HCN4 mutations in multiple families with bradycardia and left ventricular noncompaction cardiomyopathy

Journal of the American College of Cardiology

Volumn 64, Issue 8, 2014, Pages 745-756

  Milano, Annalisa ^a   Vermeer, Alexa M C ^a   Lodder, Elisabeth M ^a   Barc, Julien ^a,b   Verkerk, Arie O ^a   Postma, Alex V ^a   Van Der Bilt, Ivo A C ^a   Baars, Marieke J H ^a   Van Haelst, Paul L ^c   Caliskan, Kadir ^d   Hoedemaekers, Yvonne M ^e   Le Scouarnec, Solena ^f,g,h   Redon, Richard ^f,g,h,i   Pinto, Yigal M ^a   Christiaans, Imke ^a   Wilde, Arthur A ^a   Bezzina, Connie R ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^c ST ANTONIUS HOSPITAL   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f L INSTITUT DU THORAX   (France)

^g CNRS   (France)

^h UNIVERSITÉ DE NANTES   (France)

ⁱ NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

exome sequencing; genetics; HCN4; ion channel; left ventricular noncompaction cardiomyopathy; sinus bradycardia

Indexed keywords

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; ATRIOVENTRICULAR BLOCK; CARDIOVERSION; CLINICAL ARTICLE; DOPPLER ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; EXOME; FAMILY HISTORY; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENE SEGREGATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; HAPLOTYPE; HEART ATRIUM FIBRILLATION; HUMAN; LINKAGE ANALYSIS; MALE; MIDDLE AGED; MITRAL VALVE PROLAPSE; MITRAL VALVE REPAIR; MUTATIONAL ANALYSIS; PEDIGREE ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SINUS BRADYCARDIA; VENTRICULAR NONCOMPACTION; YOUNG ADULT;

EXOME SEQUENCING; GENETICS; HCN4; ION CHANNEL; LEFT VENTRICULAR NONCOMPACTION CARDIOMYOPATHY; SINUS BRADYCARDIA;

ADOLESCENT; ADULT; AGED; ANIMALS; CHO CELLS; CRICETULUS; DNA MUTATIONAL ANALYSIS; EXOME; FEMALE; GENETIC LINKAGE; HEART DEFECTS, CONGENITAL; HUMANS; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; MALE; MEMBRANE POTENTIALS; MIDDLE AGED; MUSCLE PROTEINS; POTASSIUM CHANNELS; SICK SINUS SYNDROME; SYNDROME; YOUNG ADULT;

EID: 84907951338     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.05.045     Document Type: Article

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