Creatine supplementation decreases oxidative DNA damage and lipid peroxidation induced by a single bout of resistance exercise

Journal of Strength and Conditioning Research

Volumn 25, Issue 12, 2011, Pages 3448-3455

  Rahimi, Rahman ^a,b  

^a UNIVERSITY OF KURDISTAN   (Iran)

^b UNIVERSITY OF GUILAN   (Iran)

Author keywords

8 hydroxy 2 deoxyguanosine; Cr monohydrate; Malondialdehyde

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8-HYDROXY-2'-DEOXYGUANOSINE; CREATINE; DEOXYGUANOSINE; DRUG DERIVATIVE; MALONALDEHYDE;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; GENETICS; HUMAN; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; URINE;

ADOLESCENT; ADULT; CREATINE; DEOXYGUANOSINE; DIETARY SUPPLEMENTS; DNA DAMAGE; DOUBLE-BLIND METHOD; HUMANS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RANDOM ALLOCATION; RESISTANCE TRAINING; YOUNG ADULT;

EID: 84856174572     PISSN: 10648011     EISSN: None     Source Type: Journal    
DOI: 10.1519/JSC.0b013e3182162f2b     Document Type: Article

References (45)

1. Ahmun, RP, Tong, RJ, and Grimshaw, PN. The effects of acute creatine supplementation on multiple sprint cycling and running performance in rugby players. J Strength Cond Res 19: 92-97, 2005. (Pubitemid 40417260)
2. Arent, SM, Pellegrino, JK, Williams, CA, DiFabio, DA, and Greenwood, JC. Nutritional supplementation, performance, and oxidative stress in college soccer players. J Strength Cond Res 24: 1117-1124, 2010.
3. Basta, P, Skarpańska-Stejnborn, A, and Pilaczyńska- Szcześniak, L. Creatine supplementation and parameters of exercise-induced oxidative stress after a standard rowing test. Stud Phys Cult Tour 13: 17-23, 2006.
4. Bloomer, RJ, Falvo, MJ, Fry, AC, Schilling, BK, Smith, WA, and Moore, CA. Oxidative stress response in trained men following repeated squats or sprints. Med Sci Sports Exerc 38: 1436-1442, 2006. (Pubitemid 44215752)
5. Bloomer, RJ and Goldfarb, AH. Anaerobic exercise and oxidative stress: A review. Can J Appl Physiol 29: 245-263, 2004. (Pubitemid 38834582)
6. Bloomer, RJ, Goldfarb, AH, Wideman, L, Mckenzie, MJ, and Consitt, LA. Effects of acute aerobic and anaerobic exercise on blood markers of oxidative stress. J Strength Cond Res 19: 276-285, 2005. (Pubitemid 40807073)
7. Bompa, TO. Periodization Training for Sports. Champaign, IL: Human Kinetics, 1999.
8. Brenner, M, Walberg Rankin, MJ, and Sebolt, D. The effects of creatine supplementation during resistance training in women. J Strength Cond Res 14: 207-213, 2003.
9. Cheng, KC, Cahill, DS, Kasai, H, Nishimura, S, and Loeb, LA. 8-Hydroxy, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. J Biol Chem 267: 166-172, 1992.
10. Dixon, CB, Robertson, RJ, Goss, FL, Timmer, JM, Nagle, EF, and Evans, RW. The effect of acute resistance exercise on serum malondialdehyde in resistance-trained and untrained collegiate men. J Strength Cond Res 20: 693-698, 2006. (Pubitemid 44448662)
11. Eckerson, JM, Stout, JR, Moore, GA, Stone, NJ, Nishimura, K, and Tamura, K. Effect of two and five days of creatine loading on anaerobic working capacity in women. J Strength Cond Res 18: 168-172, 2004.
