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Volumn 396, Issue 1-2, 2014, Pages 87-98

Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries

Author keywords

Calcium sensing receptors; Phenotypic modulation; Pulmonary arterial hypertension; Smooth muscle cells

Indexed keywords

CALCIUM SENSING RECEPTOR; CASR PROTEIN, HUMAN; CYCLINE; EXTRACELLULAR CALCIUM CATION-SENSING RECEPTOR, RAT; GELATINASE A; GELATINASE B; TIMP3 PROTEIN, HUMAN; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

EID: 84907591584     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2145-9     Document Type: Article
Times cited : (40)

References (42)
  • 1
    • 79960961583 scopus 로고    scopus 로고
    • Mechanisms of disease: Pulmonary arterial hypertension
    • 21691314 1:CAS:528:DC%2BC3MXptlymsb0%3D
    • Schermuly RT, Ghofrani HA, Wilkins MR, Grimminger F (2011) Mechanisms of disease: pulmonary arterial hypertension. Nat Rev Cardiol 8:443-455. doi: 10.1038/nrcardio.2011.87
    • (2011) Nat Rev Cardiol , vol.8 , pp. 443-455
    • Schermuly, R.T.1    Ghofrani, H.A.2    Wilkins, M.R.3    Grimminger, F.4
  • 2
    • 84893779314 scopus 로고    scopus 로고
    • Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice
    • 24089267 1:CAS:528:DC%2BC2cXitFaktb4%3D
    • Guo Q, Huang JA, Yamamura A, Yamamura H, Zimnicka AM, Fernandez R, Yuan JX (2014) Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice. Hypertens Res 37:116-124. doi: 10.1038/hr.2013.129
    • (2014) Hypertens Res , vol.37 , pp. 116-124
    • Guo, Q.1    Huang, J.A.2    Yamamura, A.3    Yamamura, H.4    Zimnicka, A.M.5    Fernandez, R.6    Yuan, J.X.7
  • 3
    • 77952234421 scopus 로고    scopus 로고
    • Basic science of pulmonary arterial hypertension for clinicians: New concepts and experimental therapies
    • 20458021 2869481
    • Archer SL, Weir EK, Wilkins MR (2010) Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation 121:2045-2066. doi: 10.1161/CIRCULATIONAHA.108.847707
    • (2010) Circulation , vol.121 , pp. 2045-2066
    • Archer, S.L.1    Weir, E.K.2    Wilkins, M.R.3
  • 4
    • 78249243379 scopus 로고    scopus 로고
    • Contribution of myocardin in the hypoxia-induced phenotypic switching of rat pulmonary arterial smooth muscle cells
    • 20621093 1:CAS:528:DC%2BC3cXhsVans7rL
    • Jie W, Guo J, Shen Z, Wang X, Zheng S, Wang G, Ao Q (2010) Contribution of myocardin in the hypoxia-induced phenotypic switching of rat pulmonary arterial smooth muscle cells. Exp Mol Pathol 89:301-306. doi: 10.1016/j.yexmp.2010.06.010
    • (2010) Exp Mol Pathol , vol.89 , pp. 301-306
    • Jie, W.1    Guo, J.2    Shen, Z.3    Wang, X.4    Zheng, S.5    Wang, G.6    Ao, Q.7
  • 5
    • 0028025190 scopus 로고
    • Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo
    • 7923613 1:STN:280:DyaK2M%2FgvVSnuw%3D%3D
    • Frid MG, Moiseeva EP, Stenmark KR (1994) Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo. Circ Res 75:669-681
    • (1994) Circ Res , vol.75 , pp. 669-681
    • Frid, M.G.1    Moiseeva, E.P.2    Stenmark, K.R.3
  • 6
    • 34447513281 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II-delta isoform regulation of vascular smooth muscle cell proliferation
