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Volumn 28, Issue 10, 2014, Pages 1629-1639

Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANTIANDROGEN; BETA CATENIN; NUCLEAR MESENCHYMAL EPITHELIAL TRANSITION FACTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; ANDROGEN RECEPTOR; MET PROTEIN, HUMAN; SOX9 PROTEIN, HUMAN;

EID: 84907678055     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/me.2014-1078     Document Type: Article
Times cited : (37)

References (49)
  • 1
    • 0015370976 scopus 로고
    • Studies on prostatic cancer. I. The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C, Hodges CV. Studies on prostatic cancer. I. The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. CA Cancer J Clin. 1972;22(4):232–240.
    • (1972) CA Cancer J Clin , vol.22 , Issue.4 , pp. 232-240
    • Huggins, C.1    Hodges, C.V.2
  • 2
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak DP, Tangen CM, Hussain MH, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med. 2004;351(15):1513–1520.
    • (2004) N Engl J Med , vol.351 , Issue.15 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 3
    • 84866021276 scopus 로고    scopus 로고
    • Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells
    • Domingo-Domenech J, Vidal SJ, Rodriguez-Bravo V, et al. Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. Cancer Cell. 2012;22(3):373–388.
    • (2012) Cancer Cell , vol.22 , Issue.3 , pp. 373-388
    • Domingo-Domenech, J.1    Vidal, S.J.2    Rodriguez-Bravo, V.3
  • 4
    • 79952821476 scopus 로고    scopus 로고
    • A role for OCT4 in tumor initiation of drug-resistant prostate cancer cells
    • Linn DE, Yang X, Sun F, et al. A role for OCT4 in tumor initiation of drug-resistant prostate cancer cells. Genes Cancer. 2010;1(9): 908–916.
    • (2010) Genes Cancer , vol.1 , Issue.9 , pp. 908-916
    • Linn, D.E.1    Yang, X.2    Sun, F.3
  • 5
    • 84859416889 scopus 로고    scopus 로고
    • Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells
    • Mulholland DJ, Kobayashi N, Ruscetti M, et al. Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res. 2012;72(7):1878–1889.
    • (2012) Cancer Res , vol.72 , Issue.7 , pp. 1878-1889
    • Mulholland, D.J.1    Kobayashi, N.2    Ruscetti, M.3
  • 6
    • 79955975429 scopus 로고    scopus 로고
    • Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
    • Carver BS, Chapinski C, Wongvipat J, et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 2011;19(5):575–586.
    • (2011) Cancer Cell , vol.19 , Issue.5 , pp. 575-586
    • Carver, B.S.1    Chapinski, C.2    Wongvipat, J.3
  • 7
    • 84863306923 scopus 로고    scopus 로고
    • Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases
    • Linn DE, Yang X, Xie Y, et al. Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases. J Biol Chem. 2012;287(27): 22959–22968.
    • (2012) J Biol Chem , vol.287 , Issue.27 , pp. 22959-22968
    • Linn, D.E.1    Yang, X.2    Xie, Y.3
  • 8
    • 33749445413 scopus 로고    scopus 로고
    • Regulation of androgen receptor activity by tyrosine phosphorylation
    • Guo Z, Dai B, Jiang T, et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell. 2006;10(4): 309–319.
    • (2006) Cancer Cell , vol.10 , Issue.4 , pp. 309-319
    • Guo, Z.1    Dai, B.2    Jiang, T.3
  • 9
    • 84875530398 scopus 로고    scopus 로고
    • ARF represses androgen receptor transactivation in prostate cancer
    • Lu W, Xie Y, Ma Y, Matusik RJ, Chen Z. ARF represses androgen receptor transactivation in prostate cancer. Mol Endocrinol. 2013; 27(4):635–648.
    • (2013) Mol Endocrinol , vol.27 , Issue.4 , pp. 635-648
    • Lu, W.1    Xie, Y.2    Ma, Y.3    Matusik, R.J.4    Chen, Z.5
  • 10
    • 80054761058 scopus 로고    scopus 로고
    • Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
    • Cai C, He HH, Chen S, et al. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell. 2011;20(4):457–471.
    • (2011) Cancer Cell , vol.20 , Issue.4 , pp. 457-471
    • Cai, C.1    He, H.H.2    Chen, S.3
  • 12
    • 33847057016 scopus 로고    scopus 로고
    • The androgen receptor negatively regulates the expression of c-Met: Implications for a novel mechanism of prostate cancer progression
    • Verras M, Lee J, Xue H, Li TH, Wang Y, Sun Z. The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression. Cancer Res. 2007;67(3):967–975.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 967-975
    • Verras, M.1    Lee, J.2    Xue, H.3    Li, T.H.4    Wang, Y.5    Sun, Z.6
  • 13
    • 84873365046 scopus 로고    scopus 로고
    • β4 Integrin signaling induces expansion of prostate tumor progenitors
    • Yoshioka T, Otero J, Chen Y, et al. b4 Integrin signaling induces expansion of prostate tumor progenitors. J Clin Invest. 2013; 123(2):682–699.
