Abdominal obesity and low physical activity are associated with insulin resistance in overweight adolescents: A cross-sectional study

BMC Pediatrics

Volumn 14, Issue 1, 2014, Pages 1-9

  Velásquez Rodríguez, Claudia María ^a   Velásquez Villa, Marcela ^a   Gómez Ocampo, Leidy ^a   Bermúdez Cardona, Juliana ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Abdominal obesity; Adolescents; Insulin resistance; Metabolic syndrome; Physical activity

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; LIPID;

ABDOMINAL OBESITY; ADOLESCENT; ADOLESCENT DISEASE; ADULT; ANTHROPOMETRY; ARTICLE; BODY MASS; CARBOHYDRATE INTAKE; CARDIOVASCULAR RISK; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; EDUCATIONAL STATUS; FAT INTAKE; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HUMAN; INFLAMMATION; INSULIN RESISTANCE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLIC EQUIVALENT; PHYSICAL ACTIVITY; PROTEIN INTAKE; PUBERTY; RISK FACTOR; SEDENTARY LIFESTYLE; SOCIAL STATUS; TELEVISION VIEWING; WAIST CIRCUMFERENCE; WEIGHT CONTROL; BLOOD; CASE CONTROL STUDY; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; STATISTICAL MODEL;

ADOLESCENT; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INSULIN RESISTANCE; LINEAR MODELS; LIPIDS; MALE; OBESITY, ABDOMINAL; OVERWEIGHT; SEDENTARY LIFESTYLE;

EID: 84907948539     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-14-258     Document Type: Article

References (75)

