Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant

Organogenesis

Volumn 10, Issue 2, 2014, Pages 177-185

  Davey, Megan G ^a   McTeir, Lynn ^a   Barrie, Andrew M ^a   Freem, Lucy J ^a   Stephen, Louise A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cholestasis; Cilia; Ciliopathy; GLI; KIAA0586; Liver; Pulmonary Hypoplasia; SHH; Short rib polydactyly; TALPID3

Indexed keywords

PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; WNT5A PROTEIN; CELL CYCLE PROTEIN; CELL SURFACE RECEPTOR; PROTEIN PATCHED;

ANIMAL TISSUE; ARTICLE; CHICKEN; CHOLESTASIS; CHONDRODYSPLASIA; CILIOPATHY; CONTROLLED STUDY; EMBRYO; EUKARYOTIC FLAGELLUM; FETUS LUNG; GENETIC DISORDER; HEPATOBILIARY SYSTEM; LIVER DEVELOPMENT; LIVER FAILURE; LIVER FIBROSIS; LUNG DEVELOPMENT; LUNG HYPOPLASIA; MORPHOLOGY; MUTANT; NONHUMAN; PHENOTYPE; RIB; SIGNAL TRANSDUCTION; ABNORMALITIES; ANIMAL; CHICK EMBRYO; COMPLICATION; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIVER; LIVER CIRRHOSIS; LUNG; METABOLISM; MUTATION; PATHOLOGY;

ANIMALS; BILIARY TRACT; CELL CYCLE PROTEINS; CHICK EMBRYO; CHICKENS; CHOLESTASIS; CILIA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HUMANS; LIVER; LIVER CIRRHOSIS; LUNG; MUTATION; PATCHED RECEPTORS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 84907516357     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.28819     Document Type: Article

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