Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: Novel basis for modulation of cardiac conduction by gene therapy

Circulation Research

Volumn 100, Issue 11, 2007, Pages 1597-1604

  Kizana, Eddy ^a,c   Chang, Connie Y ^b,c   Cingolani, Eugenio ^c   Ramirez Correa, Genaro A ^c   Sekar, Rajesh B ^b   Abraham, M Roselle ^c   Ginn, Samantha L ^a   Tung, Leslie ^b   Alexander, Ian E ^a   Marbán, Eduardo ^c,d  

^a CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^b Johns Hopkins University   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d NONE   (United States)

Author keywords

Connexin43; Gap junction; Gene transfer

Indexed keywords

CONNEXIN 43; LENTIVIRUS VECTOR;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; FEMALE; FLUORESCENCE ANALYSIS; GAP JUNCTION; GENE THERAPY; GENE TRANSFER; GENETIC CODE; HEART CONDUCTION; HEART MUSCLE CELL; HEART VENTRICLE; HUMAN; HUMAN CELL; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM SIGNALING; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CONNEXIN 43; FLUORESCENT DYES; GAP JUNCTIONS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, DOMINANT; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEART CONDUCTION SYSTEM; HEART VENTRICLES; HUMANS; LENTIVIRUS; MUTAGENESIS, SITE-DIRECTED; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION;

EID: 34250195774     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.106.144956     Document Type: Article

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