Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis

Tetrahedron

Volumn 70, Issue 42, 2014, Pages 7686-7690

  Zheng, Qingfei ^a   Wang, Shoufeng ^a   Liu, Wen ^a,b  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b Huzhou Center of Bio Synthetic Innovation   (China)

Author keywords

Alkaloid; Biosynthetic pathway; Chemo enzymatic synthesis; Peptide macrocycle; Thiostrepton

Indexed keywords

ALKALOID; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; QUINALDIC ACID; THIOSTREPTON;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CANCER CELL LINE; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; DRUG SYNTHESIS; ELIZABETHKINGIA MENINGOSEPTICA; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

EID: 84907946284     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2014.06.076     Document Type: Article

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