Retinoids and glomerular regeneration

Seminars in Nephrology

Volumn 34, Issue 4, 2014, Pages 429-436

  Lazzeri, Elena ^a   Peired, Anna Julie ^a,b   Lasagni, Laura ^a   Romagnani, Paola ^a,b,c  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Glomerular regeneration; Kidney; Retinoic acid

Indexed keywords

RETINOID; RETINOIC ACID;

CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL REGENERATION; CELL RENEWAL; DISEASE ASSOCIATION; EMBRYO DEVELOPMENT; GLOMERULOSCLEROSIS; GLOMERULUS; HUMAN; KIDNEY FUNCTION; NONHUMAN; PODOCYTE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEINURIA; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL EXPANSION; CYTOLOGY; PHYSIOLOGY; REGENERATION;

CELL DIFFERENTIATION; HUMANS; KIDNEY GLOMERULUS; PODOCYTES; REGENERATION; STEM CELLS; TRETINOIN;

EID: 84907980853     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2014.06.009     Document Type: Review

References (41)

1. Remuzzi G., Benigni A., Remuzzi A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. J Clin Invest 2006, 116:288-296.
2. Remuzzi A., Gagliardini E., Sangalli F., Bonomelli M., Piccinelli M., Benigni A., et al. ACE inhibition reduces glomerulosclerosis and regenerates glomerular tissue in a model of progressive renal disease. Kidney Int 2006, 69:1124-1130.
3. Wharram B.L., Goyal M., Wiggins J.E., Sanden S.K., Hussain S., Filipiak W.E., et al. Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 2005, 16:2941-2952.
4. Macconi D., Sangalli F., Bonomelli M., Conti S., Condorelli L., Gagliardini E., et al. Podocyte repopulation contributes to regression of glomerular injury induced by ACE inhibition. Am J Pathol 2009, 174:797-807.
5. Perico N., Benigni A., Remuzzi G. Present and future drug treatments for chronic kidney diseases: evolving targets in renoprotection. Nat Rev Drug Discov 2008, 7:936-953.
6. Niederreither K., Dollé P. Retinoic acid in development: towards an integrated view. Nat Rev Genet 2008, 9:541-553.
7. White J.C., Highland M., Kaiser M., Clagett-Dame M. Vitamin A deficiency results in the dose-dependent acquisition of anterior character and shortening of the caudal hindbrain of the rat embryo. Dev Biol 2000, 220:263-284.
8. Cammas L., Romand R., Fraulob V., Mura C., Dollé P. Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev Dyn 2007, 236. 2899-08.
9. Dollé P. Developmental expression of retinoic acid receptors (RARs). Nucl Recept Signal 2009, 12:e006.
10. Mark M., Ghyselinck N.B., Chambon P. Function of retinoic acid receptors during embryonic development. Nucl Recept Signal 2009, 7:e002.
11. Gudas L.J. Retinoids induce stem cell differentiation vie epigenetic changes. Semin Cell Dev Biol 2013, 24:701-705.
12. Haskell G.T., LaMantia A.S. Retinoic acid signaling identifies a distinct precursor population in the developing and adult forebrain. J Neurosci 2005, 25:7636-7647.
13. Rhinn M., Dollé P. Retinoic acid signalling during development. Development 2012, 139:843-858.
14. Yu S., Levi L., Siegel R., Noy N. Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor β/δ (PPARβ/δ). J Biol Chem 2012, 287. 42195-05.
15. Lin S.C., Dollé P., Ryckebüsch L., Noseda M., Zaffran S., Schneider M.D., et al. Endogenous retinoic acid regulates cardiac progenitor differentiation. Proc Natl Acad Sci U S A 2010, 107:9234-9239.
16. Ghiaur G., Yegnasubramanian S., Perkins B., Gucwa J.L., Gerber J.M., Jones R.J. Regulation of human hematopoietic stem cell self-renewal by the microenvironment[U+05F3]s control of retinoic acid signaling. Proc Natl Acad Sci U S A 2013, 110:16121-16126.
17. Wingert R.A., Davidson A.J. Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b. Dev Dyn 2011, 240:2011-2027.
18. Li Y., Cheng C.N., Verdun V.A., Wingert R.A. Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling. Dev Biol 2014, 386:111-122.
19. Bollig F., Perner B., Besenbeck B., Köthe S., Ebert C., Taudien S., et al. A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros. Development 2009, 136:2883-2892.
