-
1
-
-
77953496625
-
The nf-kappab family of transcription factors and its regulation
-
Oeckinghaus A, Ghosh S (2009) The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 1(4):a000034.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
, Issue.4
, pp. a000034
-
-
Oeckinghaus, A.1
Ghosh, S.2
-
2
-
-
0036781052
-
Nf-kappab regulation in the immune system
-
Li Q, Verma IM (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2(10):725-734.
-
(2002)
Nat Rev Immunol
, vol.2
, Issue.10
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
3
-
-
84858726313
-
Regulation of cell death and autophagy by ikk and nf-κb: Critical mechanisms in immune function and cancer
-
Baldwin AS (2012) Regulation of cell death and autophagy by IKK and NF-κB: Critical mechanisms in immune function and cancer. Immunol Rev 246(1):327-345.
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 327-345
-
-
Baldwin, A.S.1
-
4
-
-
43749098070
-
Nf-kappab and cancer-identifying targets and mechanisms
-
Naugler WE, Karin M (2008) NF-kappaB and cancer-identifying targets and mechanisms. Curr Opin Genet Dev 18(1):19-26.
-
(2008)
Curr Opin Genet Dev
, vol.18
, Issue.1
, pp. 19-26
-
-
Naugler, W.E.1
Karin, M.2
-
5
-
-
84858744393
-
It takes two to tango: Iκbs, the multifunctional partners of nf-κb
-
Hinz M, Arslan SC, Scheidereit C (2012) It takes two to tango: IκBs, the multifunctional partners of NF-κB. Immunol Rev 246(1):59-76.
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 59-76
-
-
Hinz, M.1
Arslan, S.C.2
Scheidereit, C.3
-
6
-
-
84858734708
-
Nf-κb and chromatin: Ten years on the path from basic mechanisms to candidate drugs
-
Natoli G (2012) NF-κB and chromatin: Ten years on the path from basic mechanisms to candidate drugs. Immunol Rev 246(1):183-192.
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 183-192
-
-
Natoli, G.1
-
7
-
-
83855162723
-
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of nf-κb family dna binding
-
Siggers T, et al. (2012) Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat Immunol 13(1):95-102.
-
(2012)
Nat Immunol
, vol.13
, Issue.1
, pp. 95-102
-
-
Siggers, T.1
-
8
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill F (2009) Tumour necrosis factor and cancer. Nat Rev Cancer 9(5):361-371.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.5
, pp. 361-371
-
-
Balkwill, F.1
-
9
-
-
0028931441
-
Specific inhibition of relb/p52 transcriptional activity by the c-terminal domain of p100
-
Dobrzanski P, Ryseck RP, Bravo R (1995) Specific inhibition of RelB/p52 transcriptional activity by the C-terminal domain of p100. Oncogene 10(5):1003-1007.
-
(1995)
Oncogene
, vol.10
, Issue.5
, pp. 1003-1007
-
-
Dobrzanski, P.1
Ryseck, R.P.2
Bravo, R.3
-
10
-
-
84859998939
-
Control of nf-κb activity by proteolysis
-
Baud V, Derudder E (2011) Control of NF-κB activity by proteolysis. Curr Top Microbiol Immunol 349:97-114.
-
(2011)
Curr Top Microbiol Immunol
, vol.349
, pp. 97-114
-
-
Baud, V.1
Derudder, E.2
-
11
-
-
0037413709
-
Relb is required for peyer's patch development: Differential regulation of p52-relb by lymphotoxin and tnf
-
Yilmaz ZB, Weih DS, Sivakumar V, Weih F (2003) RelB is required for Peyer's patch development: Differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J 22(1):121-130.
-
(2003)
EMBO J
, vol.22
, Issue.1
, pp. 121-130
-
-
Yilmaz, Z.B.1
Weih, D.S.2
Sivakumar, V.3
Weih, F.4
-
12
-
-
0037931474
-
Relb/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: Critical roles for p100
-
Derudder E, et al. (2003) RelB/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: Critical roles for p100. J Biol Chem 278(26):23278-23284.
-
(2003)
J Biol Chem
, vol.278
, Issue.26
, pp. 23278-23284
-
-
Derudder, E.1
-
13
-
-
33846323310
-
A fourth ikappab protein within the nf-kappab signaling module
-
Basak S, et al. (2007) A fourth IkappaB protein within the NF-kappaB signaling module. Cell 128(2):369-381.
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 369-381
-
-
Basak, S.1
-
14
-
-
26844572062
-
Rela repression of relb activity induces selective gene activation downstream of tnf receptors
-
Jacque E, Tchenio T, Piton G, Romeo PH, Baud V (2005) RelA repression of RelB activity induces selective gene activation downstream of TNF receptors. Proc Natl Acad Sci USA 102(41):14635-14640.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.41
, pp. 14635-14640
-
-
Jacque, E.1
Tchenio, T.2
Piton, G.3
Romeo, P.H.4
Baud, V.5
-
15
-
-
78649670803
-
Classical nf-kappab activation negatively regulates noncanonical nf-kappab-dependent cxcl12 expression
-
Madge LA, May MJ (2010) Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression. J Biol Chem 285(49):38069-38077.
