메뉴 건너뛰기




Volumn 1841, Issue 11, 2014, Pages 1639-1646

Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation

Author keywords

Creatine; Fatty acid oxidation; Hepatocytes; Non alcoholic fatty liver disease; PPAR

Indexed keywords

CREATINE; CREATININE; GUANIDINOACETIC ACID; GUANIDINOPROPIONIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; METHYLGUANIDINE; OLEIC ACID; PARAOXON; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

EID: 84907782649     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.09.001     Document Type: Article
Times cited : (36)

References (38)
  • 1
    • 79251524594 scopus 로고    scopus 로고
    • Systematic review: The diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
    • J.K. Dowman, J.W. Tomlinson, and P.N. Newsome Systematic review: the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis Aliment. Pharmacol. Ther. 33 2011 525 540
    • (2011) Aliment. Pharmacol. Ther. , vol.33 , pp. 525-540
    • Dowman, J.K.1    Tomlinson, J.W.2    Newsome, P.N.3
  • 3
    • 36348969601 scopus 로고    scopus 로고
    • Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology
    • D.E. Vance, Z. Li, and R.L. Jacobs Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology J. Biol. Chem. 282 2007 33237 33241
    • (2007) J. Biol. Chem. , vol.282 , pp. 33237-33241
    • Vance, D.E.1    Li, Z.2    Jacobs, R.L.3
  • 4
    • 84873199254 scopus 로고    scopus 로고
    • Physiological roles of phosphatidylethanolamine N-methyltransferase
    • D.E. Vance Physiological roles of phosphatidylethanolamine N-methyltransferase Biochim. Biophys. Acta 1831 2013 626 632
    • (2013) Biochim. Biophys. Acta , vol.1831 , pp. 626-632
    • Vance, D.E.1
  • 5
    • 84867706295 scopus 로고    scopus 로고
    • S-adenosylmethionine in liver health, injury, and cancer
    • S.C. Lu, and J.M. Mato S-adenosylmethionine in liver health, injury, and cancer Physiol. Rev. 92 2012 1515 1542
    • (2012) Physiol. Rev. , vol.92 , pp. 1515-1542
    • Lu, S.C.1    Mato, J.M.2
  • 6
    • 0037960128 scopus 로고    scopus 로고
    • Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice
    • C. Ji, and N. Kaplowitz Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice Gastroenterology 124 2003 1488 1499
    • (2003) Gastroenterology , vol.124 , pp. 1488-1499
    • Ji, C.1    Kaplowitz, N.2
  • 7
    • 35349024283 scopus 로고    scopus 로고
    • Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis
    • Z. Song, I. Deaciuc, Z. Zhou, M. Song, T. Chen, D. Hill, and C.J. McClain Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis Am. J. Physiol. Gastrointest. Liver Physiol. 293 2007 G894 G902
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293 , pp. 894-G902
    • Song, Z.1    Deaciuc, I.2    Zhou, Z.3    Song, M.4    Chen, T.5    Hill, D.6    McClain, C.J.7
  • 8
    • 58649089148 scopus 로고    scopus 로고
    • Impaired sulfur-amino acid metabolism and oxidative stress in nonalcoholic fatty liver are alleviated by betaine supplementation in rats
    • Y. Kwon do, Y.S. Jung, S.J. Kim, H.K. Park, J.H. Park, and Y.C. Kim Impaired sulfur-amino acid metabolism and oxidative stress in nonalcoholic fatty liver are alleviated by betaine supplementation in rats J. Nutr. 139 2009 63 68
    • (2009) J. Nutr. , vol.139 , pp. 63-68
    • Kwon Do, Y.1    Jung, Y.S.2    Kim, S.J.3    Park, H.K.4    Park, J.H.5    Kim, Y.C.6
  • 10
    • 0033935979 scopus 로고    scopus 로고
    • Creatine and creatinine metabolism
    • M. Wyss, and R. Kaddurah-Daouk Creatine and creatinine metabolism Physiol. Rev. 80 2000 1107 1213
    • (2000) Physiol. Rev. , vol.80 , pp. 1107-1213
    • Wyss, M.1    Kaddurah-Daouk, R.2
  • 11
    • 0028360971 scopus 로고
    • Cloning and sequencing of rat kidney L-arginine:glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine
    • P. Guthmiller, J.F. Van Pilsum, J.R. Boen, and D.M. McGuire Cloning and sequencing of rat kidney L-arginine:glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine J. Biol. Chem. 269 1994 17556 17560
    • (1994) J. Biol. Chem. , vol.269 , pp. 17556-17560
    • Guthmiller, P.1    Van Pilsum, J.F.2    Boen, J.R.3    McGuire, D.M.4
  • 14
    • 73949154491 scopus 로고    scopus 로고
    • Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes
