FGF8 activates proliferation and migration in mouse post-natal oligodendrocyte progenitor cells

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Cruz Martinez, Pablo ^a   Martinez Ferre, Almudena ^a   Jaramillo Merchán, Jesus ^a   Estirado, Alicia ^a   Martinez, Salvador ^a,b   Jones, Jonathan ^a  

^a INSTITUTO DE NEUROCIENCIAS   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; FIBROBLAST GROWTH FACTOR 8; HEPARIN; MATRIGEL; MORPHOGEN; PROTEIN NG2; PROTEIN PDGFR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; CULTURE MEDIUM; DEMYELINATING DISEASE; EMBRYO DEVELOPMENT; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; OLIGODENDROCYTE PROGENITOR CELL; PERINATAL PERIOD; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REMYELINIZATION; STEM CELL; UPREGULATION; ANIMAL; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; DEMYELINATING DISEASES; DRUG EFFECTS; GENETICS; METABOLISM; NEURAL STEM CELL; OLIGODENDROGLIA; STEM CELL TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; DEMYELINATING DISEASES; FIBROBLAST GROWTH FACTOR 8; MICE; NEURAL STEM CELLS; OLIGODENDROGLIA; STEM CELL TRANSPLANTATION;

EID: 84907908410     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108241     Document Type: Article

References (53)