    • 17267544 1:CAS:528:DC%2BD2sXmvF2msbs%3D
    • House SJ, Ginnan RG, Armstrong SE, Singer HA (2007) Calcium/calmodulin-dependent protein kinase II-delta isoform regulation of vascular smooth muscle cell proliferation. Am J Physiol Cell Physiol 292:C2276-C2287. doi: 10.1152/ajpcell.00606.2006
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. 2276-C2287
    • House, S.J.1    Ginnan, R.G.2    Armstrong, S.E.3    Singer, H.A.4
  • 7
    • 84855317520 scopus 로고    scopus 로고
    • STIM2 Contributes to enhanced store-operated ca entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
    • 21709766 1:CAS:528:DC%2BC3MXpsVantb0%3D 3121304
    • Song MY, Makino A, Yuan JX (2011) STIM2 Contributes to enhanced store-operated ca entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Pulm Circ 1:84-94. doi: 10.4103/2045-8932.78106
    • (2011) Pulm Circ , vol.1 , pp. 84-94
    • Song, M.Y.1    Makino, A.2    Yuan, J.X.3
  • 8
    • 77951224753 scopus 로고    scopus 로고
    • The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction
    • 20204731 1:CAS:528:DC%2BC3cXhsFyjtr3I
    • Fuchs B, Dietrich A, Gudermann T, Kalwa H, Grimminger F, Weissmann N (2010) The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction. Adv Exp Med Biol 661:187-200. doi: 10.1007/978-1-60761-500-2-12
    • (2010) Adv Exp Med Biol , vol.661 , pp. 187-200
    • Fuchs, B.1    Dietrich, A.2    Gudermann, T.3    Kalwa, H.4    Grimminger, F.5    Weissmann, N.6
  • 9
    • 4444352981 scopus 로고    scopus 로고
    • Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: A novel mechanism of hypoxic pulmonary hypertension
    • 15256480 1:CAS:528:DC%2BD2cXntVCrtLw%3D
    • Lin MJ, Leung GP, Zhang WM, Yang XR, Yip KP, Tse CM, Sham JS (2004) Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension. Circ Res 95:496-505. doi: 10.1161/01.RES.0000138952.16382.ad
    • (2004) Circ Res , vol.95 , pp. 496-505
    • Lin, M.J.1    Leung, G.P.2    Zhang, W.M.3    Yang, X.R.4    Yip, K.P.5    Tse, C.M.6    Sham, J.S.7
  • 10
    • 79951606631 scopus 로고    scopus 로고
    • The calcium-sensing receptor: A molecular perspective
    • 20729338
    • Magno AL, Ward BK, Ratajczak T (2010) The calcium-sensing receptor: a molecular perspective. Endocr Rev 32:3-30
    • (2010) Endocr Rev , vol.32 , pp. 3-30
    • Magno, A.L.1    Ward, B.K.2    Ratajczak, T.3
  • 11
    • 0038125588 scopus 로고    scopus 로고
    • Extracellular calcium sensing and signalling
    • 12838336 1:CAS:528:DC%2BD3sXltVWmsr4%3D
    • Hofer AM, Brown EM (2003) Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol 4:530-538
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 530-538
    • Hofer, A.M.1    Brown, E.M.2
  • 12
    • 0035138842 scopus 로고    scopus 로고
    • Extracellular calcium sensing and extracellular calcium signaling
    • 11152759 1:CAS:528:DC%2BD3MXitV2ktLo%3D
    • Brown EM, MacLeod RJ (2001) Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 81:239-297
    • (2001) Physiol Rev , vol.81 , pp. 239-297
    • Brown, E.M.1    Macleod, R.J.2
  • 13
    • 0038343513 scopus 로고    scopus 로고
