1992;33: 471-477.
6. Imamura Y, Fukuyama T. Prognostic value of myocardial MIBG scintigraphy findings in patients with cardiomyopathy: Importance of background correction for quantification of MIBG activity. Ann Nucl Med. 2002;16:387-393. (Pubitemid 35407627)
7. Yamashina S, Yamazaki J. Neuronal imaging using SPECT. Eur J Nucl Med Mol Imaging. 2007;34(Suppl 1):S62-S73. (Pubitemid 46956022)
8. Agostini D, Verberne HJ, Burchert W, Knuuti J, Povinec P, Sambuceti G, Unlu M, Estorch M, Banerjee G, Jacobson AF. I-123-mIBG myocardial imaging for assessment of risk for a major cardiac event in heart failure patients: Insights from a retrospective European multicenter study. Eur J Nucl Med Mol Imaging. 2008;35:535-546.
9. Kasama S, Toyama T, Sumino H, Nakazawa M, Matsumoto N, Sato Y, Kumakura H, Takayama Y, Ichikawa S, Suzuki T, Kurabayashi M. Prognostic value of serial cardiac 123I-MIBG imaging in patients with stabilized chronic heart failure and reduced left ventricular ejection fraction. J Nucl Med. 2008;49:907-914. (Pubitemid 351793431)
10. Bax J, Kraft O, Buxton A, Fjeld J, Pařízek P, Agnostini D, Knuuti J, Flotats A, Arrighi J, Muxi A, Alibelli M, Banerjee G, Jacobson A. 123I-mIBG scintigraphy to predict inducibility of ventricular arrhythmias on cardiac electrophysiology testing: A prospective multicenter pilot study. Circ Cardiovasc Imaging. 2008;1:131-140.
11. Schwaiger M, Kalff V, Rosenspire K, Haka MS, Molina E, Hutchins GD, Deeb M, Wolfe E Jr, Wieland DM. Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography. Circulation. 1990;82:457-464. (Pubitemid 20257824)
12. Bengel FM, Ueberfuhr P, Schiepel N, Nekolla SG, Reichart B, Schwaiger M. Effect of sympathetic reinnervation on cardiac performance after heart transplantation. N Engl J Med. 2001;345:731-738.
13. Di Carli MF, Tobes MC, Mangner T, Levine AB, Muzik O, Chakroborty P, Levine TB. Effects of cardiac sympathetic innervation on coronary blood flow. N Engl J Med. 1997;336:1208-1215. (Pubitemid 27183650)
14. Munch G, Nguyen NT, Nekolla S, Ziegler S, Muzik O, Chakraborty P, Wieland DM, Schwaiger M. Evaluation of sympathetic nerve terminals with [(11)C]epinephrine and [(11)C]hydroxyephedrine and positron emission tomography. Circulation. 2000;101:516-523. (Pubitemid 30080866)
15. Lautamaki R, Tipre D, Bengel FM. Cardiac sympathetic neuronal imaging using PET. Eur J Nucl Med Mol Imaging. 2007;34 Suppl 1: S74-S85. (Pubitemid 46957471)
16. Nomura Y, Matsunari I, Takamatsu H, Murakami Y, Matsuya T, Taki J, Nakajima K, Nekolla SG, Chen WP, Kajinami K. Quantitation of cardiac sympathetic innervation in rabbits using 11C-hydroxyephedrine PET: Relation to 123I-MIBG uptake. Eur J Nucl Med Mol Imaging. 2006;33: 871-878. (Pubitemid 44127435)
17. Nekolla SG, Miethaner C, Nguyen N, Ziegler SI, Schwaiger M. Reproducibility of polar map generation and assessment of defect severity and extent assessment in myocardial perfusion imaging using positron emission tomography. Eur J Nucl Med. 1998;25:1313-1321. (Pubitemid 28446059)
18. O'Connor MK, Gibbons RJ, Juni JE, O'Keefe J Jr, Ali A. Quantitative myocardial SPECT for infarct sizing: Feasibility of a multicenter trial evaluated using a cardiac phantom. J Nucl Med. 1995;36:1130-1136.
19. Yamamoto K, Burnett JC Jr, Jougasaki M, Nishimura RA, Bailey KR, Saito Y, Nakao K, Redfield MM. Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy. Hypertension. 1996;28:988-994. (Pubitemid 26415815)
20. Kyuma M, Nakata T, Hashimoto A, Nagao K, Sasao H, Takahashi T, Tsuchihashi K, Shimamoto K. Incremental prognostic implications of brain natriuretic peptide, cardiac sympathetic nerve innervation, and noncardiac disorders in patients with heart failure. J Nucl Med. 2004;45: 155-163. (Pubitemid 47628373)
21. Wieland DM, Brown LE, Rogers WL, Worthington KC, Wu JL, Clinthorne NH, Otto CA, Swanson DP, Beierwaltes WH. Myocardial imaging with a radioiodinated norepinephrine storage analog. J Nucl Med. 1981;22:22-31. (Pubitemid 11213140)
22. Ungerer M, Hartmann F, Karoglan M, Chlistalla A, Ziegler S, Richardt G, Overbeck M, Meisner H, Schomig A, Schwaiger M. Regional in vivo and in vitro characterization of autonomic innervation in cardiomyopathic human heart. Circulation. 1998;97:174-180. (Pubitemid 28124675)
23. Cohn JN. Abnormalities of peripheral sympathetic nervous system control in congestive heart failure. Circulation. 1990;82:I59-I67.
