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Volumn 87, Issue , 2014, Pages 228-236
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β-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents
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Author keywords
Anticancer activity; Apoptosis; Cytotoxic activity; Endoperoxides
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Indexed keywords
8 [2 (1 NAPTHYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (3,4 DICHLORO PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (3,4 DIMETHOXY PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (3,4,5 TRIMETHOXY PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (O BROMO PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (O CHLORO PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6] DODEC 11 ENE;
8 [2 (O FLUORO PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (O METHOXY PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (O METHYL PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
8 [2 (O NITRO PHENYL) ETHENYL] 2,2,6 TRIMETHYL 7,9,10 TRIOXA TRICYCLO[6.2.2.0 1,6]DODEC 11 ENE;
ANTINEOPLASTIC AGENT;
BETA IONONE;
CASPASE 3;
CASPASE 9;
CELL NUCLEUS DNA;
CHALCONE DERIVATIVE;
ENDOPEROXIDE;
LACTATE DEHYDROGENASE;
REACTIVE OXYGEN METABOLITE;
UNCLASSIFIED DRUG;
BETA-IONONE;
DNA;
NORISOPRENOID;
PEROXIDE;
ANTINEOPLASTIC ACTIVITY;
APOPTOSIS;
ARTICLE;
CANCER INHIBITION;
CHO CELL LINE;
CYTOTOXICITY;
DRUG SYNTHESIS;
FLOW CYTOMETRY;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
LUNG CANCER CELL LINE;
MITOCHONDRIAL MEMBRANE POTENTIAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
ANIMAL;
CELL SURVIVAL;
CHEMISTRY;
CRICETULUS;
DRUG DESIGN;
DRUG EFFECTS;
HAMSTER;
INTRACELLULAR SPACE;
METABOLISM;
TUMOR CELL LINE;
ANIMALS;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
CASPASE 3;
CASPASE 9;
CELL LINE, TUMOR;
CELL SURVIVAL;
CHO CELLS;
CRICETINAE;
CRICETULUS;
DNA;
DRUG DESIGN;
HUMANS;
INTRACELLULAR SPACE;
L-LACTATE DEHYDROGENASE;
MEMBRANE POTENTIAL, MITOCHONDRIAL;
NORISOPRENOIDS;
PEROXIDES;
REACTIVE OXYGEN SPECIES;
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EID: 84907575827
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2014.09.049 Document Type: Article |
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Times cited : (14)
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References (34)
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