In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 22, 2014, Pages 5465-5476

  Carretero, Aitor ^a   León, Zacarías ^a   García Cañaveras, Juan Carlos ^a,b   Zaragoza, Ángela ^a   Gómez Lechón, María José ^a   Donato, María Teresa ^a,b   Lahoz, Agustín ^a  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Biomarker; Hepatocytes; NASH; Oxidative stress; Steatosis; UPLC MS MS

Indexed keywords

AMINO ACIDS; BIOMARKERS; DIAGNOSIS; LIPIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATIVE STRESS; PATIENT MONITORING; PHYSIOLOGY; PROTEINS;

FOOD AND DRUG ADMINISTRATION; HEPATOCYTES; NASH; NON-ALCOHOLIC STEATOHEPATITIS; STEATOSIS; STRAIGHTFORWARD STRATEGY; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

DAMAGE DETECTION;

RATTUS;

BIOLOGICAL MARKER; GLUTATHIONE TRANSFERASE; LIPID; MALONALDEHYDE; OXYGEN; PROTEIN;

ANIMAL; CHEMISTRY; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; HUMAN; LIVER; LIVER CELL; MALE; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS; PERFUSION; RAT; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA DAMAGE; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HOMEOSTASIS; HUMANS; LIPIDS; LIVER; MALE; MALONDIALDEHYDE; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS; OXYGEN; PERFUSION; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84907599286     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-7983-5     Document Type: Article

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