The monoamine oxidase-A inhibitor clorgyline promotes a mesenchymal-to-epithelial transition in the MDA-MB-231 breast cancer cell line

Cellular Signalling

Volumn 26, Issue 12, 2014, Pages 2621-2632

  Satram Maharaj, Tamara ^a   Nyarko, Jennifer N K ^b   Kuski, Kelly ^a   Fehr, Kelsey ^a   Pennington, Paul R ^a   Truitt, Luke ^b   Freywald, Andrew ^b   Lukong, Kiven Erique ^b   Anderson, Deborah H ^b   Mousseau, Darrell D ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Breast cancer; Depression; E cadherin; Mesenchymal to epithelial transition; Metastasis; Monoamine oxidase

Indexed keywords

BETA CATENIN; CELL PROTEIN; CLORGYLINE; ESTROGEN RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; PROTEIN SNAI1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; AMINE OXIDASE (FLAVIN CONTAINING); CADHERIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER PATIENT; CELL MIGRATION; CELL SPECIFICITY; CELL TRANSFORMATION; COMORBIDITY; COMPLEX FORMATION; CONTROLLED STUDY; DEPRESSION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MCF 7 CELL LINE; MDA MB 231 CELL LINE; MESENCHYMAL TO EPITHELIAL TRANSITION; METASTASIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR INVASION; BREAST NEOPLASMS; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; FEMALE; GENETICS; METABOLISM; TUMOR CELL LINE;

BETA CATENIN; BREAST NEOPLASMS; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CLORGYLINE; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MCF-7 CELLS; MONOAMINE OXIDASE; NEOPLASM INVASIVENESS; RNA, MESSENGER; VIMENTIN;

EID: 84907684714     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.08.005     Document Type: Article

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