Modelling the effects of penetrance and family size on rates of sporadic and familial disease

Human Heredity

Volumn 71, Issue 4, 2011, Pages 281-288

  Al Chalabi, Ammar ^a   Lewis, Cathryn M ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis; Familial; Genetic models; Penetrance; Population genetics; Segregation analysis; Sporadic

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CHINA; CHROMOSOME 9P; FAMILIAL DISEASE; FAMILIALITY; FAMILY SIZE; GENE LOCUS; GENETIC VARIABILITY; HUMAN; INHERITANCE; IRELAND; MATHEMATICAL MODEL; MUTATION RATE; PENETRANCE; SPORADIC DISEASE;

AMYOTROPHIC LATERAL SCLEROSIS; FAMILY CHARACTERISTICS; GENETIC DISEASES, INBORN; HUMANS; MODELS, GENETIC; MUTATION; PENETRANCE; PROBABILITY; SUPEROXIDE DISMUTASE;

EID: 80051586618     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000330167     Document Type: Article

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