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Volumn 12, Issue 1, 2014, Pages

Cx43 phosphorylation on S279/282 and intercellular communication are regulated by IP3/IP3 receptor signaling

Author keywords

Connexin 43; Gap junction; Inositol 1,4,5 trisphosphate receptor; Intercellular communication; Serine 279 282 phosphorylation; Ventricular myocyte

Indexed keywords

6 CARBOXYFLUORESCEIN; ADENOSINE TRIPHOSPHATE; ALANINE; CONNEXIN 43; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR 1; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR 2; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR 3; SERINE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; INOSITOL 1,4,5 TRISPHOSPHATE;

EID: 84907931364     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/s12964-014-0058-6     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 1942503184 scopus 로고    scopus 로고
    • Gap junctions and connexin-interacting proteins
    • 15094344
    • Gap junctions and connexin-interacting proteins. BN Giepmans, Cardiovasc Res 2004 62 233 245 10.1016/j.cardiores.2003.12.009 15094344
    • (2004) Cardiovasc Res , vol.62 , pp. 233-245
    • Giepmans, B.N.1
  • 2
    • 0037382614 scopus 로고    scopus 로고
    • Beyond the gap: Functions of unpaired connexon channels
    • 12671651
    • Beyond the gap: functions of unpaired connexon channels. DA Goodenough, DL Paul, Nat Rev Mol Cell Biol 2003 4 285 294 10.1038/nrm1072 12671651
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 285-294
    • Goodenough, D.A.1    Paul, D.L.2
  • 4
    • 0032942363 scopus 로고    scopus 로고
    • Inhibition of inositol (1,4,5)trisphosphate generation by endothelin-1 during postischemic reperfusion: A novel antiarrhythmic mechanism
    • Inhibition of inositol (1,4,5)trisphosphate generation by endothelin-1 during postischemic reperfusion: A novel antiarrhythmic mechanism. EA Woodcock, N Reyes, AN Jacobsen, XJ Du, Circ 1999 99 823 828 10.1161/01.CIR.99.6.823
    • (1999) Circ , vol.99 , pp. 823-828
    • Woodcock, E.A.1    Reyes, N.2    Jacobsen, A.N.3    Du, X.J.4
  • 5
    • 33744455507 scopus 로고    scopus 로고
    • Cardiac ischemia and uncoupling: Gap junctions in ischemia and infarction
    • 16646592
    • Cardiac ischemia and uncoupling: gap junctions in ischemia and infarction. S Dhein, Adv Cardiol 2006 42 198 212 10.1159/000092570 16646592
    • (2006) Adv Cardiol , vol.42 , pp. 198-212
    • Dhein, S.1
  • 6
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • 16492141
    • Life cycle of connexins in health and disease. DW Laird, Biochem J 2006 394 527 543 10.1042/BJ20051922 16492141
    • (2006) Biochem J , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 7
    • 8444245596 scopus 로고    scopus 로고
    • Connexins and cell signaling in development and disease
    • 15473861
    • Connexins and cell signaling in development and disease. CJ Wei, X Xu, CW Lo, Annu Rev Cell Dev Biol 2004 20 811 838 10.1146/annurev.cellbio.19.111301.144309 15473861
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 811-838
    • Wei, C.J.1    Xu, X.2    Lo, C.W.3
  • 8
    • 58149092631 scopus 로고    scopus 로고
    • Connexin-caused genetic diseases and corresponding mouse models
    • 18831677
    • Connexin-caused genetic diseases and corresponding mouse models. R Dobrowolski, K Willecke, Antioxid Redox Signal 2009 11 283 295 10.1089/ars.2008.2128 18831677
    • (2009) Antioxid Redox Signal , vol.11 , pp. 283-295
    • Dobrowolski, R.1    Willecke, K.2
  • 9
    • 0031830342 scopus 로고    scopus 로고
    • Structure of cardiac gap junction intercellular channels
    • 9615440
    • Structure of cardiac gap junction intercellular channels. M Yeager, J Struct Biol 1998 121 231 245 10.1006/jsbi.1998.3972 9615440