24. Minami M, Yasuda H, Yamazaki N, Kojima S, Nishijima H, Matsumura N, Togashi H, Koike Y, Saito H. Plasma norepinephrine concentration and plasma dopamine-beta-hydroxylase activity in patients with congestive heart failure. Circulation. 1983;67:1324-1329. (Pubitemid 13105357)
25. Zipes DP. Influence of myocardial ischemia and infarction on autonomic innervation of heart. Circulation. 1990;82:1095-1105.
26. Sasano T, Abraham MR, Chang KC, Ashikaga H, Mills KJ, Holt DP, Hilton J, Nekolla SG, Dong J, Lardo AC, Halperin H, Dannals RF, Marban E, Bengel FM. Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction. J Am Coll Cardiol. 2008;51:2266-2275. (Pubitemid 351754990)
27. Tamaki S, Yamada T, Okuyama Y, Morita T, Sanada S, Tsukamoto Y, Masuda M, Okuda K, Iwasaki Y, Yasui T, Hori M, Fukunami M. Cardiac iodine-123 metaiodobenzylguanidine imaging predicts sudden cardiac death independently of left ventricular ejection fraction in patients with chronic heart failure and left ventricular systolic dysfunction: Results from a comparative study with signal-averaged electrocardiogram, heart rate variability, and QT dispersion. J Am Coll Cardiol. 2009;53:426-435.
28. Toyama T, Hoshizaki H, Yoshimura Y, Kasama S, Isobe N, Adachi H, Oshima S, Taniguchi K. Combined therapy with carvedilol and amiodarone is more effective in improving cardiac symptoms, function, and sympathetic nerve activity in patients with dilated cardiomyopathy: Comparison with carvedilol therapy alone. J Nucl Cardiol. 2008;15:57-64. (Pubitemid 351168514)
29. Matsunari I, Boning G, Ziegler SI, Nekolla SG, Stollfuss JC, Kosa I, Ficaro EP, Schwaiger M. Attenuation-corrected 99mTc-tetrofosmin single-photon emission computed tomography in the detection of viable myocardium: Comparison with positron emission tomography using 18F-fluorodeoxyglucose. J Am Coll Cardiol. 1998;32:927-935. (Pubitemid 28459580)
30. Matsunari I, Tanishima Y, Taki J, Ono K, Nishide H, Fujino S, Matoba M, Ichiyanagi K, Tonami N. Early and delayed technetium-99mtetrofosmin myocardial SPECT compared in normal volunteers. J Nucl Med. 1996;37:1622-1626. (Pubitemid 26337163)
31. Herzog BA, Buechel RR, Katz R, Brueckner M, Husmann L, Burger IA, Pazhenkottil AP, Valenta I, Gaemperli O, Treyer V, Kaufmann PA. Nuclear myocardial perfusion imaging with a cadmium-zinc-telluride detector technique: Optimized protocol for scan time reduction. J Nucl Med. 2010;51:46-51.
32. Caldwell JH, Kroll K, Li Z, Seymour K, Link JM, Krohn KA. Quantitation of presynaptic cardiac sympathetic function with carbon-11-metahydroxyephedrine. J Nucl Med. 1998;39:1327-1334.
33. Schafers M, Lerch H, Wichter T, Rhodes CG, Lammertsma AA, Borggrefe M, Hermansen F, Schober O, Breithardt G, Camici PG. Cardiac sympathetic innervation in patients with idiopathic right ventricular outflow tract tachycardia. J Am Coll Cardiol. 1998;32:181-186. (Pubitemid 28351060)
34. Wichter T, Schafers M, Rhodes CG, Borggrefe M, Lerch H, Lammertsma AA, Hermansen F, Schober O, Breithardt G, Camici PG. Abnormalities of cardiac sympathetic innervation in arrhythmogenic right ventricular cardiomyopathy : Quantitative assessment of presynaptic norepinephrine reuptake and postsynaptic beta-adrenergic receptor density with positron emission tomography. Circulation. 2000;101:1552-1558. (Pubitemid 30180892)
35. Caldwell JH, Link JM, Levy WC, Poole JE, Stratton JR. Evidence for preto postsynaptic mismatch of the cardiac sympathetic nervous system in ischemic congestive heart failure. J Nucl Med. 2008;49:234-241. (Pubitemid 351225661)