Pathogenicity of different PR8 influenza A virus variants in mice is determined by both viral and host factors

Virology

Volumn 412, Issue 1, 2011, Pages 36-45

  Blazejewska, Paulina ^a   Koscinski, Lukasz ^b   Viegas, Nuno ^a   Anhlan, Darisuren ^c   Ludwig, Stephan ^c   Schughart, Klaus ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

H1N1; Host response; Inbred strains; Influenza; Mouse genetics; Pathogenesis; PR8

Indexed keywords

AMINO ACID; HEMAGGLUTININ; PROTEINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DBA 2 MOUSE; ENZYME MODIFICATION; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; LETHALITY; LEUKOCYTE; LUNG ALVEOLUS; LYMPHOCYTIC INFILTRATION; MORTALITY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; LEUKOCYTES; LUNG; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MODELS, MOLECULAR; ORTHOMYXOVIRIDAE INFECTIONS; PROTEIN STRUCTURE, TERTIARY; SURVIVAL ANALYSIS; VIRAL LOAD; VIRULENCE; VIRULENCE FACTORS;

INFLUENZA A VIRUS; MUS;

EID: 79952537278     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.12.047     Document Type: Article

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