Turmeric (Curcuma longa L.) the Indian Golden Curry Spice as a skin care agent: Validation of the traditional uses

Bioactive Dietary Factors and Plant Extracts in Dermatology

Volumn , Issue , 2013, Pages 93-102

  Baliga, Manjeshwar Shrinath ^a   Venkatesh, Sunitha ^a   Mrinal, Shilpa ^a   Bala, Nandakishore ^a   Palatty, Princy Louis ^a  

^a FATHER MULLER MEDICAL COLLEGE   (India)

Author keywords

Ageing; Chemical carcinogenesis; Curcuma longa; Psoriasis; UV induced skin damage; Wound healing

Indexed keywords

EID: 84907549852     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-62703-167-7_10     Document Type: Chapter

References (55)

1. Eigner D, Scholz D. Ferula asa-foetida and Curcuma longa in traditional medicinal treatment and diet in Nepal. J Ethnopharmacol. 1999;67:1-6.
2. Ishita C, Kaushik B, Uday B, et al. Turmeric and curcumin: biological actions and medicinal applications. Curr Sci. 2004;87:44-53.
3. Selvan R, Subramanian L, Gayathri R, et al. The antioxidant activity of turmeric ( Curcuma longa ). J Ethnopharmacol. 1995;47:59-65.
4. Thomas JL, Robert AS. Common skin disorders. In: Wilson JD, Wilson JD, Isselbacher KJ, et al., editors. Harrison's principles of internal medicine. 12th ed. New York: Mc Graw-Hill, Inc.; 1991. p. 309.
5. Heng MC, Song MK, Harker J, et al. Drug-induced suppression of phosphorylase kinase activity correlates with resolution of psoriasis as assessed by clinical, histological and immunohistochemical parameters. Br J Dermatol. 2000;143:937-49.
6. Pol A, Bergers M, Schalkwijk J. Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay. In Vitro Cell Dev Biol Anim. 2003;39:36-42.
7. Cho JW, Lee KS, Kim CW. Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med. 2007;19:469-74.
8. Saelee C, Thongrakard V, Tencomnao T. Effects of Thai medicinal herb extracts with anti-psoriatic activity on the expression on NF-k B signaling biomarkers in HaCaT keratinocytes. Molecules. 2011;16:3908-32.
9. Simandi C. Alteration in skin function and integrity. In: Porth CM, editor. Pathophysiology, concepts of altered health states. 3rd ed. USA: JB Lippincott Company; 1990. p. 108-40.
10. Kundu S, Biswas TK, Das P, et al. Turmeric ( Curcuma longa ) rhizome paste and honey show similar wound healing potential: a preclinical study in rabbits. Int J Low Extrem Wounds. 2005;4:205-13.
11. Khare P, Khare S, Goswami RB, et al. Evaluation of comparative effect of intact plant formulation and its polyherbal formulation for wound healing activity. Plant Archiv. 2010;10:671-4.
12. Srimal RC, Dhawan BN. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-in fl ammatory agent. J Pharm Pharmacol. 1973;25:447-52.
13. Sidhu GS, Singh AK, Thaloor D, et al. Enhancement of wound healing by curcumin in animals. Wound Repair Regen. 1998;6:167-77.
14. Gopinath D, Ahmed MR, Gomathi K, et al. Dermal wound healing processes with curcumin incorporated collagen fi lms. Biomaterials. 2004;25:1911-7.
15. Demirovic D, Rattan SI. Curcumin induces stress response and hormetically modulates wound healing ability of human skin fi broblasts undergoing ageing in vitro. Biogerontology. 2011;12(5):437-44.
16. Scharstuhl A, Mutsaers HA, Pennings SW, et al. Curcumin-induced fi broblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation. J Cell Mol Med. 2009;13:712-25.
17. Singer AJ, McClain SA, Romanov A, et al. Curcumin reduces burn progression in rats. Acad Emerg Med. 2007;14:1125-9.
18. Sajithlal GB, Chithra P, Chandrakasan G. Effect of curcumin on the advanced glycation and cross-linking of collagen in diabetic rats. Biochem Pharmacol. 1998;56:1607-14.
19. Mani H, Sidhu GS, Kumari R, et al. Curcumin differentially regulates TGF-beta1, its receptors and nitric oxide synthase during impaired wound healing. Biofactors. 2002;16:29-43.
20. Jagetia GC, Rajanikant GK. Effect of curcumin on radiation-impaired healing of excisional wounds in mice. J Wound Care. 2004;13:107-9.
21. Jagetia GC, Rajanikant GK. Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of gamma-radiation. J Surg Res. 2004;120:127-38.
22. Jagetia GC, Rajanikant GK. Curcumin treatment enhances the repair and regeneration of wounds in mice exposed to hemibody gamma-irradiation. Plast Reconstr Surg. 2005;115:515-28.
23. Okunieff P, Xu J, Hu D, et al. Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of in fl ammatory and fi brogenic cytokines. Int J Radiat Oncol Biol Phys. 2006;65:890-8.
24. Chen QM, Bartholomew JC, Campisi J, et al. Molecular analysis of H 2 O 2 -induced senescent-like growth arrest in normal human fi broblasts: p53 and Rb control G1 arrest but not cell replication. Biochem J. 1998;332(Pt 1):43-50.
