Insertion mutagenesis as a tool in the modification of protein function. Extended substrate specificity conferred by pentapeptide insertions in the Ω-loop of TEM-1 β-lactamase

Journal of Biological Chemistry

Volumn 272, Issue 46, 1997, Pages 28833-28836

  Hayes, Finbarr ^a   Hallet, Bernard ^a   Cao, Yunhong ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; PENTAPEPTIDE;

ANTIBIOTIC RESISTANCE; ARTICLE; ENZYME MODIFICATION; ENZYME SPECIFICITY; GENE INSERTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BETA-LACTAMASES; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; SUBSTRATE SPECIFICITY;

EID: 0030669944     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.46.28833     Document Type: Article

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