1. De Boer MD. Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions. Nutrition 2013, 29:379-386. 10.1016/j.nut.2012.07.003, 3578702, 23022122.
2. Friend A, Craig L, Turner S. The prevalence of metabolic syndrome in children: a systematic review of the literature. Metab Syndr Relat Disord 2013, 11:71-80. 10.1089/met.2012.0122, 23249214.
3. Stupar D, Eide WB, Bourne L, Hendricks M, Iversen PO, Wandel M. The nutrition transition and the human right to adequate food for adolescents in the Cape Town metropolitan area: implications for nutrition policy. Food Policy 2012, 37:199-206.
4. Popkin BM, Adair LS, Ng SW. Global nutrition transition and the pandemic of obesity in developing countries. Nutr Rev 2012, 70:3-21. 10.1111/j.1753-4887.2011.00456.x, 3257829, 22221213.
5. Instituto Colombiano de Bienestar Familiar, Profamilia, Instituto Nacional De Salud, Escuela de Nutrición y Dietética Universidad de Antioquia, Organización Panamericana de la Salud Encuesta nacional de la situación nutricional en Colombia 2006, Bogotá: Panamericana Formas e Impresos, S.A, Instituto Colombiano de Bienestar Familiar, Profamilia, Instituto Nacional De Salud, Escuela de Nutrición y Dietética Universidad de Antioquia, Organización Panamericana de la Salud.
6. Profamilia, Instituto Nacional De Salud, Bienestar Familiar, Ministerio de la Proteccion Social, Prosperidad para todos Encuesta Nacional de la Situación Nutricional en Colombia 2011, Bogotá: Da Vinci Editores & Cia. SNC, Profamilia, Instituto Nacional De Salud, Bienestar Familiar, Ministerio de la Proteccion Social, Prosperidad para todos.
7. Alvarez LS, Mancilla LP, González LI, Isaza UA. Perfil Alimentario y Nutricional de Medellín 2010, Medellín: Secretaría de Bienestar Social.
8. Hajer GR, van Haeften TW, Visseren FLJ. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J 2008, 29:2959-2971. 10.1093/eurheartj/ehn387, 18775919.
9. Valerio G, Licenziati MR, Iannuzzi A, Franzese A, Siani P, Riccardi G. Insulin resistance and impaired glucose tolerance in obese children and adolescents from Southern Italy. Nutr Metab Cardiovasc Dis 2006, 16:279-284. 10.1016/j.numecd.2005.12.007, 16679220.
10. Ochoa Agudelo GM, Arias Arteaga R. Prevalence of the metabolic syndrome in school children and adolescents of the urban area of Medellín, Colombia. Iatreia 2008, 21:260-270.
11. Agudelo G, Velásquez C, Bedoya G, Estrada A, Manjarrés L, Patiño F. Variations in the prevalence of metabolic syndrome in adolescents according to different criteria used for diagnosis: Which definition should be chosen for this age group?. Metab Syndr Relat Disord 2014, 12:202-209. 10.1089/met.2013.0127, 24564686.
12. Prentki M, Nolan CJ. Islet β cell failure in type 2 diabetes. J Clin Invest 2006, 116:1802-1812. 10.1172/JCI29103, 1483155, 16823478.
13. Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW. Obesity and metabolic syndrome in children and adolescents. N Engl J Med 2004, 350:2362-2374. 10.1056/NEJMoa031049, 15175438.
14. Celik T, Iyisoy A, Yuksel UC. Pediatric metabolic syndrome: a growing threat. Int J Cardiol 2010, 142:302-303. 10.1016/j.ijcard.2008.11.143, 19097654.
15. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents. Arch Pediatr 2003, 157:821-827.
16. Kassi E, Pervanidou P, Kaltsas G, Chrousos G. Metabolic syndrome: definitions and controversies. BMC Med 2011, 9:48. 10.1186/1741-7015-9-48, 3115896, 21542944.
17. Olivares Reyes JA, Arellano Plancarte A. Bases Moleculares de las Acciones de la Insulina. Revista Educ Bioquím 2008, 27:9-18.
18. Garmendia ML, Lera L, Sánchez H, Uauy R, Albala C. Homeostasis model assessment (HOMA) values in Chilean elderly subjects. Med Chile 2009, 137:1409-1416.
19. Acosta García E, Carías D, Páez Valery M, Naddaf G, Zury D. Exceso de peso, resistencia a la insulina y dislipidemia en adolescentes. Acta Bioquím Clín Latinoam 2012, 46:365-373.
20. Koike T, Miyamoto M, Oshida Y. Waist circumference is positively associated with insulin resistance but not with fasting blood glucose among moderately to highly obese young Japanese men. Obes Res Clin Pract 2009, 3:109-114.
21. Simarro Rueda M, Carbayo Herencia JA, Massó Orozco J, Artigao Rodenas LM, Carrión Valero L, Divisón Garrote JA. Association of insulin resistance with different anthropometric measures and cardiovascular risk factors in a non-diabetic population. Endocrinol Nutr 2011, 58:464-471. 10.1016/j.endonu.2011.06.003, 21963533.
22. Kotlyarevska K, Wolfgram P, Lee J. Is waist circumference a better predictor of insulin resistance than body mass index in U.S. adolescents?. J Adolesc Health 2011, 49:330-333. 10.1016/j.jadohealth.2010.12.008, 3188962, 21856529.
23. Abete I, Goyenechea E, Zulet MA, Martínez JA. Obesity and metabolic syndrome: potential benefit from specific nutritional components. Nutr Metab Cardiovasc Dis 2011, 21:B1-B15.
24. Yeste D, Carrascosa A. Obesity-related metabolic disorders in childhood and adolescence. Ann Pediatr (Paris) 2011, 75:135. e1- 9.
