메뉴 건너뛰기




Volumn 452, Issue 3, 2014, Pages 567-574

Protocadherin 9 inhibits epithelial-mesenchymal transition and cell migration through activating GSK-3β in hepatocellular carcinoma

Author keywords

EMT; GSK 3 ; Hepatocellular carcinoma; Protocadherin 9; Tumor suppressor gene

Indexed keywords

CADHERIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTOCADHERIN 9; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PCDH9 PROTEIN, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84907533336     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.101     Document Type: Article
Times cited : (43)

References (30)
  • 1
    • 77955415514 scopus 로고    scopus 로고
    • Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma
    • M.C. Kew Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma Pathol. Biol. (Paris) 58 2010 273 277
    • (2010) Pathol. Biol. (Paris) , vol.58 , pp. 273-277
    • Kew, M.C.1
  • 2
    • 80053250896 scopus 로고    scopus 로고
    • Toward optimizing the indications for orthotopic liver transplantation in hepatocellular carcinoma
    • D. Samuel, M. Colombo, H. El-Serag, R. Sobesky, and N. Heaton Toward optimizing the indications for orthotopic liver transplantation in hepatocellular carcinoma Liver Transpl. 17 2011 S6 S13
    • (2011) Liver Transpl. , vol.17 , pp. S6-S13
    • Samuel, D.1    Colombo, M.2    El-Serag, H.3    Sobesky, R.4    Heaton, N.5
  • 3
  • 4
    • 0036674501 scopus 로고    scopus 로고
    • Metastasis: Dissemination and growth of cancer cells in metastatic sites
    • A.F. Chambers, A.C. Groom, and I.C. MacDonald Metastasis: dissemination and growth of cancer cells in metastatic sites Nat. Rev. Cancer 2 2002 563 572
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    Macdonald, I.C.3
  • 8
    • 0034657319 scopus 로고    scopus 로고
    • Cadherin superfamily genes: Functions, genomic organization, and neurologic diversity
    • T. Yagi, and M. Takeichi Cadherin superfamily genes: functions, genomic organization, and neurologic diversity Genes Dev. 14 2000 1169 1180
    • (2000) Genes Dev. , vol.14 , pp. 1169-1180
    • Yagi, T.1    Takeichi, M.2
  • 9
    • 35548999252 scopus 로고    scopus 로고
    • Protocadherin family: Diversity, structure, and function
    • H. Morishita, and T. Yagi Protocadherin family: diversity, structure, and function Curr. Opin. Cell Biol. 19 2007 584 592
    • (2007) Curr. Opin. Cell Biol. , vol.19 , pp. 584-592
    • Morishita, H.1    Yagi, T.2
  • 12
    • 84876316812 scopus 로고    scopus 로고
    • Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer
    • X. Zhong, Y. Zhu, J. Mao, J. Zhang, and S. Zheng Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer J. Cancer Res. Clin. Oncol. 139 2013 485 490
    • (2013) J. Cancer Res. Clin. Oncol. , vol.139 , pp. 485-490
    • Zhong, X.1    Zhu, Y.2    Mao, J.3    Zhang, J.4    Zheng, S.5
  • 13
    • 84872860185 scopus 로고    scopus 로고
    • Protocadherin 17 acts as a tumor suppressor inducing tumor cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers
    • X. Hu, X. Sui, L. Li, X. Huang, R. Rong, X. Su, Q. Shi, L. Mo, X. Shu, Y. Kuang, Q. Tao, and C. He Protocadherin 17 acts as a tumor suppressor inducing tumor cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers J. Pathol. 229 2013 62 73
    • (2013) J. Pathol. , vol.229 , pp. 62-73
    • Hu, X.1    Sui, X.2    Li, L.3    Huang, X.4    Rong, R.5    Su, X.6    Shi, Q.7    Mo, L.8    Shu, X.9    Kuang, Y.10    Tao, Q.11    He, C.12
  • 14
    • 33646422462 scopus 로고    scopus 로고
    • Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers
    • I. Imoto, H. Izumi, S. Yokoi, H. Hosoda, T. Shibata, F. Hosoda, M. Ohki, S. Hirohashi, and J. Inazawa Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers Cancer Res. 66 2006 4617 4626
    • (2006) Cancer Res. , vol.66 , pp. 4617-4626
    • Imoto, I.1    Izumi, H.2    Yokoi, S.3    Hosoda, H.4    Shibata, T.5    Hosoda, F.6    Ohki, M.7    Hirohashi, S.8    Inazawa, J.9
  • 17
    • 84856644382 scopus 로고    scopus 로고
    • Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma
    • Y. Wang, J. Cheng, C. Xu, S. Liu, S. Jiang, Q. Xu, X. Chen, H. Zhuang, and F. Lu Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma Liver Int. 32 2012 420 428
    • (2012) Liver Int. , vol.32 , pp. 420-428
    • Wang, Y.1    Cheng, J.2    Xu, C.3    Liu, S.4    Jiang, S.5    Xu, Q.6    Chen, X.7    Zhuang, H.8    Lu, F.9
  • 18