20. Wingert R.A., Selleck R., Yu J., Song H.D., Chen Z., Song A., et al. The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. PLoS Genet 2007, 3:1922-1938.
21. Lelièvre-Pégorier M., Vilar J., Ferrier M.L., Moreau E., Freund N., Gilbert T., et al. Mild vitamin A deficiency leads to inborn nephron deficit in the rat. Kidney Int 1998, 54:1455-1462.
22. Xu Q., Lucio-Cazana J., Kitamura M., Ruan X., Fine L.G., Norman J.T. Retinoids in nephrology: promises and pitfalls. Kidney Int 2004, 66:2119-2131.
23. Wagner J., Dechow C., Morath C., Lehrke I., Amann K., Waldherr R., et al. Retinoic acid reduces glomerular injury in a rat model of glomerular damage. J Am Soc Nephrol 2000, 11:1479-1487.
24. Dechow C., Morath C., Peters J., Lehrke I., Waldherr R., Haxsen V., et al. Effects of all-trans retinoic acid on renin-angiotensin system in rats with experimental nephritis. Am J Physiol Renal Physiol 2001, 281:F909-F919.
25. Oseto S., Moriyama T., Kawada N., Nagatoya K., Takeji M., Ando A., et al. Therapeutic effect of all-trans retinoic acid on rats with anti-GBM antibody glomerulonephritis. Kidney Int 2003, 64:1241-1252.
26. Kinoshita K., Yoo B.S., Nozaki Y., Sugiyama M., Ikoma S., Ohno M., et al. Retinoic acid reduces autoimmune renal injury and increases survival in NZB/W F1 mice. J Immunol 2003, 170:5793-5798.
27. Han S.Y., So G.A., Jee Y.H., Han K.H., Kang Y.S., Kim H.K., et al. Effect of retinoic acid in experimental diabetic nephropathy. Immunol Cell Biol 2004, 82:568-576.
28. Suzuki A., Ito T., Imai E., Yamato M., Iwatani H., Kawachi H., et al. Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats. J Am Soc Nephrol 2003, 14:981-991.
29. Vaughan M.R., Pippin J.W., Griffin S.V., Krofft R., Fleet M., Haseley L., et al. ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo. Kidney Int 2005, 68:133-144.
30. He J.C., Lu T.C., Fleet M., Sunamoto M., Husain M., Fang W., et al. Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. J Am Soc Nephrol 2007, 18:93-102.
31. Zhong Y., Wu Y., Liu R., Li Z., Chen Y., Evans T., et al. Novel retinoic acid receptor alpha agonists for treatment of kidney disease. PLoS One 2011, 6:e27945.
32. Zhong Y., Wu Y., Liu R., Deng Y., Mallipattu S.K., Klotman P.E., et al. Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure. Kidney Int 2012, 81:856-864.
33. Ratnam K.K., Feng X., Chuang P.Y., Verma V., Lu T.C., Wang J., et al. Role of the retinoic acid receptor-α in HIV-associated nephropathy. Kidney Int 2011, 79:624-634.
34. Ronconi E., Sagrinati C., Angelotti M.L., Lazzeri E., Mazzinghi B., Ballerini L., et al. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol 2009, 20:322-332.
35. Romagnani P., Lasagni L., Remuzzi G. Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol 2013, 9:137-146.
36. Zhang J., Pippin J.W., Vaughan M.R., Krofft R.D., Taniguchi Y., Romagnani P., et al. Retinoids augment the expression of podocyte proteins by glomerular parietal epithelial cells in experimental glomerular disease. Nephron Exp Nephrol 2012, 121:e23-e37.
37. Peired A., Angelotti M.L., Ronconi E., la Marca G., Mazzinghi B., Sisti A., et al. Proteinuria impairs podocyte regeneration by sequestering retinoic acid. J Am Soc Nephrol 2013, 24:1756-1768.
38. Smeets B., Angelotti M.L., Rizzo P., Dijkman H., Lazzeri E., Mooren F., et al. Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. J Am Soc Nephrol 2009, 20. 2593-03.
39. Lasagni L., Romagnani P. Glomerular epithelial stem cells: the good, the bad, and the ugly. J Am Soc Nephrol 2010, 21:1612-1619.
40. Rizzo P., Perico N., Gagliardini E., Novelli R., Alison M.R., Remuzzi G., et al. Nature and mediators of parietal epithelial cell activation in glomerulonephritides of human and rat. Am J Pathol 2013, 183:1769-1778.
41. Benigni A., Morigi M., Rizzo P., Gagliardini E., Rota C., Abbate M., et al. Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture. Am J Pathol 2011, 179:628-638.