Naringin prevents ovariectomy-induced osteoporosis and promotes osteoclasts apoptosis through the mitochondria-mediated apoptosis pathway

Biochemical and Biophysical Research Communications

Volumn 452, Issue 3, 2014, Pages 629-635

  Li, Fengbo ^a,b   Sun, Xiaolei ^a   Ma, Jianxiong ^a   Ma, Xinlong ^a   Zhao, Bin ^a   Zhang, Yang ^a   Tian, Peng ^a   Li, Yanjun ^b   Han, Zhe ^a  

^a Tianjin Hospital   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Naringin; Osteoclast; Osteoporosis

Indexed keywords

AURANTIIN; CASPASE 3; CYTOCHROME C; ESTRADIOL; PROTEIN BAX; PROTEIN BCL 2; BONE DENSITY CONSERVATION AGENT; FLAVANONE DERIVATIVE; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MINERALIZATION; CONTROLLED STUDY; CORNEA THICKNESS; DOWN REGULATION; FEMALE; IN VITRO STUDY; MITOCHONDRION; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OVARIECTOMY-INDUCED OSTEOPOROSIS; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BONE DENSITY; CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; OSTEOPOROSIS; OVARIECTOMY; PATHOLOGY; PREVENTION AND CONTROL; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; BONE RESORPTION; CALCIFICATION, PHYSIOLOGIC; CASPASE 3; CELL LINE; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAVANONES; GENE EXPRESSION; HUMANS; MITOCHONDRIA; OSTEOCLASTS; OSTEOPOROSIS; OVARIECTOMY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84907551903     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.117     Document Type: Article

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