    • (1998) J Struct Biol , vol.121 , pp. 231-245
    • Yeager, M.1
  • 10
    • 33746566071 scopus 로고    scopus 로고
    • Phosphorylation selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation
    • 16709897
    • Phosphorylation selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation. NS Heyman, PD Lampe, M Janis Burt, Circ Res 2006 98 1498 1505 10.1161/01.RES.0000227572.45891.2c 16709897
    • (2006) Circ Res , vol.98 , pp. 1498-1505
    • Heyman, N.S.1    Lampe, P.D.2    Janis Burt, M.3
  • 11
    • 0032502785 scopus 로고    scopus 로고
    • Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase
    • 9535909
    • Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase. BJ Warn-Cramer, GT Cottrell, JM Burt, AF Lau, J Biol Chem 1998 273 9188 9196 10.1074/jbc.273.15.9188 9535909
    • (1998) J Biol Chem , vol.273 , pp. 9188-9196
    • Warn-Cramer, B.J.1    Cottrell, G.T.2    Burt, J.M.3    Lau, A.F.4
  • 12
    • 48449089173 scopus 로고    scopus 로고
    • Connexin 43 in LA-25 cells with active v-src is phosphorylated on Y247, Y265, S262, S279/282, and S368 via multiple signaling pathways
    • 18649180
    • Connexin 43 in LA-25 cells with active v-src is phosphorylated on Y247, Y265, S262, S279/282, and S368 via multiple signaling pathways. JL Solan, PD Lampe, Cell Commun Adhes 2008 15 75 84 10.1080/15419060802014016 18649180
    • (2008) Cell Commun Adhes , vol.15 , pp. 75-84
    • Solan, J.L.1    Lampe, P.D.2
  • 13
    • 39749165131 scopus 로고    scopus 로고
    • Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1
    • 18056766
    • Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1. AF Bruce, S Rothery, E Dupont, NJ Severs, Cardiovasc Res 2008 77 757 765 10.1093/cvr/cvm083 18056766
    • (2008) Cardiovasc Res , vol.77 , pp. 757-765
    • Bruce, A.F.1    Rothery, S.2    Dupont, E.3    Severs, N.J.4
  • 14
    • 0035921428 scopus 로고    scopus 로고
    • V-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication
    • 11514593
    • V-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication. R Lin, BJ Warn-Cramer, WE Kurata, AF Lau, J Cell Biol 2001 154 815 827 10.1083/jcb.200102027 11514593
    • (2001) J Cell Biol , vol.154 , pp. 815-827
    • Lin, R.1    Warn-Cramer, B.J.2    Kurata, W.E.3    Lau, A.F.4
  • 15
    • 84883161814 scopus 로고    scopus 로고
    • Effects of phosphorylation on the structure and backbone dynamics of the intrinsically disordered Connexin43 carboxyl-terminal domain
    • 23828237
    • Effects of phosphorylation on the structure and backbone dynamics of the intrinsically disordered Connexin43 carboxyl-terminal domain. R Grosely, JL Kopanic, S Nabors, F Kieken, G Spagnol, M Al-Mugotir, S Zach, PL Sorgen, J Biol Chem 2013 288 24857 24870 10.1074/jbc.M113.454389 23828237
    • (2013) J Biol Chem , vol.288 , pp. 24857-24870
    • Grosely, R.1    Kopanic, J.L.2    Nabors, S.3    Kieken, F.4    Spagnol, G.5    Al-Mugotir, M.6    Zach, S.7    Sorgen, P.L.8
  • 18
    • 38149127085 scopus 로고    scopus 로고
    • 2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes
    • 17583790
    • 2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes. D Luo, D Yang, X Lan, K Li, X Li, J Chen, Y Zhang, RP Xiao, Q Han, H Cheng, Cell Calcium 2008 43 165 174 10.1016/j.ceca.2007.04.017 17583790
    • (2008) Cell Calcium , vol.43 , pp. 165-174
    • Luo, D.1    Yang, D.2    Lan, X.3    Li, K.4    Li, X.5    Chen, J.6    Zhang, Y.7    Xiao, R.P.8    Han, Q.9    Cheng, H.10
  • 19
    • 80053572635 scopus 로고    scopus 로고
    • Distribution and functional role of inositol 1,4,5-trisphosphate receptors in mouse sinoatrial node
    • 21852551
