Homeostasis model assessment (HOMA) values in chilean elderly subjects;Valores normativos de resistencia a la insulina mediante HOMA-IR en adultos mayores de Santiago de Chile

Revista Medica de Chile

Volumn 137, Issue 11, 2009, Pages 1409-1416

  Garmendia, María Luisa ^a   Lera, Lydia ^b   Sánchez, Hugo ^b   Uauy, Ricardo ^b   Albala, Cecilia ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Aged; Diabetes mellitus; Hyperinsulinism; Insulin resistance

Indexed keywords

BASAL INSULIN; DRUG DERIVATIVE; INSULIN; GLUCOSE BLOOD LEVEL; LONG ACTING INSULIN;

AGED; ARTICLE; BIOLOGICAL MODEL; BLOOD; BODY MASS; CHILE; EPIDEMIOLOGY; FEMALE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; MALE; MIDDLE AGED; PHYSIOLOGY; REFERENCE VALUE; ANALOGS AND DERIVATIVES; ANALYSIS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; BODY MASS INDEX; CHILE; EPIDEMIOLOGIC METHODS; FEMALE; HOMEOSTASIS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; REFERENCE VALUES; INSULIN, LONG-ACTING;

EID: 72249106736     PISSN: 00349887     EISSN: 07176163     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Meigs Jb, Rutter Mk, Sullivan Lm, Fox Cs, D'Agostino Rb, Sr, Wilson Pw. Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome. Diabetes Care 2007; 30: 1219-25.
2. Grundy SM. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. Am J Cardiol 1999; 83: 25F-9F.
3. Iozzo P, Beck-Nielsen H, Laakso M, smith U, Yki-Jarvinen H, Ferrannini E. Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance. J Clin Endocrinol Metab 1999; 84: 863-8.
4. Defronzo R, Tobin J, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: 214-23.
5. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-9.
6. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, zenere MB et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies insubjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 2000; 23: 57-63.
7. Emoto M, Nishizawa Y, Maekawa K, Hiura Y, Kanda h, Kawagishi T et al. Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 1999; 22: 818-22.
8. Katsuki A, Sumida Y, Gabazza EC, Murashima S, Furuta M, Araki-Sasaki R Et Al. Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes. Diabetes Care 2001; 24: 362-5.
9. Chang AM, Smith MJ, Bloem CJ, Galecki AT, Halter JB, Supiano MA. Limitation of the homeostasis model assessment to predict insulin resistance and beta-cell dysfunction in older people. J Clin Endocrinol Metab 2006; 91: 629-34.
10. Vasques AC, Rosado LE, de Cassia GR, Geloneze B. [Critical analysis on the use of the homeostasis model assessment (HOMA) indexes in the evaluation of the insulin resistance and the pancreatic beta cells functional capacity]. Arq Bras Endocrinol Metabol 2008; 52: 32-9.
11. Rutter MK, Wilson PW, Sullivan LM, Fox CS, D'Agostino RB, SR, Meigs JB. Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease. Circulation 2008; 117: 1003-9.
12. Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Targher G Et Al. Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. Diabetes 1998; 47: 1643-9.
13. Matsumoto K, Miyake S, Yano M, Ueki Y, Yamaguchi Y, Akazawa S Et Al. Glucose tolerance, insulin secretion, and insulin sensitivity in nonobese and obese Japanese subjects. Diabetes Care 1997; 20: 1562-8.
14. Acosta A, Escalona M, Maiz A, Pollak F, Leighton F. Determinación del índice de resistencia insulínica mediante HOMA en una población de la Región Metropolitana de Chile. Rev Méd Chile 2002; 130: 1227-31.
15. Dangour AD, Albala C, Aedo C, Elbourne D, grundy E, walker D et al. A factorial-design cluster randomized controlled trial investigating the cost-effectiveness of a nutrition supplement and an exercise programme on pneumonia incidence, walking capacity and body mass index in older people living in Santiago, Chile: the CENEX study protocol. Nutrition Journal 2007; 6: 14.
16. Albala C, Kebrão ML, León Díaz EM, Ham-Chande R, Hennis A, Palloni A et al. Encuesta Salud, Bienestar y Envejecimiento (SABE): metodología de la encuesta y perfil de la población estudiada. Revista Panamericana de Salud Pública 2005; 17: 307-22.
17. Ascaso JF, Romero P, Real JT, Lorente RJ, Martínez-Valls J, Carmena R. Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population. Eur J Intern Med 2003; 14: 101-6.
18. WORLD HEALTH ORGANIZATION. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation. Geneva: World Health Organization; 2000.
19. Grundy SM, Cleeman JJ, Caniels SR, Donato KA, Eckel RH, Franklin BA et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-52.
20. Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Meigs JB Et Al. Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study. Diabetes Care 2007; 30: 318-24.
21. Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004; 27: 1487-95.
22. Ferrara CM, Goldberg AP. Limited value of the homeostasis model assessment to predict insulin resistance in older men with impaired glucose tolerance. Diabetes Care 2001; 24: 245-9.
23. Lichnovska R, Gwozdziewiczova S, Hrebicek J. Gender differences in factors influencing insulin resistance in elderly hyperlipemic non-diabetic subjects. Cardiovasc Diabetol 2002; 1: 4.
24. Motta M, Bennati E, Ferlito L, Passamonte M, Malaguarnera M. Insulin-resistance (IR) in older age. Arch Gerontol Geriatr 2008; 46: 203-9.
25. Chang AM, Halter JB. Aging and insulin secretion. Am J Physiol Endocrinol Metab 2003; 284: E7-12.
26. Lee S, Choi S, Kim HJ, Chung YS, Lee KW, Lee HC Et Al. Cutoff values of surrogate measures of insulin resistance for metabolic syndrome in Korean non-diabetic adults. J Korean Med Sci 2006; 21: 695-700.
27. GOBIERNO DE CHILE, MINISTERIO DE SALUD. Gobierno de Chile, Ministerio de Salud. I Encuesta Nacional de Salud, 2003. Disponible en: http://www.minsal.cl [Consultado el 12 de diciembre de 2008].