    • (2013) J Clin Invest , vol.123 , Issue.2 , pp. 682-699
    • Yoshioka, T.1    Otero, J.2    Chen, Y.3
  • 14
    • 84864285794 scopus 로고    scopus 로고
    • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    • Straussman R, Morikawa T, Shee K, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature. 2012;487(7408):500–504.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 500-504
    • Straussman, R.1    Morikawa, T.2    Shee, K.3
  • 15
    • 33748076105 scopus 로고    scopus 로고
    • Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density
    • Pozner-Moulis S, Pappas DJ, Rimm DL. Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density. Cancer Res. 2006;66(16):7976–7982.
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 7976-7982
    • Pozner-Moulis, S.1    Pappas, D.J.2    Rimm, D.L.3
  • 16
    • 42949163670 scopus 로고    scopus 로고
    • c-Met must translocate to the nucleus to initiate calcium signals
    • Gomes DA, Rodrigues MA, Leite MF, et al. c-Met must translocate to the nucleus to initiate calcium signals. J Biol Chem. 2008;283(7): 4344–4351.
    • (2008) J Biol Chem , vol.283 , Issue.7 , pp. 4344-4351
    • Gomes, D.A.1    Rodrigues, M.A.2    Leite, M.F.3
  • 17
    • 0035074356 scopus 로고    scopus 로고
    • Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase
    • Nath D, Williamson NJ, Jarvis R, Murphy G. Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase. J Cell Sci. 2001;114(pt 6):1213–1220.
    • (2001) J Cell Sci , vol.114 , pp. 1213-1220
    • Nath, D.1    Williamson, N.J.2    Jarvis, R.3    Murphy, G.4
  • 18
    • 34547749466 scopus 로고    scopus 로고
    • c-Met ectodomain shedding rate correlates with malignant potential
    • Athauda G, Giubellino A, Coleman JA, et al. c-Met ectodomain shedding rate correlates with malignant potential. Clin Cancer Res. 2006;12(14 pt 1):4154–4162.
    • (2006) Clin Cancer Res , vol.12-14 , pp. 4154-4162
    • Athauda, G.1    Giubellino, A.2    Coleman, J.A.3
  • 19
    • 84857817163 scopus 로고    scopus 로고
    • Slug and Sox9 cooperatively determine the mammary stem cell state
    • Guo W, Keckesova Z, Donaher JL, et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012;148(5): 1015–1028.
    • (2012) Cell , vol.148 , Issue.5 , pp. 1015-1028
    • Guo, W.1    Keckesova, Z.2    Donaher, J.L.3
  • 20
    • 33846910410 scopus 로고    scopus 로고
    • SOX9 is required for maintenance of the pancreatic progenitor cell pool
    • Seymour PA, Freude KK, Tran MN, et al. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci USA. 2007;104(6):1865–1870.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.6 , pp. 1865-1870
    • Seymour, P.A.1    Freude, K.K.2    Tran, M.N.3
  • 21
    • 84874598190 scopus 로고    scopus 로고
    • ERG induces androgen receptormediated regulation of SOX9 in prostate cancer
    • Cai C, Wang H, He HH, et al. ERG induces androgen receptormediated regulation of SOX9 in prostate cancer. J Clin Invest. 2013;123(3):1109–1122.
    • (2013) J Clin Invest , vol.123 , Issue.3 , pp. 1109-1122
    • Cai, C.1    Wang, H.2    He, H.H.3
  • 22
    • 33846673020 scopus 로고    scopus 로고
    • SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells
    • Wang H, McKnight NC, Zhang T, Lu ML, Balk SP, Yuan X. SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res. 2007; 67(2):528–536.
    • (2007) Cancer Res , vol.67 , Issue.2 , pp. 528-536
    • Wang, H.1    McKnight, N.C.2    Zhang, T.3    Lu, M.L.4    Balk, S.P.5    Yuan, X.6
  • 23
    • 0347087570 scopus 로고    scopus 로고
    • βCatenin signaling in prostate cancer: An early perspective
    • Chesire DR, Isaacs WB. b-Catenin signaling in prostate cancer: an early perspective. Endocr Relat Cancer. 2003;10(4):537–560.