25. Phan TT, See P, Lee ST, et al. Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing. J Trauma. 2001;51:927-31.
26. Lima CF, Pereira-Wilson C, Rattan SI. Curcumin induces heme oxygenase-1 in normal human skin fi broblasts through redox signaling: relevance for anti-aging intervention. Mol Nutr Food Res. 2011;55:430-42.
27. Ishizaki C, Oguro T, Yoshida T, et al. Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-O-tetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin. Dermatology. 1996;193:311-7.
28. Dujic J, Kippenberger S, Hoffmann S, et al. Low concentrations of curcumin induce growth arrest and apoptosis in skin keratinocytes only in combination with UVA or visible light. J Invest Dermatol. 2007;127:1992-2000.
29. Sumiyoshi M, Kimura Y. Effects of a turmeric extract ( Curcuma longa ) on chronic ultraviolet B irradiationinduced skin damage in melanin-possessing hairless mice. Phytomedicine. 2009;16:1137-43.
30. Agrawal R, Kaur IP. Inhibitory effect of encapsulated curcumin on ultraviolet-induced photoaging in mice. Rejuvenation Res. 2010;13:397-410.
31. Lu YP, Chang RL, Lou YR, et al. Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis. Carcinogenesis. 1994;15: 2363-70.
32. Cho JW, Park K, Kweon GR, et al. Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets. Exp Mol Med. 2005;37:186-92.
33. Asawanonda P, Klahan SO. Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study. Photomed Laser Surg. 2010;28:679-84.
34. Baliga MS, Katiyar SK. Chemoprevention of photocarcinogenesis by selected dietary botanicals. Photochem Photobiol Sci. 2006;5:243-53.
35. Azuine MA, Bhide SV. Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr Cancer. 1992;17:77-83.
36. Villaseñor IM, Simon MK, Villanueva AM. Comparative potencies of nutraceuticals in chemically induced skin tumor prevention. Nutr Cancer. 2002;44:66-70.
37. Kuttan R, Sudheeran PC, Josph CD. Turmeric and curcumin as topical agents in cancer therapy. Tumori. 1987;73: 29-31.
38. Limtrakul P, Lipigorngoson S, Namwong O, et al. Inhibitory effect of dietary curcumin on skin carcinogenesis in mice. Cancer Lett. 1997;116:197-203.
39. Limtrakul P, Anuchapreeda S, Lipigorngoson S, et al. Inhibition of carcinogen induced c-Ha-ras and c-fos protooncogenes expression by dietary curcumin. BMC Cancer. 2001;1:1.
40. Huang MT, Smart RC, Wong CQ, et al. Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1988;48:5941-6.
41. Huang MT, Newmark HL, Frenkel K. Inhibitory effects of curcumin on tumorigenesis in mice. J Cell Biochem Suppl. 1997;27:26-34.
42. Conney AH, Lysz T, Ferraro T, et al. Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul. 1991;31:385-96.
43. Huang MT, Lysz T, Ferraro T, et al. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 1991;51:813-9.
44. Liu JY, Lin SJ, Lin JK. Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoylphorbol-13-acetate in NIH 3T3 cells. Carcinogenesis. 1993;14:857-61.
45. Lin JK, Chen YC, Huang YT, et al. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J Cell Biochem Suppl. 1997; 28-29:39-48.
46. Jiang MC, Yang-Yen HF, Yen JJ, et al. Curcumin induces apoptosis in immortalized NIH 3 T3 and malignant cancer cell lines. Nutr Cancer. 1996;26:111-20.
47. Lee SK, Pezzuto JM. Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity. Arch Pharm Res. 1999;22: 559-64.
48. Garg R, Ramchandani AG, Maru GB. Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin. Carcinogenesis. 2008;29:1249-57.
49. Huang MT, Ma W, Lu YP, et al. Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydro curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Carcinogenesis. 1995;16:2493-7.
50. Bonté F, Noel-Hudson MS, Wepierre J, et al. Protective effect of curcuminoids on epidermal skin cells under free oxygen radical stress. Planta Med. 1997;63:265-6.
51. Jee SH, Shen SC, Tseng CR, et al. Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells. J Invest Dermatol. 1998;111:656-61.
52. Marín YE, Wall BA, Wang S, et al. Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells. Melanoma Res. 2007;17:274-83.
53. Ray S, Chattopadhyay N, Mitra A, et al. Curcumin exhibits antimetastatic properties by modulating integrin receptors, collagenase activity, and expression of Nm23 and E-cadherin. J Environ Pathol Toxicol Oncol. 2003;22:49-58.
54. Santibáñez JF, Quintanilla M, Martínez J. Genistein and curcumin block TGF-b 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes. Nutr Cancer. 2000;37:49-54.
55. Cheng AL, Hsu CH, Lin JK, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001;21(4B):2895-900.