Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Journal of Virological Methods

Volumn 209, Issue , 2014, Pages 116-120

  Morales Nebreda, Luisa ^a   Chi, Monica ^a   Lecuona, Emilia ^a   Chandel, Navdeep S ^a   Dada, Laura A ^a   Ridge, Karen ^a   Soberanes, Saul ^a   Nigdelioglu, Recep ^a   Sznajder, Jacob I ^a   Mutlu, Gökhan M ^a   Budinger, G R Scott ^a   Radigan, Kathryn A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Influenza A infection; Inoculation; Intranasal; Intratracheal; Lung injury; Mice

Indexed keywords

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; HISTOPATHOLOGY; INFLUENZA VIRUS A H1N1; INOCULATION; INTERMETHOD COMPARISON; MALE; MOUSE; NONHUMAN; VIRUS LOAD; VIRUS REPLICATION; ANIMAL; BODY WEIGHT; C57BL MOUSE; COMPARATIVE STUDY; COMPLICATION; CYTOCHEMISTRY; GROWTH, DEVELOPMENT AND AGING; HUMAN; INFLUENZA A VIRUS; LUNG; NOSE CAVITY; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; PHYSIOLOGY; TRACHEA; VIROLOGY;

ACUTE LUNG INJURY; ANIMALS; BODY WEIGHT; BRAIN; DISEASE MODELS, ANIMAL; HISTOCYTOCHEMISTRY; HUMANS; INFLUENZA A VIRUS; LUNG; MALE; MICE, INBRED C57BL; NASAL CAVITY; ORTHOMYXOVIRIDAE INFECTIONS; TRACHEA; VIRAL LOAD;

EID: 84907808860     PISSN: 01660934     EISSN: 18790984     Source Type: Journal    
DOI: 10.1016/j.jviromet.2014.09.004     Document Type: Article

References (13)

1. Abdul-Careem M.F., Firoz Mian M., Gillgrass A.E., Chenoweth M.J., Barra N.G., Chan T., Al-Garawi A.A., Chew M.V., Yue G., van Roojen N., Xing Z., Ashkar A.A. FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice. Antivir. Res. 2011, 92:346-355.
2. Blazejewska P., Koscinski L., Viegas N., Anhlan D., Ludwig S., Schughart K. Pathogenicity of different PR8 influenza A virus variants in mice is determined by both viral and host factors. Virology 2011, 412:36-45.
3. Hashimoto Y., Moki T., Takizawa T., Shiratsuchi A., Nakanishi Y. Evidence for phagocytosis of influenza virus-infected, apoptotic cells by neutrophils and macrophages in mice. J. Immunol. 2007, 178:2448-2457.
4. Jing X., Ma C., Ohigashi Y., Oliveira F.A., Jardetzky T.S., Pinto L.H., Lamb R.A. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:10967-10972.
5. Matrosovich M., Matrosovich T., Garten W., Klenk H.D. New low-viscosity overlay medium for viral plaque assays. Virol. J. 2006, 3:63.
6. Mutlu G.M., Green D., Bellmeyer A., Baker C.M., Burgess Z., Rajamannan N., Christman J.W., Foiles N., Kamp D.W., Ghio A.J., Chandel N.S., Dean D.A., Sznajder J.I., Budinger G.R. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J. Clin. Invest. 2007, 117:2952-2961.
7. Nhu Q.M., Shirey K., Teijaro J.R., Farber D.L., Netzel-Arnett S., Antalis T.M., Fasano A., Vogel S.N. Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo. Mucosal Immunol. 2010, 3:29-39.
8. Radigan K.A., Urich D., Misharin A.V., Chiarella S.E., Soberanes S., Gonzalez A., Perlman H., Wunderink R.G., Budinger G.R., Mutlu G.M. The effect of rosuvastatin in a murine model of influenza a infection. PLoS ONE 2012, 7:e35788.
9. Shirey K.A., Lai W.D., Scott A.J., Lipsky M., Mistry P., Pletneva L.M., Karp C.L., McAlees J., Gioannini T.L., Weiss J., Chen W.H., Ernst R.K., Rossignol D.P., Gusovsky F., Blanco J.C.G., Vogel S.N. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature 2013, 497:498-502.
10. Shrestha S.S., Swerdlow D.L., Borse R.H., Prabhu V.S., Finelli L., Atkins C.Y., Owusu-Edusei K., Bell B., Mead P.S., Biggerstaff M., Brammer L., Davidson H., Jernigan D., Jhung M.A., Kamimoto L.A., Merlin T.L., Nowell M., Redd S.C., Reed C., Schuchat A., Meltzer M.I. Estimating the burden of 2009 pandemic influenza A (H1N1) in the United States (April 2009-April 2010). Clin. Infect. Dis. 2011, 52:S75-S82.
11. Shrestha S.S., Swerdlow D.L., Borse R.H., Prabhu V.S., Finelli L., Atkins C.Y., Owusu-Edusei K., Bell B., Mead P.S., Biggerstaff M., Brammer L., Davidson H., Jernigan D., Jhung M.A., Kamimoto L.A., Merlin T.L., Nowell M., Redd S.C., Reed C., Schuchat A., Meltzer M.I. Estimating the burden of 2009 pandemic influenza A (H1N1) in the United States (April 2009-April 2010). Clin. Infect. Dis. 2011, 52(Suppl. 1):S75-S82.
12. Van Reeth K. Cytokines in the pathogenesis of influenza. Vet. Microbiol. 2000, 74:109-116.
13. Witt N.J., Zochodne D.W., Bolton C.F., Grand'Maison F., Wells G., Young G.B., Sibbald W.J. Peripheral nerve function in sepsis and multiple organ failure. Chest 1991, 99:176-184.