25. Androutsos O, Moschonis G, Mavrogianni C, Roma-Giannikou E, Chrousos GP, Kanaka-Gantenbein C. Identification of lifestyle patterns, including sleep deprivation, associated with insulin resistance in children: the healthy growth study. Eur J Clin Nutr 2014, 68:344-349. 10.1038/ejcn.2013.280, 24424081.
26. National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, evaluation, and treatment of high blood cholesterol in adults, (adult treatment panel III). Final report. Circulation 2002, 106:3143-3421. National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on.
27. Sesé MA, Jiménez-Pavón D, Gilbert CC, González-Gross M, Gottrand F, de Henauw S. Eating behaviour, insulin resistance and cluster of metabolic risk factors in European adolescents: the HELENA study. Appetite 2012, 59:140-147. 10.1016/j.appet.2012.04.011, 22524997.
28. Mirza N, Palmer M, O'Connell J, Dipietro L. Independent benefits of meeting the 2008 physical activity guidelines to insulin resistance in obese Latino children. J Obes 2012, 2012:1-7.
29. Levy-Marchal C, Arslanian S, Cutfield W, Sinaiko A, Druet C, Marcovecchio ML. Insulin resistance in children: consensus, perspective, and future directions. J Clin Endocrinol Metab 2010, 95:5189-5198. 10.1210/jc.2010-1047, 3206517, 20829185.
30. Chu SH, Park J-H, Lee MK, Jekal Y, Ahn KY, Chung JY. The association between pentraxin 3 and insulin resistance in obese children at baseline and after physical activity intervention. Clin Chim Acta 2012, 413:1430-1437. 10.1016/j.cca.2012.06.002, 22687644.
31. Patiño Villada FA, Márquez Arabia JJ, Uscátegui Peñuela RM, Estrada Restrepo A, Agudelo Ochoa GM, Manjarrés LM. Effect of an intervention with physical exercise and nutritional guidance on the components of the metabolic syndrome among young people with overweight. Iatreia 2013, 26:34-43.
32. Rodríguez-Rodríguez E, Perea JM, López-Sobaler AM, Ortega RM. Obesity, insulin resistance and increase in adipokines levels: importance of the diet and physical activity. Nutr Hosp 2009, 24:415-421.
33. Bolet Astoviza M, Socorrás Suárez MM. An appropriate feeding to impove the health and to avoid chronic diseases. Rev Cuba Med Gen Integr 2010, 26:321-329.
34. Ambrosini GL, Huang RC, Mori TA, Hands BP, O'Sullivan TA, de Klerk NH. Dietary patterns and markers for the metabolic syndrome in Australian adolescents. Nutr Metab Cardiovasc Dis 2010, 20:274-283. 10.1016/j.numecd.2009.03.024, 19748245.
35. Nasreddine L, Naja F, Tabet M, Habbal M-Z, El-Aily A, Haikal C. Obesity is associated with insulin resistance and components of the metabolic syndrome in Lebanese adolescents. Ann Hum Biol 2012, 39:122-128. 10.3109/03014460.2012.655776, 3310480, 22324838.
36. Uscátegui Peñuela RM, Álvarez Uribe MC, Laguado Salinas I, Soler Terranova W, Martínez Maluendas L, Arias Arteaga R. Cardiovascular risk factors in children and teenagers aged 6-18 years olf from medillín (Colombia). Ann Pediatr (Paris) 2003, 58:411-417.
37. DANE Modelo de Reglamento del Comité Permanente de Estratificación Socioeconómica. [http://www.dane.gov.co/index.php?option=com_content&view=article&id=366&Itemid=114], DANE.
38. Fernández JR, Redden DT, Pietrobelli A, Allison DB. Waist circumference percentiles in nationally representative samples of African-American, European American, and Mexican-American children and adolescents. J Pediatr 2004, 145:439-444. 10.1016/j.jpeds.2004.06.044, 15480363.
39. Lohman TG, Roche AF, Martorell F. Anthropometric standardization reference manual 1988, Champaign, IL: Human Kinetics Books.
40. De Onis M, Onyango AW, Borghi E, Siyam A, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 2007, 85:660-667. 10.2471/BLT.07.043497, 2636412, 18026621.
41. Colombia. Ministerio de la Protección Social Resolución 2121 de 2010, Junio 9, por la cual se adoptan los Patrones de crecimiento publicados por la Organización Mundial de la Salud, OMS, en el 2006 y 2007 para los niños, niñas y adolescentes de 0 a 18 años de edad y se dictan otras disposiciones 2010, Bogotá: El Ministerio, Colombia. Ministerio de la Protección Social.
42. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004, 114(Suppl 2):555-576. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents.
43. Marshall WA, Tanner JM. Variations in pattern of pubertal changes in girls. Arch Dis Child 1969, 44:291-303. 10.1136/adc.44.235.291, 2020314, 5785179.
44. Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child 1970, 45:13-23. 10.1136/adc.45.239.13, 2020414, 5440182.
45. Daniels SR, Benuck I, Christakis DA, Dennison BA, Gidding SS, Gillman MW. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics 2012, 128(Suppl 5):213-259.
46. Argüeso AR, Díaz Díaz J, Díaz Peromingo J, Rodríguez González A, Castro Mao M, Diz Lois F. Lípidos, colesterol y lipoproteínas. Galicia Clin 2011, 72:7-17.
47. Lee JM, Okumura MJ, Davis MM, Herman WH, Gurney JG. Prevalence and determinants of insulin resistance among U.S. adolescents: a population-based study. Diabetes Care 2006, 29:2427-2432. 10.2337/dc06-0709, 17065679.