    • Distribution and functional role of inositol 1,4,5-trisphosphate receptors in mouse sinoatrial node. YK Ju, J Liu, BH Lee, D Lai, EA Woodcock, M Lei, MB Cannell, DG Allen, Circ Res 2011 109 848 857 10.1161/CIRCRESAHA.111.243824 21852551
    • (2011) Circ Res , vol.109 , pp. 848-857
    • Ju, Y.K.1    Liu, J.2    Lee, B.H.3    Lai, D.4    Woodcock, E.A.5    Lei, M.6    Cannell, M.B.7    Allen, D.G.8
  • 20
    • 0027461948 scopus 로고
    • Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes
    • 8381433
    • Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes. Y Kijima, A Saito, TL Jetton, MA Magnuson, S Fleischer, J Biol Chem 1993 268 3499 3506 8381433
    • (1993) J Biol Chem , vol.268 , pp. 3499-3506
    • Kijima, Y.1    Saito, A.2    Jetton, T.L.3    Magnuson, M.A.4    Fleischer, S.5
  • 21
    • 59149101575 scopus 로고    scopus 로고
    • 2+ communication
    • 18946029
    • 2+ communication. BE Isakson, J Cell Sci 2008 121 3664 3673 10.1242/jcs.037481 18946029
    • (2008) J Cell Sci , vol.121 , pp. 3664-3673
    • Isakson, B.E.1
  • 22
    • 33845926094 scopus 로고    scopus 로고
    • Signaling protein in the axoglial apparatus of sciatic nerve node of Ranvier
    • 17091480
    • Signaling protein in the axoglial apparatus of sciatic nerve node of Ranvier. JC Toews, V Schram, SH Weerth, GA Mignery, JT Russell, Glia 2007 55 202 213 10.1002/glia.20448 17091480
    • (2007) Glia , vol.55 , pp. 202-213
    • Toews, J.C.1    Schram, V.2    Weerth, S.H.3    Mignery, G.A.4    Russell, J.T.5
  • 23
    • 0032576553 scopus 로고    scopus 로고
    • Reduced reperfusion-induced Ins(1,4,5)P3 generation and arrhythmias in hearts expressing constitutively active alpha1B-adrenergic receptors
    • 9851940
    • Reduced reperfusion-induced Ins(1,4,5)P3 generation and arrhythmias in hearts expressing constitutively active alpha1B-adrenergic receptors. SN Harrison, DJ Autelitano, BH Wang, C Milano, XJ Du, EA Woodcock, Circ Res 1998 83 1232 1240 10.1161/01.RES.83.12.1232 9851940
    • (1998) Circ Res , vol.83 , pp. 1232-1240
    • Harrison, S.N.1    Autelitano, D.J.2    Wang, B.H.3    Milano, C.4    Du, X.J.5    Woodcock, E.A.6
  • 24
    • 4944253254 scopus 로고    scopus 로고
    • Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels
    • 15358666
    • Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels. MS Turner, GA Haywood, P Andreka, L You, PE Martin, WH Evans, KA Webster, NH Bishopric, Circ Res 2004 95 726 733 10.1161/01.RES.0000144805.11519.1e 15358666
    • (2004) Circ Res , vol.95 , pp. 726-733
    • Turner, M.S.1    Haywood, G.A.2    Andreka, P.3    You, L.4    Martin, P.E.5    Evans, W.H.6    Webster, K.A.7    Bishopric, N.H.8
  • 27
    • 45449108056 scopus 로고    scopus 로고
    • 2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries
    • 18191200
    • 2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries. Y Kansui, CJ Garland, KA Dora, Cell Calcium 2008 44 135 146 10.1016/j.ceca.2007.11.012 18191200
    • (2008) Cell Calcium , vol.44 , pp. 135-146
    • Kansui, Y.1    Garland, C.J.2    Dora, K.A.3
  • 28
    • 78049255782 scopus 로고    scopus 로고
    • Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels
    • 20855598
    • Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels. X Wang, ML Veruki, NV Bukoreshtliev, E Hartveit, HH Gerdes, Proc Natl Acad Sci U S A 2010 107 17194 17199 10.1073/pnas.1006785107 20855598
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17194-17199
    • Wang, X.1    Veruki, M.L.2    Bukoreshtliev, N.V.3    Hartveit, E.4    Gerdes, H.H.5
  • 29
    • 34250195774 scopus 로고    scopus 로고
    • Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes, novel basis for modulation of cardiac conduction by gene therapy
    • 17495226
    • Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes, novel basis for modulation of cardiac conduction by gene therapy. E Kizana, CY Chang, E Cingolani, GA Ramirez-Correa, RB Sekar, MR Abraham, SL Ginn, L Tung, IE Alexander, E Marban, Circ Res 2007 100 1597 1604 10.1161/CIRCRESAHA.106.144956 17495226
    • (2007) Circ Res , vol.100 , pp. 1597-1604
    • Kizana, E.1    Chang, C.Y.2    Cingolani, E.3    Ramirez-Correa, G.A.4    Sekar, R.B.5    Abraham, M.R.6    Ginn, S.L.7    Tung, L.8    Alexander, I.E.9    Marban, E.10
  • 30
    • 0022535332 scopus 로고
    • A fluorescence photobleaching assay of gap junction-mediated communication between human cells
    • 3961495
    • A fluorescence photobleaching assay of gap junction-mediated communication between human cells. MH Wade, JE Trosko, M Schindler, Science 1986 232 525 528 10.1126/science.3961495 3961495
    • (1986) Science , vol.232 , pp. 525-528
    • Wade, M.H.1    Trosko, J.E.2    Schindler, M.3
  • 31
    • 84869409999 scopus 로고    scopus 로고
    • Regulation of gap-junctional communication between cumulus cells during in vitro maturation in swine, a gap-FRAP study
    • Regulation of gap-junctional communication between cumulus cells during in vitro maturation in swine, a gap-FRAP study. NW Santiquet, Y Develle, A Laroche, C Robert, FJ Richard, Biol Reproduction 2012 87 1 8 10.1095/biolreprod.112.099754
    • (2012) Biol Reproduction , vol.87 , pp. 1-8
    • Santiquet, N.W.1    Develle, Y.2    Laroche, A.3    Robert, C.4    Richard, F.J.5
  • 32
    • 33344466696 scopus 로고    scopus 로고
    • Alterations of phosphorylation state of connexin 43 during hypoxia and reoxygenation are associated with cardiac function
    • 16314445
    • Alterations of phosphorylation state of connexin 43 during hypoxia and reoxygenation are associated with cardiac function. S Matsushita, H Kurihara, M Watanabe, T Okada, T Sakai, A Amano, J Histochem Cytochem 2006 54 343 353 10.1369/jhc.4A6611.2005 16314445
    • (2006) J Histochem Cytochem , vol.54 , pp. 343-353
    • Matsushita, S.1    Kurihara, H.2    Watanabe, M.3    Okada, T.4    Sakai, T.5    Amano, A.6
  • 33
    • 42149125581 scopus 로고    scopus 로고
    • Mimetic peptides as blockers of connexin channel-facilitated intercellular communication
    • 18392994
    • Mimetic peptides as blockers of connexin channel-facilitated intercellular communication. WH Evans, L Leybaert, Cell Commun Adhes 2007 14 265 273 10.1080/15419060801891034 18392994
    • (2007) Cell Commun Adhes , vol.14 , pp. 265-273
    • Evans, W.H.1    Leybaert, L.2
  • 34
    • 0033135290 scopus 로고    scopus 로고
    • Selective inhibition of gap junction channel activity by synthetic peptides
    • 10200417
    • Selective inhibition of gap junction channel activity by synthetic peptides. BR Kwak, HJ Jongsma, J Physiol 1999 516 679 685 10.1111/j.1469-7793.1999.0679u.x 10200417
    • (1999) J Physiol , vol.516 , pp. 679-685
    • Kwak, B.R.1    Jongsma, H.J.2
  • 35
    • 0029838641 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin43 epitopes in cardiac myocytes
    • 8831488
    • Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin43 epitopes in cardiac myocytes. BW Doble, Y Chen, DG Bosc, DW Litchfield, E Kardami, Circ Res 1996 79 647 658 10.1161/01.RES.79.4.647 8831488
    • (1996) Circ Res , vol.79 , pp. 647-658
    • Doble, B.W.1    Chen, Y.2    Bosc, D.G.3    Litchfield, D.W.4    Kardami, E.5
  • 36
    • 31844445153 scopus 로고    scopus 로고
    • Quantitative determination of gap junction intercellular communication by scrape loading and image analysis
    • 10830616
    • Quantitative determination of gap junction intercellular communication by scrape loading and image analysis. H Opsahl, E Rivedal, Cell Adhes Commun 2000 7 367 375 10.3109/15419060009109019 10830616
