Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction

Antioxidants and Redox Signaling

Volumn 17, Issue 3, 2012, Pages 471-484

  Zhang, Jiwei ^a   Zhou, Juan ^a   Cai, Lei ^a   Lu, Yankai ^a   Wang, Tao ^a   Zhu, Liping ^a   Hu, Qinghua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMIMETIC AGENT; CALCIUM SENSING RECEPTOR; CALHEX231; CATALASE; HYDROGEN PEROXIDE; MACROGOL; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR 3; SHORT HAIRPIN RNA; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; HYPOXIA; HYPOXIC LUNG VASOCONSTRICTION; LUNG HEMODYNAMICS; MEMBRANE PERMEABILITY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ANIMALS; BENZAMIDES; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CELL HYPOXIA; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOHEXYLAMINES; GENE KNOCKDOWN TECHNIQUES; HYDROGEN PEROXIDE; ISOQUINOLINES; MACROCYCLIC COMPOUNDS; MITOCHONDRIA; MYOCYTES, SMOOTH MUSCLE; OXAZOLES; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING; RNA INTERFERENCE; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SULFONAMIDES; VASOCONSTRICTION;

EID: 84862189266     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2011.4168     Document Type: Article

References (50)

1. + channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res 95: 308-318, 2004.
2. Bai M, Trivedi S, and Brown EM. Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells. J Biol Chem 273: 23605-23610, 1998. (Pubitemid 28417555)
3. 2+ concentration of myocytes isolated from different regions of the rat pulmonary arterial tree. Exp Physiol 83: 337-347, 1998.
4. 2+ exchange in hypoxic pulmonary vasoconstriction in rat intrapulmonary arteries. Novartis Found Symp 272: 259-268; discussion 268-279, 2006.
5. 2+ - sensing receptor from bovine parathyroid. Nature 366: 575-580, 1993.
6. 2+ -sensing receptor in rat intestine. Am J Physiol 274: G122-G130, 1998.
7. 2. Am J Physiol Lung Cell Mol Physiol 298: L178-L188, 2010.
8. Cornfield DN, Stevens T, McMurtry IF, Abman SH, and Rodman DM. Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells. Am J Physiol 266: L469-L475, 1994.
9. Cornfield DN, Stevens T, McMurtry IF, Abman SH, and Rodman DM. Acute hypoxia increases cytosolic calcium in fetal pulmonary artery smooth muscle cells. Am J Physiol 265: L53-L56, 1993. (Pubitemid 23227011)
10. 2+ in pulmonary artery smooth muscle cells of mouse lungs slices. Antioxid Redox Signal 12: 595-602, 2010.
11. Du W, Frazier M, McMahon TJ, and Eu JP. Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction. Chest 128: 556S-558S, 2005. (Pubitemid 43054116)
12. 2+ release from intracellular stores is an initial step in hypoxic pulmonary vasoconstriction of rat pulmonary artery resistance vessels. Circulation 96: 3647-3654, 1997.
13. 2+-dependent action potentials in small pulmonary arteries of the cat. J Appl Physiol 59: 1389-1393, 1985.
14. Hofer AM and Brown EM. Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol 4: 530-538, 2003. (Pubitemid 36773405)
15. 2+ release in hypoxic vasoconstriction of canine pulmonary artery. Br J Pharmacol 122: 21-30, 1997.
16. Leach RM, Hill HM, Snetkov VA, Robertson TP, and Ward JP. Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor. J Physiol 536: 211-224, 2001. (Pubitemid 32952231)
17. Li GW, Wang QS, Hao JH, Xing WJ, Guo J, Li HZ, Bai SZ, Li HX, Zhang WH, Yang BF, Yang GD, Wu LY, Wang R, and Xu CQ. The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells. J Biomed Sci 18: 16, 2010.
18. 2+ mobilization in pulmonary arterial smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 292: L1598-L1608, 2007.
19. Liu Q, Sham JS, Shimoda LA, and Sylvester JT. Hypoxic constriction of porcine distal pulmonary arteries: endothelium and endothelin dependence. Am J Physiol Lung Cell Mol Physiol 280: L856-L865, 2001.
20. Mauban JR, Remillard CV, and Yuan JX. Hypoxic pulmonary vasoconstriction: role of ion channels. J Appl Physiol 98: 415-420, 2005. (Pubitemid 40041275)
21. Molostvov G, Fletcher S, Bland R, and Zehnder D. Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis. Cell Physiol Biochem 22: 413-422, 2008.
22. 2+ entry pathways activated by store-depletion or hypoxia in canine pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol 294: C313-C323, 2008.