    • Calcium and polyamine regulated calcium-sensing receptors in cardiac tissues
    • 12787035 1:CAS:528:DC%2BD3sXkvFSisr4%3D
    • Wang R, Xu C, Zhao W, Zhang J, Cao K, Yang B, Wu L (2003) Calcium and polyamine regulated calcium-sensing receptors in cardiac tissues. Eur J Biochem 270:2680-2688
    • (2003) Eur J Biochem , vol.270 , pp. 2680-2688
    • Wang, R.1    Xu, C.2    Zhao, W.3    Zhang, J.4    Cao, K.5    Yang, B.6    Wu, L.7
  • 15
    • 79961014900 scopus 로고    scopus 로고
    • Calcium-sensing receptor modulates extracellular Ca2+ entry via TRPC-encoded receptor-operated channels in human aortic smooth muscle cells
    • 21562303 1:CAS:528:DC%2BC3MXhtFSqurvM 3154552
    • Chow JY, Estrema C, Orneles T, Dong X, Barrett KE, Dong H (2011) Calcium-sensing receptor modulates extracellular Ca2+ entry via TRPC-encoded receptor-operated channels in human aortic smooth muscle cells. Am J Physiol Cell Physiol 301:C461
    • (2011) Am J Physiol Cell Physiol , vol.301 , pp. 461
    • Chow, J.Y.1    Estrema, C.2    Orneles, T.3    Dong, X.4    Barrett, K.E.5    Dong, H.6
  • 16
    • 24044516870 scopus 로고    scopus 로고
    • Evidence in favor of a calcium-sensing receptor in arterial endothelial cells studies with calindol and calhex 231
    • 16037572 1:CAS:528:DC%2BD2MXntlSiurw%3D
    • Weston AH, Absi M, Ward DT, Ohanian J, Dodd RH, Dauban P, Petrel C, Ruat M, Edwards G (2005) Evidence in favor of a calcium-sensing receptor in arterial endothelial cells studies with calindol and calhex 231. Circ Res 97:391-398
    • (2005) Circ Res , vol.97 , pp. 391-398
    • Weston, A.H.1    Absi, M.2    Ward, D.T.3    Ohanian, J.4    Dodd, R.H.5    Dauban, P.6    Petrel, C.7    Ruat, M.8    Edwards, G.9
  • 17
    • 84862189266 scopus 로고    scopus 로고
    • Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction
    • 22098336 1:CAS:528:DC%2BC38XotlCgs7w%3D
    • Zhang J, Zhou J, Cai L, Lu Y, Wang T, Zhu L, Hu Q (2012) Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction. Antioxid Redox Signal 17:471-484. doi: 10.1089/ars.2011.4168
    • (2012) Antioxid Redox Signal , vol.17 , pp. 471-484
    • Zhang, J.1    Zhou, J.2    Cai, L.3    Lu, Y.4    Wang, T.5    Zhu, L.6    Hu, Q.7
  • 19
    • 18844411578 scopus 로고    scopus 로고
    • Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery
    • 15665041 1:CAS:528:DC%2BD2MXlsVyltb8%3D
    • Wang J, Weigand L, Wang W, Sylvester JT, Shimoda LA (2005) Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery. Am J Physiol Lung Cell Mol Physiol 288:L1049-L1058. doi: 10.1152/ajplung.00379.2004
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. 1049-L1058
    • Wang, J.1    Weigand, L.2    Wang, W.3    Sylvester, J.T.4    Shimoda, L.A.5
  • 21
    • 84870253088 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor
    • 23108648 1:CAS:528:DC%2BC38Xhs1GqsrbN
    • Liu Y, Tian XY, Mao G, Fang X, Fung ML, Shyy JY, Huang Y, Wang N (2012) Peroxisome proliferator-activated receptor-gamma ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor. Hypertension 60:1471-1478. doi: 10.1161/HYPERTENSIONAHA.112.198887
    • (2012) Hypertension , vol.60 , pp. 1471-1478