48. Yin J, Li M, Xu L, Wang Y, Cheng H, Zhao X. Insulin resistance determined by Homeostasis Model Assessment (HOMA) and associations with metabolic syndrome among Chinese children and teenagers. Diab Metab Syndr 2013, 5:71.
49. Myers GL, Rifai N, Tracy RP, Roberts WL, Alexander RW, Biasucci LM. CDC/AHA workshop on markers of inflammation and cardiovascular disease: application to clinical and public health practice: report from the laboratory science discussion group. Circulation 2004, 110:545-549.
50. Food and Nutrition Board Institute of Medicine Dietary Reference Intakes. Application in Dietary Assessment 2000, Washington DC: National Academy Press, Food and Nutrition Board Institute of Medicine.
51. Manjarrés LM. Reliable data collected method about food intake in population studies. Perspect Nutr Hum 2008, 9:155-163.
52. Manjarrés LM, Manjarrés S. Programa de Evaluación de Ingesta Dietética EVINDI v4. [Software] 2008, Medellín: Universidad de Antioquia-Escuela de Nutrición y Dietética.
53. Colombian Family Welfare Institute Colombian Food Composition Table 2007, Bogota: ICBF, Colombian Family Welfare Institute.
54. FAO/LATINFOODS Tabla de Composición de Alimentos de América Latina. [http://www.rlc.fao.org/es/conozca-fao/que-hace-fao/estadisticas/composicion-alimentos/busqueda/], FAO/LATINFOODS.
55. USDA Composition of Foods Raw, Processed, Prepared. [http://ndb.nal.usda.gov/ndb], USDA.
56. Pate RR, Ross R, Trost SG, Sirard JR, Dowda M. Validation of a 3-day physical activity recall instrument in female youth. Pediatr Exerc Sci 2003, 15:257-265.
57. Dowda M, Saunders RP, Hastings L, Gay JM, Evans AE. Physical activity and sedentary pursuits of children living in residential children's homes. J Phys Act Health 2009, 6:195-202.
58. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 2000, 32:498-516.
59. Lafontan M. Adipose tissue and adipocyte dysregulation. Diabetes Metab 2013, 40:16-28.
60. Saito E, Okada T, Abe Y, Odaka M, Kuromori Y, Iwata F. Abdominal adiposity is associated with fatty acid desaturase activity in boys: implications for C-reactive protein and insulin resistance. Prostaglandins Leukot Essent Fatty Acids 2013, 88:307-311. 10.1016/j.plefa.2013.01.005, 23419767.
61. Giannini C, de Giorgis T, Scarinci A, Ciampani M, Marcovecchio ML, Chiarelli F. Obese related effects of inflammatory markers and insulin resistance on increased carotid intima media thickness in pre-pubertal children. Atherosclerosis 2008, 197:448-456. 10.1016/j.atherosclerosis.2007.06.023, 17681348.
62. Bremer A, Mietus-Snyder M, Lustig R. Toward a unifying hypothesis of metabolic syndrome. Pediatrics 2012, 129:557-570. 10.1542/peds.2011-2912, 3289531, 22351884.
63. Meshkani R, Adeli K. Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clin Biochem 2009, 42:1331-1346. 10.1016/j.clinbiochem.2009.05.018, 19501581.
64. Maffeis C, Banzato C, Brambilla P, Cerutti F, Corciulo N, Cuccarolo G. Insulin resistance is a risk factor for high blood pressure regardless of body size and fat distribution in obese children. Nutr Metab Cardiovasc Dis 2010, 20:266-273. 10.1016/j.numecd.2009.04.005, 19748246.
65. Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 2011, 378:169-181. 10.1016/S0140-6736(11)60614-4, 21705072.
66. Fedewa MV, Gist NH, Evans EM, Dishman RK. Exercise and insulin resistance in youth: a meta-analysis. Pediatrics 2014, 133:163-174.
67. Moran A, Jacobs DR, Steinberger J, Hong CP, Prineas R, Luepker R. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999, 48:2039-2044. 10.2337/diabetes.48.10.2039, 10512371.
68. Rizzo NS, Ruiz JR, Oja L, Veidebaum T, Sjöström M. Associations between physical activity, body fat, and insulin resistance (homeostasis model assessment) in adolescents: the European Youth Heart Study. Am J Clin Nutr 2008, 87:586-592.
69. Rosenbloom AL, Silverstein JH, Amemiya S, Zeitler P, Klingensmith GJ. Type 2 diabetes in children and adolescents. Pediatr Diabetes 2009, 10:17-32.
70. American College of Sports Medicine Exercise and type 2 diabetes. Off J Am Coll Sport Med 2000, 32:1345-1360. American College of Sports Medicine.
71. Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care 2010, 33:2692-2696. 10.2337/dc10-1548, 2992214, 21115771.
72. Zanuso S, Jimenez A, Pugliese G, Corigliano G, Balducci S. Exercise for the management of type 2 diabetes: a review of the evidence. Acta Diabetol 2010, 47:15-22. 10.1007/s00592-009-0126-3, 19495557.
73. Suh S, Jeong I-K, Kim MY, Kim YS, Shin S, Kim SS. Effects of resistance training and aerobic exercise on insulin sensitivity in overweight korean adolescents: a controlled randomized trial. Diabetes Metab J 2011, 35:418-426. 10.4093/dmj.2011.35.4.418, 3178704, 21977463.
74. Anderson CB, Hagströmer M, Yngve A. Validation of the PDPAR as an adolescent diary: effect of accelerometer cut points. Med Sci Sports Exerc 2005, 7:1224-1230.
75. Gutin B, Owens S. The influence of physical activity on cardiometabolic biomarkers in youths: a review. Pediatr Exerc Sci 2011, 23:169-185.