12. Esterbauer, H, Schaur, RJ, and Zollner, H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Rad Biol Med 11: 81-128, 1991. (Pubitemid 121003917)
13. Grune, T, Reinheckel, T, and Davies, KJA. Degradation of oxidized proteins in mammalian cells. FASEB J 11: 526-534, 1997. (Pubitemid 27274426)
14. Gutteridge, JM and Halliwell, B. Free radicals and antioxidants in the year: A historical look to the future. Ann NY Acad Sci 899: 136-147, 2000. (Pubitemid 30352782)
15. Halliwell, B. Free radicals and antioxidants: A personal view. Nutr Rev 52: 253-265, 1994. (Pubitemid 24308025)
16. Halliwell, B and Aruoma, OI. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett 281: 9-19, 1991.
17. Helbock, HJ, Beckman, KB, and Ames, BN. 8-Hydroxyguanosine as biomarker of oxidative DNA damage. Meth Enzymol 300: 156-165, 1999.
18. Ji, LL. Free radicals and antioxidants in exercise and sports. In: Exercise and Sport Science. W.E. Garrett and D.T. Kirkendall, eds. Philadelphia, PA: Lippincott Williams and Wilkins, 2000. pp. 299-317.
19. Kasai, H, Tanooka, H, and Nashimura, S. Formation of 8-hydroxyguanine residues in DNA by X-irradiation. Gann 75: 1037-1039, 1984. (Pubitemid 15160095)
20. Konig, D, Wagner, KH, Elmadfa, I, and Berg, A. Exercise and oxidative stress: Significance of antioxidants with reference to inflammatory, muscular, and systemic stress. Exerc Immunol Rev 7: 108-133, 2001. (Pubitemid 32911045)
21. Kraemer, WJ and Volek, JS. Creatine supplementation. Its role in human performance. Clin Sports Med 18: 651-666, 1999. (Pubitemid 29319162)
22. Kreider, RB, Melton, C, Rasmussen, CJ, Greenwood, M, Lancaster, S, Cantler, EC, and Almada, AL. Long-term creatine supplementation does not significantly affect clinical markers of health in athletes. Mol Cell Biochem 244: 95-104, 2003. (Pubitemid 36411059)
23. Lawler, JM, Barnes, WS, Wu, G, and Song, W. Direct antioxidant properties of creatine. Biochem Biophys Res Commun 290: 47-52, 2002. (Pubitemid 34694462)
24. Lefavi, RG, McMillan, JL, Kahn, PJ, Crosby, JF, Digioacchino, RF, and Streater, AJ. Effects of creatine monohydrate on collegiate baseball and basketball players. J Strength Cond Res 12: 275, 1998.
25. McBride, JM, Kraemer, WJ, Triplett McBride, T, and Sebastianelli, W. Effect of resistance exercise on free radical production. Med Sci Sports Exerc 30: 67-72, 1998. (Pubitemid 28071385)
26. Muth, CM, Glenz, Y, Klaus, M, Radermacher, P, Speit, G, and Leverve, X. Influence of an orally effective SOD on hyperbaric oxygen-related cell damage. Free Radical Res 38: 927-932, 2004. (Pubitemid 39341688)
27. Naclerio, FJ, Jiménez, A, Alvar, BA, and Peterson, MD. Assessing strength and power in resistance training. J Hum Sport Exerc 4: 100-113, 2009.
28. Nakajima, S, Kamohara, S, Nakano, M, and Ohno, M. Antioxidant supplementation decrease the amount of urinary 8-OHdG excretion induced by a single bout of exercise. Jpn J Phys Fitness Sports Med 55: S251-S256, 2006.
29. Radak, Z, Pucsok, J, Meeseki, S, Csont, T, and Ferdinandy, P. Muscle soreness-induced reduction in force generation is accompanied by increased nitric oxide content and DNA damage in human skeletal muscle. Free Radic Biol Med 26: 1059-1063, 1999. (Pubitemid 29198379)
