Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9

RNA Biology

Volumn 11, Issue 7, 2014, Pages 829-835

  Han, Jinxiong ^a   Zhang, Jun ^a   Chen, Li ^a   Shen, Bin ^a   Zhou, Jiankui ^a   Hu, Bian ^a   Du, Yinan ^a   Tate, Peri H ^c   Huang, Xingxu ^a   Zhang, Wensheng ^b,c  

^a NANJING UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

CRISPR Cas9; Imprinting; Large fragment deletion; LncRNA; Rian

Indexed keywords

LONG UNTRANSLATED RNA; RIAN PROTEIN; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; RIAN PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME 12; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION; GENETIC VARIABILITY; GENOME IMPRINTING; IN VIVO STUDY; KNOCKOUT GENE; MOUSE; NONHUMAN; ANIMAL; CHROMOSOME; CRISPR CAS SYSTEM; ECONOMICS; GENE TARGETING; GENETICS; METABOLISM; PROCEDURES;

ANIMALS; CHROMOSOMES, MAMMALIAN; CRISPR-CAS SYSTEMS; GENE DELETION; GENE TARGETING; GENOMIC IMPRINTING; MICE; NUCLEAR PROTEINS;

EID: 84907528008     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.29624     Document Type: Article

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