    • Liu, Y.1    Tian, X.Y.2    Mao, G.3    Fang, X.4    Fung, M.L.5    Shyy, J.Y.6    Huang, Y.7    Wang, N.8
  • 22
    • 73349089620 scopus 로고    scopus 로고
    • Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling
    • 19823174 1:CAS:528:DC%2BD1MXhs1Wns7zJ
    • Sun Y, Tian Y, Prabha M, Liu D, Chen S, Zhang R, Liu X, Tang C, Tang X, Jin H, Du J (2010) Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling. Lab Invest 90:68-82. doi: 10.1038/labinvest.2009.102
    • (2010) Lab Invest , vol.90 , pp. 68-82
    • Sun, Y.1    Tian, Y.2    Prabha, M.3    Liu, D.4    Chen, S.5    Zhang, R.6    Liu, X.7    Tang, C.8    Tang, X.9    Jin, H.10    Du, J.11
  • 23
    • 20444432260 scopus 로고    scopus 로고
    • Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia
    • 15902302 1:CAS:528:DC%2BD2MXkvF2lsrY%3D 1090474
    • Nijenhuis T, Vallon V, van der Kemp AW, Loffing J, Hoenderop JG, Bindels RJ (2005) Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest 115:1651-1658. doi: 10.1172/JCI24134
    • (2005) J Clin Invest , vol.115 , pp. 1651-1658
    • Nijenhuis, T.1    Vallon, V.2    Van Der Kemp, A.W.3    Loffing, J.4    Hoenderop, J.G.5    Bindels, R.J.6
  • 24
    • 84902369145 scopus 로고    scopus 로고
    • Regulatory effect of AMP-activated protein kinase on pulmonary hypertension induced by chronic hypoxia in rats: In vivo and in vitro studies
    • Huang X, Fan R, Lu Y, Yu C, Xu X, Zhang X, Liu P, Yan S, Chen C, Wang L (2014) Regulatory effect of AMP-activated protein kinase on pulmonary hypertension induced by chronic hypoxia in rats: in vivo and in vitro studies. Mol Biol Rep. doi: 10.1007/s11033-014-3272-9
    • (2014) Mol Biol Rep
    • Huang, X.1    Fan, R.2    Lu, Y.3    Yu, C.4    Xu, X.5    Zhang, X.6    Liu, P.7    Yan, S.8    Chen, C.9    Wang, L.10
  • 25
    • 31344447802 scopus 로고    scopus 로고
    • Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates
    • 16266693 1:CAS:528:DC%2BD28XotVKiuw%3D%3D
    • Newby AC (2006) Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res 69:614-624. doi: 10.1016/j.cardiores.2005.08.002
    • (2006) Cardiovasc Res , vol.69 , pp. 614-624
    • Newby, A.C.1
  • 26
    • 79151478174 scopus 로고    scopus 로고
    • Circulating smooth muscle progenitor cells in arterial remodeling
    • 21047514 1:CAS:528:DC%2BC3MXhtlarsbg%3D
    • Daniel JM, Sedding DG (2011) Circulating smooth muscle progenitor cells in arterial remodeling. J Mol Cell Cardiol 50:273-279. doi: 10.1016/j.yjmcc.2010.10.030
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 273-279
    • Daniel, J.M.1    Sedding, D.G.2
  • 28
    • 84894330423 scopus 로고    scopus 로고
    • Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension
    • 23056939 3465915
    • Fernandez RA, Sundivakkam P, Smith KA, Zeifman AS, Drennan AR, Yuan JX (2012) Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension. J Signal Transduct 2012:951497. doi: 10.1155/2012/951497
    • (2012) J Signal Transduct , vol.2012 , pp. 951497
    • Fernandez, R.A.1    Sundivakkam, P.2    Smith, K.A.3    Zeifman, A.S.4    Drennan, A.R.5    Yuan, J.X.6
  • 29
    • 84858306938 scopus 로고    scopus 로고