30. Rahimi, R, Boroujerdi, SS, Ghaeeni, S, and Noori, SR. The effect of different rest intervals between sets on the training volume of male athletes. Facta Univ Phys Educ Sport 5: 37-46, 2007.
31. Rahimi, R, Qaderi, M, Faraji, H, and Boroujerdi, SS. Effects of very short rest periods on hormonal responses to resistance exercise in men. J Strength Cond Res 24: 1851-1859, 2010.
32. Ramel, A, Wagner, KH, and Elmadfa, I. Plasma antioxidants and lipid oxidation after submaximal resistance exercise in men. Eur J Nutr 43: 2-6, 2004. (Pubitemid 38233171)
33. Rawson, ES and Persky, AM. Mechanisms of muscular adaptations to creatine supplementation. Int Sport Med J 8: 43-53, 2007.
34. Reid, MB. Redox modulation of skeletal muscle contraction: What we know and what we don't. J Appl Physiol 90: 724-731, 2001. (Pubitemid 32118935)
35. Remmen, HV, Hamilton, ML, and Richardson, A. Oxidative damage to DNA and aging. Exerc Sport Sci 31: 149-153, 2003. (Pubitemid 36886029)
36. Santos, RVT, Bassit, RA, Caperuto, EC, and Costa Rosa, LFBP. The effect of creatine supplementation upon inflammatory and muscle soreness markers after a 30 km race. Life Sci 75: 1917-1924, 2004. (Pubitemid 39092556)
37. Sen, CK, Rankinen, T, Vaisanen, S, and Rauramaa, R. Oxidative stress after human exercise: Effect of N-acetylcysteine supplementation. J Appl Physiol 76: 2570-2577, 1994. (Pubitemid 24184780)
38. Sestili, P, Martinelli, C, Bravi, G, Piccoli, G, Curci, R, Battistelli, M, Falcieri, E, Agostini, D, Gioacchini, AM, and Stocchi, V. Creatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activity. Free Radic Biol Med 40: 837-849, 2006. (Pubitemid 43327318)
39. Shephard, RJ and Shek, PN. Associations between physical activity and susceptibility to cancer: Possible mechanisms. Sports Med 26: 293-315, 1998. (Pubitemid 28548379)
40. Shi, M, Wang, X, Yamanaka, T, Ogita, F, Nakatani, K, and Takeuchi, T. Effects of anaerobic exercise and aerobic exercise on biomarkers of oxidative stress. Environ Health Prev Med 12: 202-208, 2007. (Pubitemid 350106360)
41. Shibutani, S, Takeshita, M, and Grollman, AP. Insertion of specific bases during DNA synthesis past the oxidation damaged 8-oxodG. Nature 349: 431-434, 1991. (Pubitemid 21926107)
42. Surmen-Gur, E, Ozturk, E, Gur, H, Punduk, Z, and Tuncel, P. Effect of vitamin E supplementation on post-exercise plasma lipid peroxidation and blood antioxidant status in smokers: With special reference to haemoconcentration effect. Eur J Appl Physiol Occup Physiol 79: 472-478, 1999. (Pubitemid 29201699)
43. Takeuchi, T, Nakajima, M, and Morimoto, K. Establishment of a human system that generates O2 and induces 8-hydroxydeoxyguanosine, typical of oxidative DNA damage, by a tumour promoter. Cancer Res 54: 5837-5840, 1994.
44. Takeuchi, T, Nakajima, M, Ohta, Y, Mure, K, Takeshita, T, and Morimoto, K. Evaluation of 8-hydroxydeoxyguanosine, a typical oxidative DNA damage, in human leukocytes. Carcinogenesis 15: 1519-1523, 1994. (Pubitemid 24262134)
45. Vergnani, L, Hatrick, S, Ricci, F, Passaro, A, Manzoli, N, Zuliani, G, and Brokovych, V. Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production: Key role of L-arginine availability. Circulation 101: 1261-1266, 2000. (Pubitemid 30158613)