Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein

Journal of Infectious Diseases

Volumn 209, Issue 7, 2014, Pages 1116-1125

  Mann, Beth ^a   Thornton, Justin ^a   Heath, Richard ^a   Wade, Kristin R ^b   Tweten, Rodney K ^b   Gao, Geli ^a   El Kasmi, Karim ^a   Jordan, John B ^a   Mitrea, Diana M ^a   Kriwacki, Richard ^a   Maisonneuve, Jeff ^c   Alderson, Mark ^c   Tuomanen, Elaine I ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c PATH   (United States)

Author keywords

meningitis; meningococcus; pneumonia; Streptococcus pneumoniae; vaccine

Indexed keywords

CHOLINE BINDING PROTEIN A PNEUMOLYSOID FUSION PROTEIN; IMMUNOGLOBULIN G ANTIBODY; PNEUMOCOCCUS VACCINE; UNCLASSIFIED DRUG;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BACTEREMIA; BACTERIUM CARRIER; CONTROLLED STUDY; CROSS PROTECTION; FEMALE; HAEMOPHILUS INFLUENZAE; IMMUNOGENICITY; MENINGITIS; MENINGOCOCCEMIA; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OTITIS MEDIA; PASSIVE IMMUNIZATION; PNEUMONIA; PRIORITY JOURNAL; SEPSIS; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME;

MENINGITIS; MENINGOCOCCUS; PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; VACCINE;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; CARRIER STATE; CROSS PROTECTION; DISEASE MODELS, ANIMAL; FEMALE; HAEMOPHILUS INFLUENZAE; MICE; MICE, INBRED BALB C; NEISSERIA MENINGITIDIS; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; RECOMBINANT FUSION PROTEINS; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS; TOXOIDS; VACCINES, SYNTHETIC;

EID: 84898964001     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jit502     Document Type: Article

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