Characteristics and outcomes of patients hospitalized following pulmonary aspiration

Chest

Volumn 146, Issue 4, 2014, Pages 899-907

  Lee, Augustine ^a   Festic, Emir ^a   Park, Pauline K ^b   Raghavendran, Krishnan ^b   Dabbagh, Ousama ^c   Adesanya, Adebola ^d   Gajic, Ognjen ^e   Bartz, Raquel R ^f  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c University of Missouri   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MAYO CLINIC   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PROTON PUMP INHIBITOR;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGE DISTRIBUTION; ALCOHOL ABUSE; APACHE; ARTICLE; ARTIFICIAL VENTILATION; CAUCASIAN; COHORT ANALYSIS; CONTROLLED STUDY; COST BENEFIT ANALYSIS; DESCRIPTIVE RESEARCH; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GASTROESOPHAGEAL REFLUX; GLASGOW COMA SCALE; HIGH RISK POPULATION; HOSPITAL COST; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; NURSING HOME PATIENT; OBESITY; OUTCOME ASSESSMENT; PNEUMONIA; PROSPECTIVE STUDY; PULMONARY ASPIRATION; RISK FACTOR; SECONDARY ANALYSIS; SEX DIFFERENCE; AGED; LUNG INJURY; MIDDLE AGED; PNEUMONIA, ASPIRATION; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

ADULT; AGED; FEMALE; HOSPITAL MORTALITY; HOSPITALIZATION; HUMANS; LUNG INJURY; MALE; MIDDLE AGED; PNEUMONIA, ASPIRATION; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84907939297     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.13-3028     Document Type: Article

References (34)