    • K.W. Ko, B. Erickson, and R. Lehner Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes Biochim. Biophys. Acta 1791 2009 1133 1143
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 1133-1143
    • Ko, K.W.1    Erickson, B.2    Lehner, R.3
  • 15
    • 84895020019 scopus 로고    scopus 로고
    • A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins - Brief report
    • C. Butkinaree, L. Guo, B. Ramkhelawon, A. Wanschel, J.L. Brodsky, K.J. Moore, and E.A. Fisher A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins - brief report Arterioscler. Thromb. Vasc. Biol. 34 2014 251 254
    • (2014) Arterioscler. Thromb. Vasc. Biol. , vol.34 , pp. 251-254
    • Butkinaree, C.1    Guo, L.2    Ramkhelawon, B.3    Wanschel, A.4    Brodsky, J.L.5    Moore, K.J.6    Fisher, E.A.7
  • 16
    • 80051815847 scopus 로고    scopus 로고
    • Different fatty acids inhibit apoB100 secretion by different pathways: Unique roles for ER stress, ceramide, and autophagy
    • J.M. Caviglia, C. Gayet, T. Ota, A. Hernandez-Ono, D.M. Conlon, H. Jiang, E.A. Fisher, and H.N. Ginsberg Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy J. Lipid Res. 52 2011 1636 1651
    • (2011) J. Lipid Res. , vol.52 , pp. 1636-1651
    • Caviglia, J.M.1    Gayet, C.2    Ota, T.3    Hernandez-Ono, A.4    Conlon, D.M.5    Jiang, H.6    Fisher, E.A.7    Ginsberg, H.N.8
  • 17
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 226 1957 497 509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 18
    • 38349092277 scopus 로고    scopus 로고
    • Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein
    • R.L. Jacobs, S. Lingrell, Y. Zhao, G.A. Francis, and D.E. Vance Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein J. Biol. Chem. 283 2008 2147 2155
    • (2008) J. Biol. Chem. , vol.283 , pp. 2147-2155
    • Jacobs, R.L.1    Lingrell, S.2    Zhao, Y.3    Francis, G.A.4    Vance, D.E.5
  • 19
    • 0021736887 scopus 로고
    • Determination of plasma total lipid profiles by capillary gas-liquid chromatography
    • J.J. Myher, and A. Kuksis Determination of plasma total lipid profiles by capillary gas-liquid chromatography J. Biochem. Biophys. Methods 10 1984 13 23
    • (1984) J. Biochem. Biophys. Methods , vol.10 , pp. 13-23
    • Myher, J.J.1    Kuksis, A.2
  • 20
    • 33947504253 scopus 로고    scopus 로고
    • Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation
    • R.L. Jacobs, S. Lingrell, J.R. Dyck, and D.E. Vance Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation J. Biol. Chem. 282 2007 4516 4523
    • (2007) J. Biol. Chem. , vol.282 , pp. 4516-4523
    • Jacobs, R.L.1    Lingrell, S.2    Dyck, J.R.3    Vance, D.E.4
  • 21
    • 50049105823 scopus 로고    scopus 로고
    • The regulation of AMP-activated protein kinase by upstream kinases
    • D. Carling, M.J. Sanders, and A. Woods The regulation of AMP-activated protein kinase by upstream kinases Int. J. Obes. 32 Suppl. 4 2008 S55 S59
    • (2008) Int. J. Obes. , vol.32 , Issue.SUPPL. 4 , pp. 55-S59
    • Carling, D.1    Sanders, M.J.2    Woods, A.3
  • 22
    • 0025192341 scopus 로고
    • Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase
    • S.P. Davies, A.T. Sim, and D.G. Hardie Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase Eur. J. Biochem. 187 1990 183 190
    • (1990) Eur. J. Biochem. , vol.187 , pp. 183-190
    • Davies, S.P.1    Sim, A.T.2    Hardie, D.G.3
  • 23
    • 0035195248 scopus 로고    scopus 로고
    • Methylation demand and homocysteine metabolism: Effects of dietary provision of creatine and guanidinoacetate
    • L.M. Stead, K.P. Au, R.L. Jacobs, M.E. Brosnan, and J.T. Brosnan Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate Am. J. Physiol. Endocrinol. Metab. 281 2001 E1095 E1100
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.281 , pp. 1095-E1100
    • Stead, L.M.1    Au, K.P.2    Jacobs, R.L.3    Brosnan, M.E.4    Brosnan, J.T.5
  • 25
    • 84875671236 scopus 로고    scopus 로고
    • Inhibitors of fatty acid synthesis induce PPAR alpha-regulated fatty acid beta-oxidative genes: Synergistic roles of L-FABP and glucose
    • H. Huang, A.L. McIntosh, G.G. Martin, A.D. Petrescu, K.K. Landrock, D. Landrock, A.B. Kier, and F. Schroeder Inhibitors of fatty acid synthesis induce PPAR alpha-regulated fatty acid beta-oxidative genes: synergistic roles of L-FABP and glucose PPAR Res. 2013 2013 865604
