Analysis of amyotrophic lateral sclerosis as a multistep process: A population-based modelling study

The Lancet Neurology

Volumn 13, Issue 11, 2014, Pages 1108-1113

  Al Chalabi, Ammar ^a   Calvo, Andrea ^b,c,d   Chio, Adriano ^b,c,d   Colville, Shuna ^e   Ellis, Cathy M ^f   Hardiman, Orla ^g   Heverin, Mark ^g   Howard, Robin S ^h,i   Huisman, Mark H B ^j   Keren, Noa ^a   Leigh, P Nigel ^k   Mazzini, Letizia ^l   Mora, Gabriele ^m   Orrell, Richard W ^h,i   Rooney, James ^g   Scott, Kirsten M ⁿ   Scotton, William J ^a   Seelen, Meinie ^j   Shaw, Christopher E ^a   Sidle, Katie S ^h,i   Swingler, Robert ^e   Tsuda, Miho ^a   Veldink, Jan H ^j   Visser, Anne E ^j   van den Berg, Leonard H ^j   Pearce, Neil ^o,p   more..

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF TURIN   (Italy)

^c CITTÀ DELLA SALUTE E DELLA SCIENZA HOSPITAL   (Italy)

^d Neuroscience Institute of Turin   (Italy)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f KING S COLLEGE HOSPITAL   (United Kingdom)

^g TRINITY COLLEGE DUBLIN   (Ireland)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁱ NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^j UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^k UNIVERSITY OF SUSSEX   (United Kingdom)

^l UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^m IRCCS   (Italy)

ⁿ ADDENBROOKE S HOSPITAL   (United Kingdom)

^o LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^p MASSEY UNIVERSITY   (New Zealand)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CANCER EPIDEMIOLOGY; CONTROLLED STUDY; DISEASE REGISTRY; FEMALE; HUMAN; INCIDENCE; IRELAND; ITALY; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NETHERLANDS; ONSET AGE; POPULATION; UNITED KINGDOM; DISEASE COURSE; ENGLAND; FINLAND; HEALTH SURVEY; MIDDLE AGED; PROCEDURES; REGISTER; SCOTLAND; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; THEORETICAL MODEL;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; DISEASE PROGRESSION; ENGLAND; FEMALE; FINLAND; HUMANS; IRELAND; ITALY; LINEAR MODELS; MALE; MIDDLE AGED; MODELS, THEORETICAL; POPULATION SURVEILLANCE; REGISTRIES; SCOTLAND;

EID: 84908012653     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(14)70219-4     Document Type: Article

References (30)

1. Byrne S, Heverin M, Elamin M, et al. Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: a population-based case-control cohort study of familial and sporadic amyotrophic lateral sclerosis. Ann Neurol 2013, 74:699-708.
2. Al-Chalabi A, Lewis CM Modelling the effects of penetrance and family size on rates of sporadic and familial disease. Hum Hered 2011, 71:281-288.
3. Chio A, Mora G, Calvo A, Mazzini L, Bottacchi E, Mutani R Epidemiology of ALS in Italy: a 10-year prospective population-based study. Neurology 2009, 72:725-731.
4. Ravits JM, La Spada AR ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration. Neurology 2009, 73:805-811.
5. Brown RC, Lockwood AH, Sonawane BR Neurodegenerative diseases: An overview of environmental risk factors. Environ Health Perspect 2005, 113:1250-1256.
6. Hornsby C, Page KM, Tomlinson IP What can we learn from the population incidence of cancer? Armitage and Doll revisited. Lancet Oncol 2007, 8:1030-1038.
7. Armitage P, Doll R The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 1954, 8:1-12.
8. Fisher JC, Hollomon JH A hypothesis for the origin of cancer foci. Cancer 1951, 4:916-918.
9. Frank SA Dynamics of cancer: incidence, inheritance, and evolution 2007, Princeton University Press, Princeton, NJ.
10. Nordling CO A new theory on cancer-inducing mechanism. Br J Cancer 1953, 7:68-72.
11. Armitage P, Doll R The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 1954, 8:1-12.
12. Rooney J, Byrne S, Heverin M, et al. Survival analysis of Irish amyotrophic lateral sclerosis patients diagnosed from 1995-2010. PLoS One 2013, 8:e74733.
13. Huisman MH, Seelen M, de Jong SW, et al. Lifetime physical activity and the risk of amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2013, 84:976-981.
14. de Jong SW, Huisman MH, Sutedja NA, et al. Smoking, alcohol consumption, and the risk of amyotrophic lateral sclerosis: a population-based study. Am J Epidemiol 2012, 176:233-239.
15. Chancellor AM, Slattery JM, Fraser H, Swingler RJ, Holloway SM, Warlow CP The prognosis of adult-onset motor neuron disease: a prospective study based on the Scottish Motor Neuron Disease Register. J Neurol 1993, 240:339-346.
16. Abhinav K, Stanton B, Johnston C, et al. Amyotrophic lateral sclerosis in South-East England: a population-based study. The South-East England register for amyotrophic lateral sclerosis (SEALS Registry). Neuroepidemiology 2007, 29:44-48.
17. Forbes RB, Colville S, Parratt J, Swingler RJ The incidence of motor nueron disease in Scotland. J Neurol 2007, 254:866-869.
18. Marrie RA, Yu N, Blanchard J, Leung S, Elliott L The rising prevalence and changing age distribution of multiple sclerosis in Manitoba. Neurology 2010, 74:465-471.
19. Dorn HF, Cutler SJ Morbidity from cancer in the United States. Public Health Monogr 1959, 56:1-207.
20. Frank SA Age-specific acceleration of cancer. Curr Biol 2004, 2014:242-246.
21. Wang H, O'Reilly EJ, Weisskopf MG, et al. Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts. Arch Neurol 2011, 68:207-213.
22. Andersen PM, Al-Chalabi A Clinical genetics of amyotrophic lateral sclerosis: what do we really know?. Nat Rev Neurol 2011, 7:603-615.
23. Al-Chalabi A, Hardiman O The epidemiology of ALS: a conspiracy of genes, environment and time. Nat Rev Neurol 2013, 9:617-628.
24. Estrin WJ Amyotrophic lateral sclerosis in dizygotic twins. Neurology 1977, 27:692-694.
25. Frank SA Evolution in health and medicine Sackler colloquium: Somatic evolutionary genomics: mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration. Proc Natl Acad Sci USA 2010, 107:1725-1730.
26. Polymenidou M, Cleveland DW The seeds of neurodegeneration: prion-like spreading in ALS. Cell 2011, 147:498-508.
27. Plun-Favreau H, Lewis PA, Hardy J, Martins LM, Wood NW Cancer and neurodegeneration: between the devil and the deep blue sea. PLoS Genet 2010, 6:e1001257.
28. Andersen PM, Nilsson P, Keranen ML, et al. Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia. Brain 1997, 120:1723-1737.
29. Cudkowicz ME, McKenna-Yasek D, Sapp PE, et al. Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis. Ann Neurol 1997, 41:210-221.
30. Byrne S, Elamin M, Bede P, et al. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol 2012, 11:232-240.