Modeling and molecular dynamics simulations of the V33 variant of the integrin subunit β3: Structural comparison with the L33 (HPA-1a) and P33 (HPA-1b) variants

Biochimie

Volumn 105, Issue , 2014, Pages 84-90

  Jallu, Vincent ^a   Poulain, Pierre ^a,b,c,d,e   Fuchs, Patrick F J ^a,b,c,d,f   Kaplan, Cecile ^a   De Brevern, Alexandre G ^a,b,c,d  

^a INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Laboratoire d'Excellence   (France)

^e Ets Poulain   (Congo)

^f INSTITUT JACQUES MONOD   (France)

Author keywords

HPA 1; Integrin alphaIIb beta3; Molecular dynamics simulation; Platelet; V33 beta3 antigenicity

Indexed keywords

ALLOANTIGEN; BETA3 INTEGRIN; HUMAN PLATELET ALLOANTIGEN 1A; HUMAN PLATELET ALLOANTIGEN 1B; PROLINE; THROMBOCYTE ANTIGEN; UNCLASSIFIED DRUG; VALINE; 1A ALLOANTIGEN, HUMAN; ALLOANTIBODY; EPITOPE; FIBRINOGEN RECEPTOR; HUMAN PLATELET ANTIGEN 1B;

ARTICLE; HYDROGEN BOND; MOLECULAR DYNAMICS; PHYSICAL CHEMISTRY; PROTEIN CONFORMATION; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; THROMBOCYTE; THROMBOCYTOPENIA;

ANTIGENS, HUMAN PLATELET; BLOOD PLATELETS; EPITOPES; HUMANS; ISOANTIBODIES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBOCYTOPENIA;

EID: 84907857182     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.06.017     Document Type: Article

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