Hope and persuasion by physicians during informed consent

Journal of Clinical Oncology

Volumn 32, Issue 29, 2014, Pages 3229-3235

  Miller, Victoria A ^a   Cousino, Melissa ^b,c   Leek, Angela C ^d   Kodish, Eric D ^d  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BONE CANCER; BRAIN CANCER; CANCER PALLIATIVE THERAPY; CHILD; CHILDHOOD CANCER; DOCTOR PATIENT RELATION; EXPECTATION; FEMALE; HOPE; HUMAN; INFORMED CONSENT; INTERRATER RELIABILITY; INTERVIEW; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; NEUROBLASTOMA; PERSUASIVE COMMUNICATION; PHASE 1 CLINICAL TRIAL (TOPIC); PHYSICIAN; SOFT TISSUE CANCER; CLINICAL TRIAL; ETHICS; INTERPERSONAL COMMUNICATION; MULTICENTER STUDY; NEOPLASMS; PALLIATIVE THERAPY; PARENT; QUESTIONNAIRE; UNITED STATES; YOUNG ADULT;

ADOLESCENT; CHILD; CLINICAL TRIALS, PHASE I AS TOPIC; FEMALE; HOPE; HUMANS; INFORMED CONSENT; NEOPLASMS; PALLIATIVE CARE; PARENTS; PERSUASIVE COMMUNICATION; QUESTIONNAIRES; TRUTH DISCLOSURE; UNITED STATES; YOUNG ADULT;

EID: 84907499903     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.55.2588     Document Type: Article

References (31)

1. Agrawal M, Emanuel EJ: Ethics of phase 1 oncology studies: Reexamining the arguments and data. JAMA 290:1075-1082, 2003
2. Oberman M, Frader J: Dying children and medical research: Access to clinical trials as benefit and burden. Am J Law Med 29:301-317, 2003
3. Crites J, Kodish E: Unrealistic optimism and the ethics of phase I cancer research. J Med Ethics 39:403-406, 2013
4. Reder EA, Serwint JR: Until the last breath: Exploring the concept of hope for parents and health care professionals during a child's serious illness. Arch Pediatr Adolesc Med 163:653-657, 2009
5. Bluebond-Langner M, Belasco JB, Goldman A, et al: Understanding parents' approaches to care and treatment of children with cancer when standard therapy has failed. J Clin Oncol 25:2414-2419, 2007
6. Clayton JM, Butow PN, Arnold RM, et al: Fostering coping and nurturing hope when discussing the future with terminally ill cancer patients and their caregivers. Cancer 103:1965-1975, 2005
7. Clayton JM, Hancock K, Parker S, et al: Sustaining hope when communicating with terminally ill patients and their families: A systematic review. Psychooncology 17:641-659, 2008
8. Schneiderman LJ: The perils of hope. Camb Q Healthc Ethics 14:235-239, 2005
9. De Graves S, Aranda S: Living with hope and fear: The uncertainty of childhood cancer after relapse. Cancer Nurs 31:292-301, 2008
10. Salmon P, Hill J, Ward J, et al: Faith and protection: The construction of hope by parents of children with leukemia and their oncologists. Oncologist 17:398-404, 2012
11. Yap TY, Yamokoski AD, Hizlan S, et al: Informed consent for pediatric phase 1 cancer trials: Physicians' perspectives. Cancer 116:3244-3250, 2010
12. Gordon EJ, Daugherty CK: 'Hitting you over the head': Oncologists' disclosure of prognosis to advanced cancer patients. Bioethics 17:142-168, 2003
13. Cousino MK, Zyzanski SJ, Yamokoski AD, et al: Communicating and understanding the purpose of pediatric phase I cancer trials. J Clin Oncol 30:4367-4372, 2012
14. Erlandson DA, Harris EL, Skipper BL, et al: Doing Naturalistic Inquiry: A Guide to Methods. Newbury Park, CA, Sage Publications, 1993
15. Lincoln YS, Guba EG: Naturalistic Inquiry. Beverly Hills, CA, Sage Publications, 1985
16. Landis JR, Koch GG: The measurement of observer agreement for categorical data. Biometrics 33:159-174, 1977
17. Lee DP, Skolnik JM, Adamson PC: Pediatric phase I trials in oncology: An analysis of study conduct efficiency. J Clin Oncol 23:8431-8441, 2005
18. Shah S, Weitman S, Langevin AM, et al: Phase I therapy trials in children with cancer. J Pediatr Hematol Oncol 20:431-438, 1998
19. National Cancer Institute: National Cancer Institute fact sheet: Cancer clinical trials. http://www.cancer.gov/cancertopics/factsheet/clinicaltrials/clinical-trials
20. Kodish E, Post SG: Oncology and hope. J Clin Oncol 13:1817-1822, 1995
21. Kass N, Taylor H, Fogarty L, et al: Purpose and benefits of early phase cancer trials: What do oncologists say? What do patients hear? J Empir Res Hum Res Ethics 3:57-68, 2008
22. Sankar P: Communication and miscommunication in informed consent to research. Med Anthropol Q 18:429-446, 2004
23. Wolfe J, Klar N, Grier HE, et al: Understanding of prognosis among parents of children who died of cancer: Impact on treatment goals and integration of palliative care. JAMA 284:2469-2475, 2000
24. Wolfe J, Grier HE, Klar N, et al: Symptoms and suffering at the end of life in children with cancer. N Engl J Med 342:326-333, 2000
25. Code of Federal Regulations: Protection of human subjects. 45 CFR 46. 116. 2009. http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.html
26. Wrosch C, Scheier MF, Miller GE, et al: Adaptive self-regulation of unattainable goals: Goal disengagement, goal reengagement, and subjective well-being. Pers Soc Psychol Bull 29:1494-1508, 2003
27. Gum A, Snyder CR: Coping with terminal illness: The role of hopeful thinking. J Palliat Med 5:883-894, 2002
28. Hill DL, Miller V, Walter JK, et al: Regoaling: A conceptual model of how parents of children with serious illness change medical care goals. BMC Palliat Care 13:9, 2014
29. Steele AC, Kaal J, Thompson AL, et al: Bereaved parents and siblings offer advice to health care providers and researchers. J Pediatr Hematol Oncol 35:253-259, 2013
30. Brown R, Bylund CL, Siminoff LA, et al: Seeking informed consent to phase I cancer clinical trials: Identifying oncologists communication strategies. Psychooncology 20:361-368, 2011
31. Baker JN, Leek AC, Salas HS, et al: Suggestions from adolescents, young adults, and parents for improving informed consent in phase 1 pediatric oncology trials. Cancer 119:4154-4161, 2013