    • New mechanisms of pulmonary arterial hypertension: Role of Ca(2+) signaling
    • 22245772 1:CAS:528:DC%2BC38XmvV2qtbc%3D 3330808
    • Kuhr FK, Smith KA, Song MY, Levitan I, Yuan JX (2012) New mechanisms of pulmonary arterial hypertension: role of Ca(2+) signaling. Am J Physiol Heart Circ Physiol 302:H1546-H1562. doi: 10.1152/ajpheart.00944.2011
    • (2012) Am J Physiol Heart Circ Physiol , vol.302 , pp. 1546-H1562
    • Kuhr, F.K.1    Smith, K.A.2    Song, M.Y.3    Levitan, I.4    Yuan, J.X.5
  • 30
    • 84868618365 scopus 로고    scopus 로고
    • Parathyroid hormone-independent role for the calcium-sensing receptor in the control of urinary calcium excretion
    • 23085632
    • Riccardi D (2012) Parathyroid hormone-independent role for the calcium-sensing receptor in the control of urinary calcium excretion. J Am Soc Nephrol 23:1766-1768. doi: 10.1681/ASN.2012090955
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1766-1768
    • Riccardi, D.1
  • 32
    • 79951736714 scopus 로고    scopus 로고
    • The calcium-sensing receptor mediates hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways
    • 21073657 1:CAS:528:DC%2BC3MXksFOlsrw%3D
    • Li GW, Xing WJ, Bai SZ, Hao JH, Guo J, Li HZ, Li HX, Zhang WH, Yang BF, Wu LY, Wang R, Yang GD, Xu CQ (2011) The calcium-sensing receptor mediates hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways. Basic Clin Pharmacol Toxicol 108:185-193. doi: 10.1111/j.1742-7843.2010.00639.x
    • (2011) Basic Clin Pharmacol Toxicol , vol.108 , pp. 185-193
    • Li, G.W.1    Xing, W.J.2    Bai, S.Z.3    Hao, J.H.4    Guo, J.5    Li, H.Z.6    Li, H.X.7    Zhang, W.H.8    Yang, B.F.9    Wu, L.Y.10    Wang, R.11    Yang, G.D.12    Xu, C.Q.13
  • 33
    • 67649644366 scopus 로고    scopus 로고
    • Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension
    • 19498269 1:CAS:528:DC%2BD1MXotFKhsLY%3D
    • Aoshima D, Murata T, Hori M, Ozaki H (2009) Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension. J Pharmacol Sci 110:182-190
    • (2009) J Pharmacol Sci , vol.110 , pp. 182-190
    • Aoshima, D.1    Murata, T.2    Hori, M.3    Ozaki, H.4
  • 34
    • 77649099042 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin
    • 20019333 1:CAS:528:DC%2BC3cXitFCks7g%3D
    • Wang L, Zheng J, Du Y, Huang Y, Li J, Liu B, Liu CJ, Zhu Y, Gao Y, Xu Q, Kong W, Wang X (2010) Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin. Circ Res 106:514-525. doi: 10.1161/CIRCRESAHA.109.202762
    • (2010) Circ Res , vol.106 , pp. 514-525
    • Wang, L.1    Zheng, J.2    Du, Y.3    Huang, Y.4    Li, J.5    Liu, B.6    Liu, C.J.7    Zhu, Y.8    Gao, Y.9    Xu, Q.10    Kong, W.11    Wang, X.12
  • 35
    • 84655162225 scopus 로고    scopus 로고
    • Over-expression of PKGIα inhibits hypoxia-induced proliferation, Akt activation, and phenotype modulation of human PASMCs: The role of phenotype modulation of PASMCs in pulmonary vascular remodeling
    • 22101188 1:CAS:528:DC%2BC38XmtlKq
    • Yi B, Cui J, Ning JN, Wang GS, Qian GS, Lu KZ (2012) Over-expression of PKGIα inhibits hypoxia-induced proliferation, Akt activation, and phenotype modulation of human PASMCs: the role of phenotype modulation of PASMCs in pulmonary vascular remodeling. Gene 492:354-360. doi: 10.1016/j.gene.2011.11.010