1. Pepe PE, Potkin RT, Reus DH, Hudson LD, Carrico CJ . Clinical predictors of the adult respiratory distress syndrome . Am J Surg . 1982; 144 ( 1 ): 124 - 130 .
2. Fowler AA, Hamman RF, Good JT, et al . Adult respiratory distress syndrome: risk with common predispositions . Ann Intern Med . 1983; 98 ( 5 Pt 1 ): 593 - 597 .
3. Doyle RL, Szafl arski N, Modin GW, Wiener-Kronish JP, Matthay MA. Identification of patients with acute lung injury. Predictors of mortality . Am J Respir Crit Care Med . 1995; 152( 6 Pt 1): 1818- 1824.
4. Zilberberg MD, Epstein SK . Acute lung injury in the medical ICU: comorbid conditions, age, etiology, and hospital outcome . Am J Respir Crit Care Med . 1998; 157 ( 4 Pt 1 ): 1159 - 1164 .
5. Eisner MD, Thompson T, Hudson LD, et al; Acute Respiratory Distress Syndrome Network . Efficacy of low tidal volume ventilation in patients with diff erent clinical risk factors for acute lung injury and the acute respiratory distress syndrome . Am J Respir Crit Care Med . 2001; 164 ( 2 ): 231 - 236 .
6. Spragg RG, Bernard GR, Checkley W, et al . Beyond mortality: future clinical research in acute lung injury . Am J Respir Crit Care Med . 2010; 181 ( 10 ): 1121 - 1127 .
7. Gajic O, Dabbagh O, Park PK, et al; US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS). Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study . Am J Respir Crit Care Med . 2011; 183( 4): 462- 470.
8. Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury . N Engl J Med . 2005; 353( 16): 1685- 1693.
9. Teramoto S, Fukuchi Y, Sasaki H, Sato K, Sekizawa K, Matsuse T; Japanese Study Group on Aspiration Pulmonary Disease . High incidence of aspiration pneumonia in community- and hospital-acquired pneumonia in hospitalized patients: A multicenter, prospective study in Japan . J Am Geriatr Soc . 2008; 56 ( 3 ): 577 - 579 .
10. Marik PE . Aspiration pneumonitis and aspiration pneumonia . N Engl J Med . 2001; 344 ( 9 ): 665 - 671 .
11. Bernard GR, Artigas A, Brigham KL, et al . The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination . Am J Respir Crit Care Med . 1994; 149 ( 3 pt 1 ): 818 - 824 .
12. Ferguson ND, Fan E, Camporota L, et al . The Berlin definition of ARDS: An expanded rationale, justification, and supplementary material . Intensive Care Med . 2012; 38 ( 10 ): 1573 - 1582 .
13. Horan TC, Andrus M, Dudeck MA . CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting . Am J Infect Control . 2008; 36 ( 5 ): 309 - 332 .
14. Bohman JK, Kor DJ, Kashyap R, et al . Airway pepsin levels in otherwise healthy surgical patients receiving general anesthesia with endotracheal intubation . Chest . 2013; 143 ( 5 ): 1407 - 1413 .
15. Trinick R, Johnston N, Dalzell AM, McNamara PS . Reflux aspiration in children with neurodisability-a significant problem, but can we measure it? J Pediatr Surg . 2012; 47 ( 2 ): 291 - 298 .
16. Raghavendran K, Nemzek J, Napolitano LM, Knight PR . Aspiration-induced lung injury . Crit Care Med . 2011; 39 ( 4 ): 818 - 826 .
17. Warner MA, Warner ME, Weber JG . Clinical significance of pulmonary aspiration during the perioperative period . Anesthesiology . 1993; 78 ( 1 ): 56 - 62 .
18. Rotta AT, Shiley KT, Davidson BA, Helinski JD, Russo TA, Knight PR . Gastric acid and particulate aspiration injury inhibits pulmonary bacterial clearance . Crit Care Med . 2004; 32 ( 3 ): 747 - 754 .
19. Manno EM, Rabinstein AA, Wijdicks EF, et al . A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: A feasibility study . Crit Care . 2008; 12 ( 6 ): R138 .
20. Bice T, Li G, Malinchoc M, Lee AS, Gajic O . Incidence and risk factors of recurrent acute lung injury . Crit Care Med . 2011; 39 ( 5 ): 1069 - 1073 .
21. Knight PR, Rutter T, Tait AR, Coleman E, Johnson K . Pathogenesis of gastric particulate lung injury: A comparison and interaction with acidic pneumonitis . Anesth Analg . 1993; 77 ( 4 ): 754 - 760.
22. Raghavendran K, Davidson BA, Mullan BA, et al . Acid and particulateinduced aspiration lung injury in mice: Importance of MCP-1 . Am J Physiol Lung Cell Mol Physiol . 2005; 289 ( 1 ): L134 - L143.
23. Knight PR, Davidson BA, Nader ND, et al . Progressive, severe lung injury secondary to the interaction of insults in gastric aspiration . Exp Lung Res . 2004; 30 ( 7 ): 535 - 557 .
24. Eom CS, Jeon CY, Lim JW, Cho EG, Park SM, Lee KS. Use of acid-suppressive drugs and risk of pneumonia: A systematic review and meta-analysis . CMAJ . 2011; 183 ( 3 ): 310 - 319 .
25. Fox AJ, Lalloo UG, Belvisi MG, Bernareggi M, Chung KF, Barnes PJ . Bradykinin-evoked sensitization of airway sensory nerves: A mechanism for ACE-inhibitor cough . Nat Med . 1996; 2 ( 7 ): 814 - 817 .
26. Ebihara T, Sekizawa K, Ohrui T, Nakazawa H, Sasaki H . Angiotensinconverting enzyme inhibitor and danazol increase sensitivity of cough refl ex in female guinea pigs . Am J Respir Crit Care Med . 1996; 153 ( 2 ): 812 - 819 .
27. Yeo WW, Chadwick IG, Kraskiewicz M, Jackson PR, Ramsay LE . Resolution of ACE inhibitor cough: changes in subjective cough and responses to inhaled capsaicin, intradermal bradykinin and substance-P . Br J Clin Pharmacol . 1995; 40 ( 5 ): 423 - 429 .
28. Ohkubo T, Chapman N, Neal B, Woodward M, Omae T, Chalmers J; Perindopril Protection Against Recurrent Stroke Sutdy Collaborative Group . Eff ects of an angiotensin-converting enzyme inhibitor-based regimen on pneumonia risk . Am J Respir Crit Care Med . 2004; 169 ( 9 ): 1041 - 1045 .
29. Kikuchi R, Watabe N, Konno T, Mishina N, Sekizawa K, Sasaki H . High incidence of silent aspiration in elderly patients with community-acquired pneumonia . Am J Respir Crit Care Med . 1994; 150 ( 1 ): 251 - 253 .
30. Neubert H, Gale J, Muirhead D . Online high-flow peptide immunoaffinity enrichment and nanoflow LC-MS/MS: Assay development for total salivary pepsin/pepsinogen . Clin Chem . 2010; 56 ( 9 ): 1413 - 1423 .
31. Patel MB, McKenna JW, Alvarez JM, et al . Decreasing adrenergic or sympathetic hyperactivity aft er severe traumatic brain injury using propranolol and clonidine (DASH Aft er TBI Study): study protocol for a randomized controlled trial . Trials . 2012; 13 : 177 .
32. Pereira CT, Jeschke MG, Herndon DN . Beta-blockade in burns . Novartis Found Symp . 2007; 280 : 238 - 248 .
33. Prass K, Braun JS, Dirnagl U, Meisel C, Meisel A . Stroke propagates bacterial aspiration to pneumonia in a model of cerebral ischemia . Stroke . 2006; 37 ( 10 ): 2607 - 2612 .
34. Marik PE . Pulmonary aspiration syndromes . Curr Opin Pulm Med . 2011; 17 ( 3 ): 148 - 154 .