-
(2010)
J Biol Chem
, vol.285
, Issue.49
, pp. 38069-38077
-
-
Madge, L.A.1
May, M.J.2
-
16
-
-
45549105396
-
Stabilization of relb requires multidomain interactions with p100/p52
-
Fusco AJ, et al. (2008) Stabilization of RelB requires multidomain interactions with p100/p52. J Biol Chem 283(18):12324-12332.
-
(2008)
J Biol Chem
, vol.283
, Issue.18
, pp. 12324-12332
-
-
Fusco, A.J.1
-
17
-
-
0028817585
-
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of relb, a member of the nf-kappa b/rel family
-
Weih F, et al. (1995) Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Cell 80(2):331-340.
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 331-340
-
-
Weih, F.1
-
18
-
-
0029851721
-
Inducible activation of relb in fibroblasts
-
Olashaw NE (1996) Inducible activation of RelB in fibroblasts. J Biol Chem 271(48): 30307-30310.
-
(1996)
J Biol Chem
, vol.271
, Issue.48
, pp. 30307-30310
-
-
Olashaw, N.E.1
-
19
-
-
79251536527
-
Iκb kinase β regulates epithelium migration during corneal wound healing
-
Chen L, Meng Q, Kao W, Xia Y (2011) IκB kinase β regulates epithelium migration during corneal wound healing. PLoS ONE 6(1):e16132.
-
(2011)
PLoS ONE
, vol.6
, Issue.1
, pp. e16132
-
-
Chen, L.1
Meng, Q.2
Kao, W.3
Xia, Y.4
-
20
-
-
39049183044
-
Regulation and function of ikk and ikk-related kinases
-
Häcker H, Karin M (2006) Regulation and function of IKK and IKK-related kinases. Sci STKE 2006(357):re13.
-
(2006)
Sci STKE 2006
, Issue.357
, pp. re13
-
-
Häcker, H.1
Karin, M.2
-
21
-
-
34548076607
-
Interferon-gamma regulation of tnfalpha-induced matrix metalloproteinase 3 expression and migration of human glioma t98g cells
-
Cheng SM, Xing B, Li JC, Cheung BK, Lau AS (2007) Interferon-gamma regulation of TNFalpha-induced matrix metalloproteinase 3 expression and migration of human glioma T98G cells. Int J Cancer 121(6):1190-1196.
-
(2007)
Int J Cancer
, vol.121
, Issue.6
, pp. 1190-1196
-
-
Cheng, S.M.1
Xing, B.2
Li, J.C.3
Cheung, B.K.4
Lau, A.S.5
-
22
-
-
84869411578
-
Control of relb during dendritic cell activation integrates canonical and noncanonical nf-κb pathways
-
Shih VF, et al. (2012) Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways. Nat Immunol 13(12):1162-1170.
-
(2012)
Nat Immunol
, vol.13
, Issue.12
, pp. 1162-1170
-
-
Shih, V.F.1
-
23
-
-
84858735072
-
The noncanonical nf-κb pathway
-
Sun SC (2012) The noncanonical NF-κB pathway. Immunol Rev 246(1):125-140.
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 125-140
-
-
Sun, S.C.1
-
24
-
-
58449136060
-
The alternative nf-kb activation pathway and cancer: Friend or foe?
-
Baud V, Jacque E (2008) [The alternative NF-kB activation pathway and cancer: Friend or foe?] Med Sci (Paris) 24(12):1083-1088.
-
(2008)
Med Sci (Paris)
, vol.24
, Issue.12
, pp. 1083-1088
-
-
Baud, V.1
Jacque, E.2
-
25
-
-
24944489952
-
Stimulus specificity of gene expression programs determined by temporal control of ikk activity
-
Werner SL, Barken D, Hoffmann A (2005) Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309(5742):1857-1861.
-
(2005)
Science
, vol.309
, Issue.5742
, pp. 1857-1861
-
-
Werner, S.L.1
Barken, D.2
Hoffmann, A.3
-
26
-
-
80052734912
-
A20-binding inhibitor of nuclear factor-kappab (nf-kappab)- 2 (abin-2) is an activator of inhibitor of nf-kappab (ikappab) kinase alpha (ikkalpha)- mediated nf-kappab transcriptional activity
-
Leotoing L, et al. (2011) A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)- 2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)- mediated NF-kappaB transcriptional activity. J Biol Chem 286(37):32277-32288.
-
(2011)
J Biol Chem
, vol.286
, Issue.37
, pp. 32277-32288
-
-
Leotoing, L.1
-
27
-
-
33750457370
-
Post-translational modifications regulating the activity and function of the nuclear factor kappa b pathway
-
Perkins ND (2006) Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene 25(51):6717-6730.