    • (2012) Gene , vol.492 , pp. 354-360
    • Yi, B.1    Cui, J.2    Ning, J.N.3    Wang, G.S.4    Qian, G.S.5    Lu, K.Z.6
  • 36
    • 84874954441 scopus 로고    scopus 로고
    • Rho-associated protein kinase isoforms stimulate proliferation of vascular smooth muscle cells through ERK and induction of cyclin D1 and PCNA
    • 23402758 1:CAS:528:DC%2BC3sXjtlyrt78%3D
    • Zhao Y, Lv M, Lin H, Cui Y, Wei X, Qin Y, Kohama K, Gao Y (2013) Rho-associated protein kinase isoforms stimulate proliferation of vascular smooth muscle cells through ERK and induction of cyclin D1 and PCNA. Biochem Biophys Res Commun 432:488-493. doi: 10.1016/j.bbrc.2013.02.009
    • (2013) Biochem Biophys Res Commun , vol.432 , pp. 488-493
    • Zhao, Y.1    Lv, M.2    Lin, H.3    Cui, Y.4    Wei, X.5    Qin, Y.6    Kohama, K.7    Gao, Y.8
  • 38
    • 70349250221 scopus 로고    scopus 로고
    • Signaling pathways regulating vascular smooth muscle cell differentiation
    • 19426604
    • Rzucidlo EM (2009) Signaling pathways regulating vascular smooth muscle cell differentiation. Vascular 17(Suppl 1):S15-S20
    • (2009) Vascular , vol.17 , pp. 15-S20
    • Rzucidlo, E.M.1
  • 40
    • 84878545864 scopus 로고    scopus 로고
    • Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells
    • 23531616 1:CAS:528:DC%2BC3sXpt1yjtL0%3D
    • Avlani VA, Ma W, Mun HC, Leach K, Delbridge L, Christopoulos A, Conigrave AD (2013) Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells. Am J Physiol Endocrinol Metab 304:E1097-E1104. doi: 10.1152/ajpendo.00054.2013
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. 1097-E1104
    • Avlani, V.A.1    Ma, W.2    Mun, H.C.3    Leach, K.4    Delbridge, L.5    Christopoulos, A.6    Conigrave, A.D.7
  • 41
    • 84878402940 scopus 로고    scopus 로고
    • Role of the calcium-sensing receptor in cardiomyocyte apoptosis via the sarcoplasmic reticulum and mitochondrial death pathway in cardiac hypertrophy and heart failure
    • 23711498
    • Lu FH, Fu SB, Leng X, Zhang X, Dong S, Zhao YJ, Ren H, Li H, Zhong X, Xu CQ, Zhang WH (2013) Role of the calcium-sensing receptor in cardiomyocyte apoptosis via the sarcoplasmic reticulum and mitochondrial death pathway in cardiac hypertrophy and heart failure. Cell Physiol Biochem 31:728-743. doi: 10.1159/000350091
    • (2013) Cell Physiol Biochem , vol.31 , pp. 728-743
    • Lu, F.H.1    Fu, S.B.2    Leng, X.3    Zhang, X.4    Dong, S.5    Zhao, Y.J.6    Ren, H.7    Li, H.8    Zhong, X.9    Xu, C.Q.10    Zhang, W.H.11
  • 42
    • 57649200121 scopus 로고    scopus 로고
    • Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis
    • 19088423 1:CAS:528:DC%2BD1cXhsV2lt7bN
    • Molostvov G, Fletcher S, Bland R, Zehnder D (2008) Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis. Cell Physiol Biochem 22:413-422. doi: 10.1159/000185484
    • (2008) Cell Physiol Biochem , vol.22 , pp. 413-422
    • Molostvov, G.1    Fletcher, S.2    Bland, R.3    Zehnder, D.4


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