    • (2013) PPAR Res. , vol.2013 , pp. 865604
    • Huang, H.1    McIntosh, A.L.2    Martin, G.G.3    Petrescu, A.D.4    Landrock, K.K.5    Landrock, D.6    Kier, A.B.7    Schroeder, F.8
  • 26
    • 33845922351 scopus 로고    scopus 로고
    • Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis
    • N.J. Spann, S. Kang, A.C. Li, A.Z. Chen, E.P. Newberry, N.O. Davidson, S.T. Hui, and R.A. Davis Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis J. Biol. Chem. 281 2006 33066 33077
    • (2006) J. Biol. Chem. , vol.281 , pp. 33066-33077
    • Spann, N.J.1    Kang, S.2    Li, A.C.3    Chen, A.Z.4    Newberry, E.P.5    Davidson, N.O.6    Hui, S.T.7    Davis, R.A.8
  • 27
    • 84859157338 scopus 로고    scopus 로고
    • The degradation of apolipoprotein B100: Multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways
    • E.A. Fisher The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways Biochim. Biophys. Acta 1821 2012 778 781
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 778-781
    • Fisher, E.A.1
  • 29
    • 84877895229 scopus 로고    scopus 로고
    • Differential regulation of the expressions of the PGC-1alpha splice variants, lipins, and PPARalpha in heart compared to liver
    • B.P. Kok, J.R. Dyck, T.E. Harris, and D.N. Brindley Differential regulation of the expressions of the PGC-1alpha splice variants, lipins, and PPARalpha in heart compared to liver J. Lipid Res. 54 2013 1662 1677
    • (2013) J. Lipid Res. , vol.54 , pp. 1662-1677
    • Kok, B.P.1    Dyck, J.R.2    Harris, T.E.3    Brindley, D.N.4
  • 30
    • 84877615840 scopus 로고    scopus 로고
    • Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
    • L.S. Csaki, J.R. Dwyer, L.G. Fong, P. Tontonoz, S.G. Young, and K. Reue Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling Prog. Lipid Res. 52 2013 305 316
    • (2013) Prog. Lipid Res. , vol.52 , pp. 305-316
    • Csaki, L.S.1    Dwyer, J.R.2    Fong, L.G.3    Tontonoz, P.4    Young, S.G.5    Reue, K.6
  • 32
    • 0027182769 scopus 로고
    • Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver
    • Z. Cui, J.E. Vance, M.H. Chen, D.R. Voelker, and D.E. Vance Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver J. Biol. Chem. 268 1993 16655 16663
    • (1993) J. Biol. Chem. , vol.268 , pp. 16655-16663
    • Cui, Z.1    Vance, J.E.2    Chen, M.H.3    Voelker, D.R.4    Vance, D.E.5
  • 33
    • 0033016641 scopus 로고    scopus 로고
    • Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise
    • C.L. Carlson, and W.W. Winder Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise J. Appl. Physiol. 86 1999 669 674
    • (1999) J. Appl. Physiol. , vol.86 , pp. 669-674
    • Carlson, C.L.1    Winder, W.W.2
  • 35
    • 0035156869 scopus 로고    scopus 로고
    • Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization
    • B. Op 't Eijnde, B. Urso, E.A. Richter, P.L. Greenhaff, and P. Hespel Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization Diabetes 50 2001 18 23
    • (2001) Diabetes , vol.50 , pp. 18-23
    • Op 'T Eijnde, B.1    Urso, B.2    Richter, E.A.3    Greenhaff, P.L.4    Hespel, P.5
  • 36
    • 0029951120 scopus 로고    scopus 로고
    • High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women
    • C.P. Earnest, A.L. Almada, and T.L. Mitchell High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women Clin. Sci. 91 1996 113 118
    • (1996) Clin. Sci. , vol.91 , pp. 113-118
    • Earnest, C.P.1    Almada, A.L.2    Mitchell, T.L.3
  • 37
    • 84856174572 scopus 로고    scopus 로고
    • Creatine supplementation decreases oxidative DNA damage and lipid peroxidation induced by a single bout of resistance exercise
    • R. Rahimi Creatine supplementation decreases oxidative DNA damage and lipid peroxidation induced by a single bout of resistance exercise J. Strength Cond. Res. 25 2011 3448 3455
    • (2011) J. Strength Cond. Res. , vol.25 , pp. 3448-3455
    • Rahimi, R.1
  • 38
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver disease
    • L.A. Adams, and P. Angulo Recent concepts in non-alcoholic fatty liver disease Diabet. Med. 22 2005 1129 1133
    • (2005) Diabet. Med. , vol.22 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.