The therapeutic efficacy of α-pinene in an experimental mouse model of allergic rhinitis

International Immunopharmacology

Volumn 23, Issue 1, 2014, Pages 273-282

  Nam, Sun Young ^a   Chung, Cha Kwon ^b   Seo, Jun Ho ^c   Rah, So Young ^c   Kim, Hyung Min ^a   Jeong, Hyun Ja ^d  

^a Kyung Hee University   (South Korea)

^b Hallym University   (South Korea)

^c Chonbuk National University   (South Korea)

^d Hoseo University   (South Korea)

Author keywords

Allergic rhinitis; Inflammation; Mast cells; Pinene

Indexed keywords

ANTIALLERGIC AGENT; CXCL3 CHEMOKINE; I KAPPA B; IMMUNOGLOBULIN E; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 4; OVALBUMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING PROTEIN; PINENE; TUMOR NECROSIS FACTOR ALPHA; ALPHA-PINENE; CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; I KAPPA B KINASE; ICAM1 PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE 2; RIPK2 PROTEIN, HUMAN; TERPENE;

ALLERGIC RHINITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; EOSINOPHIL; EXPERIMENTAL MOUSE; FEMALE; HUMAN; HUMAN CELL; MAST CELL; MOUSE; NONHUMAN; NOSE MUCOSA; ORGAN WEIGHT; PROTEIN PHOSPHORYLATION; SENSITIZATION; SPLEEN; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CELL MOTION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; RHINITIS, ALLERGIC; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-ALLERGIC AGENTS; CASPASE 1; CELL LINE; CELL MOVEMENT; CHEMOKINE CXCL2; DISEASE MODELS, ANIMAL; EOSINOPHILS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; IMMUNOGLOBULIN E; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-4; MAST CELLS; MICE, INBRED BALB C; MONOTERPENES; NASAL MUCOSA; NF-KAPPA B; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; RHINITIS, ALLERGIC; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907897623     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.09.010     Document Type: Article

References (41)