1. Steinman L (1996) Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85: 299-302.
2. Kohler W (2010) Leukodystrophies with late disease onset: an update. Curr Opin Neurol 23: 234-241.
3. Aktas O, Kieseier B, Hartung HP (2010) Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis. Trends Neurosci 33: 140-152.
4. Nave KA (2010) Myelination and support of axonal integrity by glia. Nature 468: 244-252.
5. Nishiyama A, Komitova M, Suzuki R, Zhu X (2009) Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat Rev Neurosci 10: 9-22.
6. Menn B, Garcia-Verdugo JM, Yaschine C, Gonzalez-Perez O, Rowitch D, et al. (2006) Origin of oligodendrocytes in the subventricular zone of the adult brain. J Neurosci 26: 7907-7918.
7. Sellers DL, Maris DO, Horner PJ (2009) Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury. J Neurosci 29: 6722-6733.
8. Chari DM, Crang AJ, Blakemore WF (2003) Decline in rate of colonization of oligodendrocyte progenitor cell (OPC)-depleted tissue by adult OPCs with age. J Neuropathol Exp Neurol 62: 908-916.
9. Chari DM, Huang WL, Blakemore WF (2003) Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. J Neurosci Res 73: 787-793.
10. Williams A, Piaton G, Aigrot MS, Belhadi A, Théaudin M, et al. (2007) Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis? Brain 130: 2554-2565.
11. Kuhlmann T, Miron V, Cui Q, Wegner C, Antel J, et al. (2008) Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 131: 1749-1758.
12. Irvine KA, Blakemore WF (2008) Remyelination protects axons from demyelination-associated axon degeneration. Brain 131: 1464-1477.
13. Jaramillo-Merchán J, Jones J, Ivorra JL, Pastor D, Viso-León MC, et al. (2013) Mesenchymal stromal-cell transplants induce oligodendrocyte progenitor migration and remyelination in a chronic demyelination model. Cell Death and Disease 4: e779.
14. Eriksson AE, Cousens LS, Weaver LH, Matthews BW (1991) Three-dimensional structure of human basic fibroblast growth factor. Proc Natl Acad Sci USA 88: 3441-3445.
15. Itoh N, Ornitz DM (2004) Evolution of the FGF and FGFR gene families. Trends in Genetics 20: 563-569.
16. Mohammadi M, Olsen SK, Ibrahimi OA (2005) Structural basis for fibroblast growth factor receptor activation. Cytokine Growth Factor Rev 16: 107-137.
17. Gotoh N (2008) Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins. Cancer Sci 99: 1319-1325.
18. Mitew S, Hay CM, Peckham H, Xiao J, Koenning M, et al. (2013) Mechanisms regulating the development of oligodendrocytes and central nervous system myelin. Neuroscience.
19. Bottcher RT, Niehrs C (2005) Fibroblast growth factor signaling during early vertebrate development. Endocr Rev 26: 63-77.
20. Thisse B, Thisse C (2005) Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol 287: 390-402.
21. Turner N, Grose R (2010) Fibroblast growth factor signalling: from development to cancer. Nature Rev Cancer 10: 116-129.
22. Chandran S, Kato H, Gerreli D, Compston A, Svendsen CN, et al. (2003) FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 130: 6599-6609.
23. Furusho M, Kaga Y, Ishii A, Hébert JM, Bansal R (2011) Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. J Neurosci 31: 5055-5066.
24. Crossley PH, Martin GR (1995) The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121: 439-451.
25. Crossley PH, Martinez S, Martin GR (1996) Midbrain development induced by FGF8 in the chick embryo. Nature 380: 66-68.
26. Reifers F, Böhli H, Walsh EC, Crossley PH, Stainier DY, et al. (1998) Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125: 2381-2395.
27. Partanen J (2007) FGF signalling pathways in development of the midbrain and anterior hindbrain. J Neurochem 101: 1185-1193.
28. Nakamura H, Sato T, Suzuki-Hirano A (2008) Isthmus organizer for mesencephalon and metencephalon. Dev Growth Differ 50: S113-118.
29. Storm EE, Garel S, Borello U, Hebert JM, Martinez S, et al. (2006) Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development 133: 1831-1844.
30. Martinez-Ferre A, Martinez S (2009) The development of the thalamic motor learning area is regulated by Fgf8 expression. J Neurosci 29: 13389-13400.
31. Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, et al. (1996) Receptor specificity of the fibroblast growth factor family. J Biol Chem 271: 15292-15297.
32. Kouhara H, Koga M, Kasayama S, Tanaka A, Kishimoto T, et al. (1994) Transforming activity of a newly cloned androgen-induced growth factor Oncogene 9: 455-462.
33. Christen B, Slack JM (1999) Spatial response to fibroblast growth factor signalling in Xenopus embryos. Development 126: 119-25.
34. Corson L, Yamanaka Y, Lai K, Rossant J (2003) Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130: 4527-4537.
35. Tsang M, Dawid IB (2004) Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci STKE 228: pe17.
36. Lunn JS, Fishwick KJ, Halley PA, Storey KG (2007) A spatial and temporal map of FGF/Erk1/2 activity and response repertoires in the early chick embryo. Dev Biol 302: 536-552.
37. Yang Z, Watanabe M, Nishiyama A (2005) Optimization of oligodendrocyte progenitor cell culture method for enhanced survival. J Neurosci Methods 149: 50-56.
38. Lee X, Yang Z, Shao Z, Rosenberg SS, Levesque M, et al. (2007) NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination. J Neurosci 27: 220-225.
39. Morello N, Bianchi FT, Marmiroli P, Tonoli E, Rodriguez Menendez V, et al. (2011) A role for hemopexin in oligodendrocyte differentiation and myelin formation. PLOS One 6: e20173.
40. Jones J, Estirado A, Redondo C, Bueno C, Martínez S (2012) Human adipose stem cell-conditioned medium increases survival of Friedreich's ataxia cells submitted to oxidative stress. Stem Cells Dev 21: 2817-2826.
41. Aarum J, Sandberg K, Haeberlein SL, Persson MA (2003) Migration and differentiation of neural precursor cells can be directed by microglia. Proc Natl Acad Sci USA 100: 15983-15988.
42. Vernerey J, Macchi M, Magalon K, Cayre M, Durbec P (2013) Ciliary neurotrophic factor controls progenitor migration during remyelination in the adult rodent brain. J Neuroscience 33: 3240-3250.
43. Baumann N, Pham-Dinh D (2001). Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiological Reviews 81: 871-927.
44. Kipp M, Clarner T, Dang J, Copray S, Beyer C (2009) The cuprizone animal model: new insights into an old story. Acta Neuropathol 118: 723-736.
45. Armstrong RC, Le TQ, Flint NC, Vana AC, Zhou YX (2006) Endogenous cell repair of chronic demyelination. J Neuropathol Exp Neurol 65: 245-256.
46. Bansal R, Kumar M, Murray K, Morrison RS, Pfeiffer SE (1996) Regulation of FGF receptors in the oligodendrocyte lineage. Mol and Cell Neurosci 7: 263-275.
47. McKinnon RD, Matsui T, Dubois-Dalcq M, Aaronson SA (1990) FGF modulates the PDGF-driven pathway of oligodendrocyte development. Neuron 5: 603-614.
48. Bogler O, Wren D, Barnett SC, Land H, Noble M (1990) Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells. Proc Natl Acad Sci USA 87: 6368-6372.
49. Grinspan JB, Stern JL, Franceschini B, Pleasure D (1993) Trophic effects of basic fibroblast growth factor (bFGF) on differentiated oligodendroglia: a mechanism for regeneration of the oligodendroglial lineage. J Neurosci Res 36: 672-680.
50. Fressinaud C, Vallat JM, Labourdette G (1995) Basic fibroblast growth factor down-regulates myelin basic protein gene expression and alters myelin compaction of mature oligodendrocytes in vitro. J Neurosci Res 40: 285-293.
51. Fortin D, Rom E, Sun H, Yayon A, Bansal R (2005) Distinct fibroblast growth factor (FGF)/FGF receptor signaling pairs initiate diverse cellular responses in the oligodendrocyte lineage. J Neurosci 25: 7470-7479.
52. Chari DM (2007) Remyelination in multiple sclerosis. Int Rev Neurobiol 79: 589-620.
53. Sim FJ, Zhao C, Penderis J, Franklin RJ (2002) The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 22: 2451-2459.