    • (2003) Endocr Relat Cancer , vol.10 , Issue.4 , pp. 537-560
    • Chesire, D.R.1    Isaacs, W.B.2
  • 24
    • 84880769150 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling triggers neuron reprogramming and regeneration in the mouse retina
    • Sanges D, Romo N, Simonte G, et al. Wnt/b-catenin signaling triggers neuron reprogramming and regeneration in the mouse retina. Cell Rep. 2013;4(2):271–286.
    • (2013) Cell Rep , vol.4 , Issue.2 , pp. 271-286
    • Sanges, D.1    Romo, N.2    Simonte, G.3
  • 25
    • 76249098305 scopus 로고    scopus 로고
    • SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation
    • Thomsen MK, Ambroisine L, Wynn S, et al. SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res. 2010;70(3):979–987.
    • (2010) Cancer Res , vol.70 , Issue.3 , pp. 979-987
    • Thomsen, M.K.1    Ambroisine, L.2    Wynn, S.3
  • 26
    • 79958764107 scopus 로고    scopus 로고
    • Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
    • Mulholland DJ, Tran LM, Li Y, et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 2011;19(6):792–804.
    • (2011) Cancer Cell , vol.19 , Issue.6 , pp. 792-804
    • Mulholland, D.J.1    Tran, L.M.2    Li, Y.3
  • 27
    • 84879671701 scopus 로고    scopus 로고
    • A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
    • Lunardi A, Ala U, Epping MT, et al. A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nat Genet. 2013;45(7):747–755.
    • (2013) Nat Genet , vol.45 , Issue.7 , pp. 747-755
    • Lunardi, A.1    Ala, U.2    Epping, M.T.3
  • 28
    • 77954888748 scopus 로고    scopus 로고
    • Pim-1 kinase protects P-glycoprotein from degradation and enables its glycosylation and cell surface expression
    • Xie Y, Burcu M, Linn DE, Qiu Y, Baer MR. Pim-1 kinase protects P-glycoprotein from degradation and enables its glycosylation and cell surface expression. Mol Pharmacol. 2010;78(2):310–318.
    • (2010) Mol Pharmacol , vol.78 , Issue.2 , pp. 310-318
    • Xie, Y.1    Burcu, M.2    Linn, D.E.3    Qiu, Y.4    Baer, M.R.5
  • 29
    • 84908508684 scopus 로고    scopus 로고
    • Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis [published online May 21, 2014]
    • Xie Y, Liu S, Lu W, et al. Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis [published online May 21, 2014]. Mol Oncol. doi: 10.1016/j.molonc.2014.05.006.
    • Mol Oncol. , vol.5 , pp. 006
    • Xie, Y.1    Liu, S.2    Lu, W.3
  • 30
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • Chen Z, Trotman LC, Shaffer D, et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature. 2005;436(7051):725–730.
    • (2005) Nature , vol.436 , Issue.7051 , pp. 725-730
    • Chen, Z.1    Trotman, L.C.2    Shaffer, D.3
  • 31
    • 70350013557 scopus 로고    scopus 로고
    • Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes
    • Choudhary C, Olsen JV, Brandts C, et al. Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell. 2009;36(2):326–339.
    • (2009) Mol Cell , vol.36 , Issue.2 , pp. 326-339
    • Choudhary, C.1    Olsen, J.V.2    Brandts, C.3
  • 32
    • 79955046668 scopus 로고    scopus 로고
    • An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ wingless signaling pathway
    • Gonsalves FC, Klein K, Carson BB, et al. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ wingless signaling pathway. Proc Natl Acad Sci USA. 2011; 108(15):5954–5963.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.15 , pp. 5954-5963
    • Gonsalves, F.C.1    Klein, K.2    Carson, B.B.3
  • 33
    • 70350443240 scopus 로고    scopus 로고
    • Differential p53-independent outcomes of p19(Arf) loss in oncogenesis
    • ra44
    • Chen Z, Carracedo A, Lin HK, et al. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis. Sci Signal. 2009;2(84): ra44.
    • (2009) Sci Signal , vol.2 , Issue.84
    • Chen, Z.1    Carracedo, A.2    Lin, H.K.3
  • 34
    • 0034855942 scopus 로고    scopus 로고
    • Nuclear localization of EGF receptor and its potential new role as a transcription factor
    • Lin SY, Makino K, Xia W, et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol. 2001;3(9):802–808.