    • (2000) Cell Adhes Commun , vol.7 , pp. 367-375
    • Opsahl, H.1    Rivedal, E.2
  • 37
    • 84864368103 scopus 로고    scopus 로고
    • Phosphorylation of serine residues in the C-terminal cytoplasmic tail of connexin43 regulates proliferation of ovarian granulosa cells
    • 22729691
    • Phosphorylation of serine residues in the C-terminal cytoplasmic tail of connexin43 regulates proliferation of ovarian granulosa cells. PW Dyce, RP Norris, PD Lampe, GM Kidder, J Membr Biol 2012 245 291 301 10.1007/s00232-012-9450-6 22729691
    • (2012) J Membr Biol , vol.245 , pp. 291-301
    • Dyce, P.W.1    Norris, R.P.2    Lampe, P.D.3    Kidder, G.M.4
  • 38
  • 39
    • 0037646985 scopus 로고    scopus 로고
    • Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing measurement of single-cell membrane currents in undissociated cells
    • 12626431
    • Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing measurement of single-cell membrane currents in undissociated cells. EG Harks, JP Camina, PH Peters, DL Ypey, WJ Scheenen, EJ van Zoelen, AP Theuvenet, FASEB J 2003 17 941 943 12626431
    • (2003) FASEB J , vol.17 , pp. 941-943
    • Harks, E.G.1    Camina, J.P.2    Peters, P.H.3    Ypey, D.L.4    Scheenen, W.J.5    Van Zoelen, E.J.6    Theuvenet, A.P.7
  • 40
    • 49149093447 scopus 로고    scopus 로고
    • Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
    • 18636092
    • Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites. J Chen, L Pan, Z Wei, Y Zhao, M Zhang, EMBO J 2008 27 2113 2123 10.1038/emboj.2008.138 18636092
    • (2008) EMBO J , vol.27 , pp. 2113-2123
    • Chen, J.1    Pan, L.2    Wei, Z.3    Zhao, Y.4    Zhang, M.5
  • 41
    • 37249083141 scopus 로고    scopus 로고
    • Phosphorylation of Cx43 at S365 is a gatekeeper event that changes the structure of Cx43 and prevents downregulation by PKC
    • 18086922
    • Phosphorylation of Cx43 at S365 is a gatekeeper event that changes the structure of Cx43 and prevents downregulation by PKC. JL Solan, L Marquez-Rosado, PL Sorgen, PJ Thornton, PR Gafken, PD Lampe, J Cell Biol 2007 179 1301 1309 10.1083/jcb.200707060 18086922
    • (2007) J Cell Biol , vol.179 , pp. 1301-1309
    • Solan, J.L.1    Marquez-Rosado, L.2    Sorgen, P.L.3    Thornton, P.J.4    Gafken, P.R.5    Lampe, P.D.6
  • 42
    • 84875156443 scopus 로고    scopus 로고
    • Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells
    • Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells. KE Johnson, S Mitra, P Katoch, LS Kelsey, KR Johnson, PP Mehta, MBoC 2013 24 715 733
    • (2013) MBoC , vol.24 , pp. 715-733
    • Johnson, K.E.1    Mitra, S.2    Katoch, P.3    Kelsey, L.S.4    Johnson, K.R.5    Mehta, P.P.6
  • 43
    • 0036945719 scopus 로고    scopus 로고
    • Localization of sodium channels in intercalated disks modulates cardiac conduction
    • 12480819
    • Localization of sodium channels in intercalated disks modulates cardiac conduction. JP Kucera, S Rohr, Y Rudy, Circ Res 2002 91 1176 1182 10.1161/01.RES.0000046237.54156.0A 12480819
    • (2002) Circ Res , vol.91 , pp. 1176-1182
    • Kucera, J.P.1    Rohr, S.2    Rudy, Y.3
  • 45
    • 84866022277 scopus 로고    scopus 로고
    • Cx43 associates with Na(v)1.5 in the cardiomyocyte perinexus
    • 22811280
    • Cx43 associates with Na(v)1.5 in the cardiomyocyte perinexus. JM Rhett, EL Ongstad, J Jourdan, RG Gourdie, J Membr Biol 2012 245 411 422 10.1007/s00232-012-9465-z 22811280
    • (2012) J Membr Biol , vol.245 , pp. 411-422
    • Rhett, J.M.1    Ongstad, E.L.2    Jourdan, J.3    Gourdie, R.G.4


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