The Tandem Repeats Enabling Reversible Switching between the Two Phases of β-Lactamase Substrate Spectrum

PLoS Genetics

Volumn 10, Issue 9, 2014, Pages

  Yi, Hyojeong ^a   Song, Han ^a   Hwang, Junghyun ^a   Kim, Karan ^a   Nierman, William C ^b   Kim, Heenam Stanley ^a  

^a Department of Biosystems and Biotechnology University ^*  (South Korea)

^b J CRAIG VENTER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; ANTIINFECTIVE AGENT; CEFTAZIDIME;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENOME; BACTERIAL SURVIVAL; BETA LACTAMASE GENE; CONTROLLED STUDY; ENZYME SUBSTRATE; EVOLUTIONARY ADAPTATION; GENE DUPLICATION; GENE SEQUENCE; GENE STRUCTURE; GENE SWITCHING; GENETIC CODE; NONHUMAN; PHYLOGENY; POINT MUTATION; TANDEM REPEAT; ALLELE; BACTERIUM; BIOLOGICAL MODEL; DRUG EFFECTS; ENZYME SPECIFICITY; EVOLUTION; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

ALLELES; ANTI-BACTERIAL AGENTS; BACTERIA; BASE SEQUENCE; BETA-LACTAMASES; BIOLOGICAL EVOLUTION; CEFTAZIDIME; GENE DUPLICATION; GENOME, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHYLOGENY; POINT MUTATION; SUBSTRATE SPECIFICITY; TANDEM REPEAT SEQUENCES;

EID: 84907572304     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004640     Document Type: Article

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