1. J. Bousquet, P. Van Cauwenberge, N. Khaltaev, ARIA Workshop Group, and World Health Organization Allergic rhinitis and its impact on asthma J Allergy Clin Immunol 108 5 Suppl. 2001 S147 S334
2. A.G. Togias Systemic immunologic and inflammatory aspects of allergic rhinitis J Allergy Clin Immunol 106 5 2000 S247 S250
3. D. Strachan, B. Sibbald, S. Weiland, N. Aït-Khaled, G. Anabwani, and H.R. Anderson Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC) Pediatr Allergy Immunol 8 1997 161 176
4. K.J. Turner, G.A. Stewart, A.J. Woolcock, W. Green, and M.P. Alpers Relationship between mite densities and the prevalence of asthma: comparative studies in two populations in the Eastern Highlands of Papua New Guinea Clin Allergy 18 1988 331 340
5. E. Von Mutius, F.D. Martinez, C. Fritzsch, T. Nicolai, G. Roell, and H.H. Thiemann Prevalence of asthma and atopy in two areas of West and East Germany Am J Respir Crit Care Med 149 1994 358 364
6. S. Walker, S. Khan-Wasti, M. Fletcher, P. Cullinan, J. Harris, and A. Sheikh Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: case-control study J Allergy Clin Immunol 120 2007 381 387
7. M. Okuda The pathophysiology of allergic rhinitis ACI News 1 1992 167 176
8. M. Benson, M. Ander, and L.O. Cardell Cytokines and cytokine receptors in allergic rhinitis: how do they relate to the Th2 hypothesis in allergy? Clin Exp Allergy 31 2001 361 367
9. J. Bousquet, R. Lockey, and H.J. Malling Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper J Allergy Clin Immunol 102 1998 58 62
10. J.Y. Zhou, F.D. Tang, G.G. Mao, and R.L. Bian Effect of alpha-pinene on nuclear translocation of NF-kappa B in THP-1 cells Acta Pharmacol Sin 25 2004 480 484
11. J.L. Simonsen 2nd ed. The terpenes vol. 2 1957 Cambridge University Press Cambridge 105 191
12. F. Bakkali, S. Averbeck, D. Averbeck, and M. Idaomar Biological effects of essential oils - a review Food Chem Toxicol 46 2008 446 475
13. J.R. Lazutka, J. Mierauskien, G. Slap, and V. Dedonyt Genotoxicity of dill (Anethum graveolens L.), peppermint (Mentha piperita L.) and pine (Pinus sylvestris L.) essential oils in human lymphocytes and Drosophila melanogaster Food Chem Toxicol 39 2001 485 492
14. A.L. Matsuo, C.R. Figueiredo, D.C. Arruda, F.V. Pereira, J.A. Scutti, and M.H. Massaoka α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model Biochem Biophys Res Commun 29 2011 411 454
15. L. Nissen, A. Zatta, I. Stefanini, S. Grandi, B. Sgorbati, and B. Biavati Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.) Fitoterapia 81 2010 413 419
16. S. Martin, E. Padilla, M.A. Ocete, J. Galvez, J. Jimménez, and A. Zarzuelo Anti-inflammatory activity of the essential oil of Bupleurum fruticescens Planta Med 59 1993 533 536
17. G.S. Bae, K.C. Park, S.B. Choi, I.J. Jo, M.O. Choi, and S.H. Hong Protective effects of alpha-pinene in mice with cerulean-induced acute pancreatitis Life Sci 91 2012 866 871
18. A.T. Rufino, M. Ribeiro, F. Judas, L. Salgueiro, M.C. Lopes, and C. Cavaleiro Anti-inflammatory and chondroprotective activity of (+)-α-Pinene: structural and enantiomeric selectivity J Nat Prod 77 2014 264 269
19. H.A. Oh, H.M. Kim, and H.J. Jeong Distinct effects of imperatorin on allergic rhinitis: imperatorin inhibits caspase-1 activity in vivo and in vitro J Pharmacol Exp Ther 339 2011 72 81
20. H.J. Jeong, S.Y. Shin, H.A. Oh, M.H. Kim, J.S. Cho, and H.M. Kim IL-32 up-regulation is associated with inflammatory cytokine production in allergic rhinitis J Pathol 224 2011 553 563
21. K. Kobayashi, N. Inohara, L.D. Hernandez, J.E. Galán, G. Núñez, and C.A. Janeway RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems Nature 416 2002 194 199
22. N. Inohara, T. Koseki, J. Lin, L. del Peso, P.C. Lucas, and F.F. Chen An induced proximity model for NF-kappaB activation in the Nod1/RICK and RIP signaling pathways J Biol Chem 275 2000 27823 27831
23. K. Bloemen, S. Verstraelen, R. van Den Heuvel, H. Witters, I. Nelissen, and G. Schoeters The allergic cascade: review of the most important molecules in the asthmatic lung Immunol Lett 113 2007 6 18
24. J.A. Elias Airway remodeling in asthma. Unanswered questions Am J Respir Crit Care Med 161 2000 S168 S171
25. R. Pawankar, S. Mori, C. Ozu, and S. Kimura Overview on the pathomechanisms of allergic rhinitis Asia Pac Allergy 3 2011 157 167
26. Y. Isobe, T. Kato, and M. Arita Emerging roles of eosinophils and eosinophil-derived lipid mediators in the resolution of inflammation Front Immunol 3 2012 270
27. J. Bystrom, S.Y. Patel, K. Amin, and D. Bishop-Bailey Dissecting the role of eodinophil cationic protein in upper airway disease Curr Opin Allergy Clin Immunol 12 2012 18 23
28. R. Pawankar, K.H. Lee, M. Nonaka, and R. Takizawa Role of mast cells and basophils in chronic rhinosinusitis Clin Allergy Immunol 20 2007 93 101
29. W.B. Xu, E.B. Haddad, H. Tsukagoshi, I. Adcock, P.J. Barnes, and K.F. Chung Induction of macrophage inflammatory protein 2 gene expression by interleukin 1 beta in rat lung Thorax 50 1995 1136 1140
30. S.N. Mandhane, J.H. Shah, and R. Thennati Allergic rhinitis: an update on disease, present treatments and future prospects Int Immunopharmacol 11 2011 1646 1662
31. G. Nilsson, T. Blom, M. Kusche-Gullberg, L. Kjellén, J.H. Butterfield, and C. Sundstrom Phenotypic characterization of the human mast-cell line HMC-1 Scand J Immunol 39 1994 489 498
32. P. Valent, and P. Bettelheim Cell surface structures on human basophils and mast cells: biochemical and functional characterization Adv Immunol 52 1992 333 423
33. J. Lago, A. Alfonso, M.R. Vieytes, and L.M. Botana Ouabain-induced enhancement of rat mast cells response. Modulation by protein phosphorylation and intracellular pH Cell Signal 13 2011 515 524
34. Y. Baba, K. Nishida, Y. Fujii, T. Hirano, M. Hikida, and T. Kurosaki Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses Nat Immunol 9 2008 81 88
35. H.J. Jeong, H.S. Chung, B.R. Lee, S.J. Kim, S.J. Yoo, and S.H. Hong Expression of proinflammatory cytokines via HIF-1 alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells Biochem Biophys Res Commun 306 2003 805 811
36. K. Singh, R. Chaturvedi, D.P. Barry, L.A. Coburn, M. Asim, and N.D. Lewis The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis J Biol Chem 286 2011 3839 3850
37. Y. Yamamoto, and R.B. Gaynor Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer J Clin Invest 107 2001 135 142
38. N. Inohara, T. Koseki, J. Lin, L. del Peso, P.C. Lucas, and F.F. Chen An induced proximity model for NF-kappaB activation in the Nod1/RICK and RIP signaling pathways J Biol Chem 275 2000 27823 27831
39. H.J. Jeong, N.R. Han, K.Y. Kim, I.S. Choi, and H.M. Kim Gomisin A decreases the LPS-induced expression of iNOS and COX-2 and activation of RIP2/NF-κB in mouse peritoneal macrophages Immunopharmacol Immunotoxicol 36 2014 195 201
40. X. Jiang, and Z.J. Chen The role of ubiquitylation in immune defence and pathogen evasion Nat Rev Immunol 12 2012 35 48
41. Y.H. Song, S.Y. Nam, Y.J. Choi, J.H. Kim, Y.S. Kim, and H.J. Jeong Socioeconomic impact traditional Korean medicine, Pyeongwee-San (KMP6) as an antiallergic inflammatory drug TANG 2 2012 e29