    • 84892911871 scopus 로고    scopus 로고
    • Selection of reference genes for RT-qPCR analysis in tumor tissues from male hepatocellular carcinoma patients with hepatitis B infection and cirrhosis
    • S. Liu, P. Zhu, L. Zhang, S. Ding, S. Zheng, Y. Wang, and F. Lu Selection of reference genes for RT-qPCR analysis in tumor tissues from male hepatocellular carcinoma patients with hepatitis B infection and cirrhosis Cancer Biomark. 13 2013 345 349
    • (2013) Cancer Biomark. , vol.13 , pp. 345-349
    • Liu, S.1    Zhu, P.2    Zhang, L.3    Ding, S.4    Zheng, S.5    Wang, Y.6    Lu, F.7
  • 19
    • 84921439240 scopus 로고    scopus 로고
    • PCDH20 functions as a tumour-suppressor gene through antagonizing the Wnt/b-catenin signalling pathway in hepatocellular carcinoma
    • (Epub ahead of print)
    • J. Lv, P. Zhu, Z. Yang, M. Li, X. Zhang, J. Cheng, X. Chen, and F. Lu PCDH20 functions as a tumour-suppressor gene through antagonizing the Wnt/b-catenin signalling pathway in hepatocellular carcinoma J. Viral Hepat. 2014 10.1111/jvh.12265 (Epub ahead of print)
    • (2014) J. Viral Hepat.
    • Lv, J.1    Zhu, P.2    Yang, Z.3    Li, M.4    Zhang, X.5    Cheng, J.6    Chen, X.7    Lu, F.8
  • 21
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • B.P. Zhou, J. Deng, W. Xia, J. Xu, Y.M. Li, M. Gunduz, and M.C. Hung Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition Nat. Cell Biol. 6 2004 931 940
    • (2004) Nat. Cell Biol. , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 22
    • 0028023861 scopus 로고
    • Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma
    • X. Zhang, H.J. Xu, Y. Murakami, R. Sachse, K. Yashima, S. Hirohashi, S.X. Hu, W.F. Benedict, and T. Sekiya Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma Cancer Res. 54 1994 4177 4182
    • (1994) Cancer Res. , vol.54 , pp. 4177-4182
    • Zhang, X.1    Xu, H.J.2    Murakami, Y.3    Sachse, R.4    Yashima, K.5    Hirohashi, S.6    Hu, S.X.7    Benedict, W.F.8    Sekiya, T.9
  • 23
    • 0033119604 scopus 로고    scopus 로고
    • Chromosome 13q deletion mapping in pituitary tumors: Infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas
    • D.J. Simpson, J. Magnay, J.E. Bicknell, A.L. Barkan, A.M. McNicol, R.N. Clayton, and W.E. Farrell Chromosome 13q deletion mapping in pituitary tumors: infrequent loss of the retinoblastoma susceptibility gene (RB1) locus despite loss of RB1 protein product in somatotrophinomas Cancer Res. 59 1999 1562 1566
    • (1999) Cancer Res. , vol.59 , pp. 1562-1566
    • Simpson, D.J.1    Magnay, J.2    Bicknell, J.E.3    Barkan, A.L.4    McNicol, A.M.5    Clayton, R.N.6    Farrell, W.E.7
  • 24
    • 0035992384 scopus 로고    scopus 로고
    • Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma
    • C.M. Wong, J.M. Lee, T.C. Lau, S.T. Fan, and I.O. Ng Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma Clin. Cancer Res. 8 2002 2266 2272
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2266-2272
    • Wong, C.M.1    Lee, J.M.2    Lau, T.C.3    Fan, S.T.4    Ng, I.O.5
  • 27
    • 27644473229 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition
    • D.C. Radisky Epithelial-mesenchymal transition J. Cell Sci. 118 2005 4325 4326
    • (2005) J. Cell Sci. , vol.118 , pp. 4325-4326
    • Radisky, D.C.1
  • 28
    • 0346363757 scopus 로고    scopus 로고
    • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
    • H. Peinado, E. Ballestar, M. Esteller, and A. Cano Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex Mol. Cell. Biol. 24 2004 306 319
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 306-319
    • Peinado, H.1    Ballestar, E.2    Esteller, M.3    Cano, A.4
  • 29
    • 78649676371 scopus 로고    scopus 로고
    • Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation
    • S. Biswas, M.R. Emond, and J.D. Jontes Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation J. Cell Biol. 191 2010 1029 1041
    • (2010) J. Cell Biol. , vol.191 , pp. 1029-1041
    • Biswas, S.1    Emond, M.R.2    Jontes, J.D.3
  • 30
    • 84856807290 scopus 로고    scopus 로고
    • A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion
    • M.R. Emond, S. Biswas, C.J. Blevins, and J.D. Jontes A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion J. Cell Biol. 195 2011 1115 1121
    • (2011) J. Cell Biol. , vol.195 , pp. 1115-1121
    • Emond, M.R.1    Biswas, S.2    Blevins, C.J.3    Jontes, J.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.