    • (2001) Nat Cell Biol , vol.3 , Issue.9 , pp. 802-808
    • Lin, S.Y.1    Makino, K.2    Xia, W.3
  • 35
    • 33751508862 scopus 로고    scopus 로고
    • Tyrosine phosphorylation controls PCNA function through protein stability
    • Wang SC, Nakajima Y, Yu YL, et al. Tyrosine phosphorylation controls PCNA function through protein stability. Nat Cell Biol. 2006;8(12):1359–1368.
    • (2006) Nat Cell Biol , vol.8 , Issue.12 , pp. 1359-1368
    • Wang, S.C.1    Nakajima, Y.2    Yu, Y.L.3
  • 36
    • 0034954160 scopus 로고    scopus 로고
    • The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair
    • Fan S, Ma YX, Gao M, et al. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair. Mol Cell Biol. 2001;21(15): 4968–4984.
    • (2001) Mol Cell Biol , vol.21 , Issue.15 , pp. 4968-4984
    • Fan, S.1    Ma, Y.X.2    Gao, M.3
  • 38
    • 84864589406 scopus 로고    scopus 로고
    • Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family
    • Wang YN, Hung MC. Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family. Cell Biosci. 2012;2(1):13.
    • (2012) Cell Biosci , vol.2 , Issue.1 , pp. 13
    • Wang, Y.N.1    Hung, M.C.2
  • 40
    • 0035824391 scopus 로고    scopus 로고
    • Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
    • Ni CY, Murphy MP, Golde TE, Carpenter G. Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science. 2001;294(5549):2179–2181.
    • (2001) Science , vol.294 , Issue.5549 , pp. 2179-2181
    • Ni, C.Y.1    Murphy, M.P.2    Golde, T.E.3    Carpenter, G.4
  • 41
    • 84876441841 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
    • Qi J, Tripathi M, Mishra R, et al. The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Cancer Cell. 2013; 23(3):332–346.
    • (2013) Cancer Cell , vol.23 , Issue.3 , pp. 332-346
    • Qi, J.1    Tripathi, M.2    Mishra, R.3
  • 42
    • 85027923138 scopus 로고    scopus 로고
    • NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
    • Jeter CR, Liu B, Liu X, et al. NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene. 2011;30(36):3833–3845.
    • (2011) Oncogene , vol.30 , Issue.36 , pp. 3833-3845
    • Jeter, C.R.1    Liu, B.2    Liu, X.3
  • 43
    • 79959971880 scopus 로고    scopus 로고
    • c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
    • Li Y, Li A, Glas M, et al. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc Natl Acad Sci USA. 2011;108(24):9951–9956.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.24 , pp. 9951-9956
    • Li, Y.1    Li, A.2    Glas, M.3
  • 44
    • 81055129938 scopus 로고    scopus 로고
    • Activation of c- MET induces a stem-like phenotype in human prostate cancer
    • van Leenders GJ, Sookhlall R, Teubel WJ, et al. Activation of c- MET induces a stem-like phenotype in human prostate cancer. PLoS One. 2011;6(11):e26753.
    • (2011) PLoS One , vol.6 , Issue.11
    • Van Leenders, G.J.1    Sookhlall, R.2    Teubel, W.J.3
  • 45
    • 84872689611 scopus 로고    scopus 로고
    • Prostate cancer stem cells: The case for model systems
    • Hynes PG, Kelly K. Prostate cancer stem cells: the case for model systems. J Carcinog. 2012;11:6.
    • (2012) J Carcinog , vol.11 , pp. 6
    • Hynes, P.G.1    Kelly, K.2
  • 46
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science. 2004;304(5670): 554.
    • (2004) Science , vol.304 , Issue.5670 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 47
    • 31144453233 scopus 로고    scopus 로고
    • BRAF mutation predicts sensitivity to MEK inhibition
    • Solit DB, Garraway LA, Pratilas CA, et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature. 2006;439(7074):358–362.
    • (2006) Nature , vol.439 , Issue.7074 , pp. 358-362
    • Solit, D.B.1    Garraway, L.A.2    Pratilas, C.A.3
  • 48
    • 79957982003 scopus 로고    scopus 로고
    • Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells
    • Huang WC, Chen YJ, Li LY, et al. Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J Biol Chem. 2011;286(23):20558–20568.
    • (2011) J Biol Chem , vol.286 , Issue.23 , pp. 20558-20568
    • Huang, W.C.1    Chen, Y.J.2    Li, L.Y.3
  • 49
    • 30044433786 scopus 로고    scopus 로고
    • The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs
    • Xie Y, Xu K, Dai B, et al. The 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs. Oncogene. 2006;25(1):70–78.
    • (2006) Oncogene , vol.25 , Issue.1 , pp. 70-78
    • Xie, Y.1    Xu, K.2    Dai, B.3


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