23. 2+ entry in isolated canine pulmonary arterial smooth muscle cells. J Physiol 563: 409-419, 2005.
24. Oda Y, Tu CL, Pillai S, and Bikle DD. The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation. J Biol Chem 273: 23344-23352, 1998. (Pubitemid 28417522)
25. i to hypoxia in pulmonary arterial smooth muscle. Am J Physiol Lung Cell Mol Physiol 283: L1143-L1150, 2002.
26. Paddenberg R, Ishaq B, Goldenberg A, Faulhammer P, Rose F, Weissmann N, Braun-Dullaeus RC, and Kummer W. Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature. Am J Physiol Lung Cell Mol Physiol 284: L710-L719, 2003. (Pubitemid 36459016)
27. cyt in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 293: L402-L416, 2007.
28. 2+ sensitization. Am J Physiol 268: H301-H307, 1995.
29. Robertson TP, Hague D, Aaronson PI, and Ward JP. Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat. J Physiol 525(Pt 3): 669-680, 2000. (Pubitemid 30426788)
30. Roy S, Parinandi N, Zeigelstein R, Hu Q, Pei Y, Travers JB, and Natarajan V. Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells. Antioxid Redox Signal 5: 217-228, 2003. (Pubitemid 36457597)
31. 2+ sparks in rat vascular smooth muscle cells. J Physiol 576: 887-901, 2006.
32. Russell MJ, Pelaez NJ, Packer CS, Forster ME, and Olson KR. Intracellular and extracellular calcium utilization during hypoxic vasoconstriction of cyclostome aortas. Am J Physiol Regul Integr Comp Physiol 281: R1506-R1513, 2001.
33. Sommer N, Dietrich A, Schermuly RT, Ghofrani HA, Gudermann T, Schulz R, Seeger W, Grimminger F, and Weissmann N. Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms. Eur Respir J 32: 1639-1651, 2008.
34. 2+ in pulmonary and cerebral arterial myocytes. Am J Physiol 265: L591-L597, 1993.
35. 2+ entry. Am J Physiol Lung Cell Mol Physiol 288: L1059-L1069, 2005.
36. Wang T, Zhang ZX, Xu YJ, andHuQH. 5-Hydroxydecanoate inhibits proliferation of hypoxic human pulmonary artery smooth muscle cells by blocking mitochondrial KATP channels. Acta Pharmacol Sin 28: 1531-1540, 2007. (Pubitemid 47493287)
37. 2+ responses in pulmonary artery myocytes. Antioxid Redox Signal 12: 611-623, 2010.
38. Ward JP and McMurtry IF. Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem. Curr Opin Pharmacol 9: 287-296, 2009.
39. Waypa GB, Chandel NS, and Schumacker PT. Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. Circ Res 88: 1259-1266, 2001. (Pubitemid 32587842)
40. Waypa GB, Marks JD, Guzy R, Mungai PT, Schriewer J, Dokic D, and Schumacker PT. Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells. Circ Res 106: 526-535, 2010.
41. Waypa GB, Marks JD, Mack MM, Boriboun C, Mungai PT, and Schumacker PT. Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circ Res 91: 719-726, 2002. (Pubitemid 35204955)
42. 2+ and nonselective cation channels. Am J Physiol Lung Cell Mol Physiol 289: L5-L13, 2005.
43. Weir EK, Cabrera JA, Mahapatra S, Peterson DA, and Hong Z. The role of ion channels in hypoxic pulmonary vasoconstriction. Adv Exp Med Biol 661: 3-14, 2010.
44. Weissberg PL, Little PJ, and Bobik A. Spontaneous oscillations in cytoplasmic calcium concentration in vascular smooth muscle. Am J Physiol 256: C951-C957, 1989.
45. Wonneberger K, Scofield MA, and Wangemann P. Evidence for a calcium-sensing receptor in the vascular smooth muscle cells of the spiral modiolar artery. J Membr Biol 175: 203-212, 2000. (Pubitemid 30421891)
46. i in canine cerebral arterial smooth muscle: participation of cellular signaling pathways. Naunyn Schmiedebergs Arch Pharmacol 360: 646-653, 1999.
47. Zhang Z, Sun S, Quinn SJ, Brown EM, and Bai M. The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions. J Biol Chem 276: 5316-5322, 2001.
48. Zheng YM, Wang QS, Rathore R, Zhang WH, Mazurkiewicz JE, Sorrentino V, Singer HA, Kotlikoff MI, and Wang YX. Type-3 ryanodine receptors mediate hypoxia-, but not neurotransmitter- induced calcium release and contraction in pulmonary artery smooth muscle cells. J Gen Physiol 125: 427-440, 2005.
49. 2+ oscillation frequency regulates agonist-stimulated gene expression in vascular endothelial cells. J Cell Sci 121: 2511-2518, 2008.
50. Ziegelstein RC, Xiong Y, He C, and Hu Q. Expression of a functional extracellular calcium-sensing receptor in human aortic endothelial cells. Biochem Biophys Res Commun 342: 153-163, 2006. (Pubitemid 43247372)