-
(2006)
Oncogene
, vol.25
, Issue.51
, pp. 6717-6730
-
-
Perkins, N.D.1
-
28
-
-
17844386319
-
Ikkalpha limits macrophage nf-kappab activation and contributes to the resolution of inflammation
-
Lawrence T, Bebien M, Liu GY, Nizet V, Karin M (2005) IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 434(7037):1138-1143.
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
29
-
-
0032589462
-
Ikappab kinases phosphorylate nf-kappab p65 subunit on serine 536 in the transactivation domain
-
Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W (1999) IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem 274(43):30353-30356.
-
(1999)
J Biol Chem
, vol.274
, Issue.43
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
30
-
-
80052208984
-
The role of rela (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration
-
Msaki A, et al. (2011) The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration. Mol Biol Cell 22(17):3032-3040.
-
(2011)
Mol Biol Cell
, vol.22
, Issue.17
, pp. 3032-3040
-
-
Msaki, A.1
-
31
-
-
17144422434
-
Regulation of nf-kappab and p53 through activation of atr and chk1 by the arf tumour suppressor
-
Rocha S, Garrett MD, Campbell KJ, Schumm K, Perkins ND (2005) Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor. EMBO J 24(6):1157-1169.
-
(2005)
EMBO J
, vol.24
, Issue.6
, pp. 1157-1169
-
-
Rocha, S.1
Garrett, M.D.2
Campbell, K.J.3
Schumm, K.4
Perkins, N.D.5
-
32
-
-
84859430011
-
Fbxw7α- And gsk3-mediated degradation of p100 is a prosurvival mechanism in multiple myeloma
-
Busino L, et al. (2012) Fbxw7α- And GSK3-mediated degradation of p100 is a prosurvival mechanism in multiple myeloma. Nat Cell Biol 14(4):375-385.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.4
, pp. 375-385
-
-
Busino, L.1
-
33
-
-
9144275033
-
Activation of ikkalpha target genes depends on recognition of specific kappab binding sites by relb:p52 dimers
-
Bonizzi G, et al. (2004) Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J 23(21):4202-4210.
-
(2004)
EMBO J
, vol.23
, Issue.21
, pp. 4202-4210
-
-
Bonizzi, G.1
-
34
-
-
80052282195
-
Malt1-dependent relb cleavage promotes canonical nf-kappab activation in lymphocytes and lymphoma cell lines
-
Hailfinger S, et al. (2011) Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines. Proc Natl Acad Sci USA 108(35):14596-14601.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.35
, pp. 14596-14601
-
-
Hailfinger, S.1
-
35
-
-
0035819033
-
Signal-specific and phosphorylation-dependent relb degradation: A potential mechanism of nf-kappab control
-
Marienfeld R, et al. (2001) Signal-specific and phosphorylation-dependent RelB degradation: A potential mechanism of NF-kappaB control. Oncogene 20(56):8142-8147.
-
(2001)
Oncogene
, vol.20
, Issue.56
, pp. 8142-8147
-
-
Marienfeld, R.1
-
36
-
-
42149185026
-
Daxx represses relb target promoters via dna methyltransferase recruitment and dna hypermethylation
-
Puto LA, Reed JC (2008) Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation. Genes Dev 22(8):998-1010.
-
(2008)
Genes Dev
, vol.22
, Issue.8
, pp. 998-1010
-
-
Puto, L.A.1
Reed, J.C.2
-
37
-
-
34047095373
-
Oestrogen signalling inhibits invasive phenotype by repressing relb and its target bcl2
-
Wang X, et al. (2007) Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2. Nat Cell Biol 9(4):470-478.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.4
, pp. 470-478
-
-
Wang, X.1
-
38
-
-
65949109942
-
Relb enhances prostate cancer growth: Implications for the role of the nuclear factor-kappab alternative pathway in tumorigenicity
-
Xu Y, et al. (2009) RelB enhances prostate cancer growth: Implications for the role of the nuclear factor-kappaB alternative pathway in tumorigenicity. Cancer Res 69(8):3267-3271.
-
(2009)
Cancer Res
, vol.69
, Issue.8
, pp. 3267-3271
-
-
Xu, Y.1
-
39
-
-
84874362151
-
The nf-κb relb protein is an oncogenic driver of mesenchymal glioma
-
Lee DW, et al. (2013) The NF-κB RelB protein is an oncogenic driver of mesenchymal glioma. PLoS ONE 8(2):e57489.
-
(2013)
PLoS ONE
, vol.8
, Issue.2
, pp. e57489
-
-
Lee, D.W.1
-
40
-
-
77950931419
-
Matrix metal oproteinases: Regulators of the tumor microenvironment
-
Kessenbrock K, Plaks V, Werb Z (2010) Matrix metal oproteinases: Regulators of the tumor microenvironment. Cell 141(1):52-67.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
|