3,5,4′-Trihydroxy-6,7,3′-trimethoxyflavone protects astrocytes against oxidative stress via interference with cell signaling and by reducing the levels of intracellular reactive oxygen species

Neurochemistry International

Volumn 78, Issue , 2014, Pages 67-75

  Elmann, Anat ^a   Telerman, Alona ^a   Mordechay, Sharon ^a   Erlank, Hilla ^a   Rindner, Miriam ^a   Ofir, Rivka ^b   Kashman, Yoel ^c  

^a VOLCANI CENTER   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

3,5,4 trihydroxy 6,7,3 trimethoxyflavone; Achillea fragrantissima; Astrocytes; Flavonoids; Neurodegenerative diseases; Oxidative stress

Indexed keywords

3,5,4' TRIHYDROXY 6,7,3' TRIMETHOXYFLAVONE; ANTIOXIDANT; CYCLIC AMP; FLAVONE DERIVATIVE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; PLANT EXTRACT;

ACHILLEA; ACHILLEA FRAGRANTISSIMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; BIOLOGY; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; GLIA CELL; INTRACELLULAR SIGNALING; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PRIMARY CULTURE; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; DRUG EFFECTS; INTRACELLULAR FLUID; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ACHILLEA; ANIMALS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; FLAVONES; HYDROGEN PEROXIDE; INTRACELLULAR FLUID; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84907896837     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2014.09.003     Document Type: Article

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