-
1
-
-
0031016857
-
Critical role of phase I clinical trials in cancer treatment
-
Ratain MJ, Collyar D, Kamen B, et al. Critical role of phase I clinical trials in cancer treatment. J Clin Oncol 1997;15:853-9.
-
(1997)
J Clin Oncol
, vol.15
, pp. 853-859
-
-
Ratain, M.J.1
Collyar, D.2
Kamen, B.3
-
3
-
-
0018971138
-
Phase I clinical and pharmacokinetic study of 4′(9-Acridinylamino)-methanesulfon-m-anisidide in children with cancer
-
Rivera G, Evans WE, Dahl GV, et al. Phase I clinical and pharmacokinetic study of 4′(9-Acridinylamino)-methanesulfon-m-anisidide in children with cancer. Cancer Res 1980;40:4250-3.
-
(1980)
Cancer Res
, vol.40
, pp. 4250-4253
-
-
Rivera, G.1
Evans, W.E.2
Dahl, G.V.3
-
4
-
-
0027081810
-
Phase I and pharmacokinetic evaluation of All-Trans-Retinoic Acid in pediatric patients with cancer
-
Smith MA, Adamson PC, Balis FM, et al. Phase I and pharmacokinetic evaluation of All-Trans-Retinoic Acid in pediatric patients with cancer. J of Clin Oncol 1992;10:1666-73.
-
(1992)
J of Clin Oncol
, vol.10
, pp. 1666-1673
-
-
Smith, M.A.1
Adamson, P.C.2
Balis, F.M.3
-
5
-
-
0029553179
-
A phase I study of acivicin in refractory pediatric solid tumors
-
Baruchel S, Bernstein M, Whitehead M, et al. A phase I study of acivicin in refractory pediatric solid tumors. Invest New Drugs 1995;13:211-6.
-
(1995)
Invest New Drugs
, vol.13
, pp. 211-216
-
-
Baruchel, S.1
Bernstein, M.2
Whitehead, M.3
-
6
-
-
0019857236
-
Phase I study on 5-AZA-deoxycytidine in children with acute leukemia
-
Rivard GE, Momparler RL, Demers J, et al. Phase I study on 5-AZA-deoxycytidine in children with acute leukemia. Leuk Res 1981;5:453-62.
-
(1981)
Leuk Res
, vol.5
, pp. 453-462
-
-
Rivard, G.E.1
Momparler, R.L.2
Demers, J.3
-
7
-
-
0021346105
-
Phase I study of aziridinyl-benzoquinone (AZQ, NSC 182986) in children with cancer
-
Tan CTC, Hancock CH, Mondora A, et al. Phase I study of aziridinyl-benzoquinone (AZQ, NSC 182986) in children with cancer. Cancer Res 1984;44:831-5.
-
(1984)
Cancer Res
, vol.44
, pp. 831-835
-
-
Tan, C.T.C.1
Hancock, C.H.2
Mondora, A.3
-
8
-
-
0022523336
-
Phase I clinical and pharmacokinetic study of bisantrene in refractory pediatric solid tumors
-
Pratt CB, Sinkule JA, Etcubanas E, et al. Phase I clinical and pharmacokinetic study of bisantrene in refractory pediatric solid tumors. Invest New Drugs 1986;4:149-53.
-
(1986)
Invest New Drugs
, vol.4
, pp. 149-153
-
-
Pratt, C.B.1
Sinkule, J.A.2
Etcubanas, E.3
-
9
-
-
0022493977
-
Phase I study of carboplatin (CBDCA) in children with cancer
-
Bacha DM, Caparros-Sison B, Allen JA, et al. Phase I study of carboplatin (CBDCA) in children with cancer. Cancer Treat Rep 1986;70:865-9.
-
(1986)
Cancer Treat Rep
, vol.70
, pp. 865-869
-
-
Bacha, D.M.1
Caparros-Sison, B.2
Allen, J.A.3
-
10
-
-
0023521414
-
Pediatric phase I trial of carboplatin: A Childrens Cancer Study Group report
-
Gaynon PS, Ettinger LJ, Moel D, et al. Pediatric phase I trial of carboplatin: a Childrens Cancer Study Group report. Cancer Treat Rep 1987;71:1039-42.
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 1039-1042
-
-
Gaynon, P.S.1
Ettinger, L.J.2
Moel, D.3
-
11
-
-
0027200804
-
A phase I study of carboplatin in children with acute leukemia in bone marrow relapse
-
Ettinger LJ, Krailo MD, Gaynon PS, et al. A phase I study of carboplatin in children with acute leukemia in bone marrow relapse. Cancer 1993;72: 917-22.
-
(1993)
Cancer
, vol.72
, pp. 917-922
-
-
Ettinger, L.J.1
Krailo, M.D.2
Gaynon, P.S.3
-
12
-
-
0026100242
-
A phase 1 clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia
-
Santana VM, Mirro, Jr. J, Harwood FC, et al. A phase 1 clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia. J Clin Oncol 1991;9:416-22.
-
(1991)
J Clin Oncol
, vol.9
, pp. 416-422
-
-
Santana, V.M.1
Mirro J., Jr.2
Harwood, F.C.3
-
13
-
-
0018595292
-
Evaluation of cyclocytidine in children with advanced acute leukemia and solid tumors
-
Finklestein JZ, Higgins G, Krivit W, et al. Evaluation of cyclocytidine in children with advanced acute leukemia and solid tumors. Cancer Treat Rep 1979;63:1331-3.
-
(1979)
Cancer Treat Rep
, vol.63
, pp. 1331-1333
-
-
Finklestein, J.Z.1
Higgins, G.2
Krivit, W.3
-
14
-
-
0019467252
-
Phase I study of 2′-deoxycoformycin in acute lymphoblastic leukemia
-
Poplack DG, Sallan SE, Rivera G, et al. Phase I study of 2′-deoxycoformycin in acute lymphoblastic leukemia. Cancer Res 1981;41:3343-6.
-
(1981)
Cancer Res
, vol.41
, pp. 3343-3346
-
-
Poplack, D.G.1
Sallan, S.E.2
Rivera, G.3
-
15
-
-
0024316286
-
Phase I study of 4′-deoxydoxorubicin (esorubicin) in children with malignant solid tumors
-
Pratt CB, Douglass EC, Meyer WH, et al. Phase I study of 4′-deoxydoxorubicin (esorubicin) in children with malignant solid tumors. Invest New Drugs 1989;7:209-11.
-
(1989)
Invest New Drugs
, vol.7
, pp. 209-211
-
-
Pratt, C.B.1
Douglass, E.C.2
Meyer, W.H.3
-
16
-
-
0021827603
-
Phase I evaluation of β-2′-deoxythioguanosine in pediatric patients with leukemia
-
Higgins GR, Jamin DC, Shore NA, et al. Phase I evaluation of β-2′-deoxythioguanosine in pediatric patients with leukemia. Cancer Treat Rep 1985;69:699-701.
-
(1985)
Cancer Treat Rep
, vol.69
, pp. 699-701
-
-
Higgins, G.R.1
Jamin, D.C.2
Shore, N.A.3
-
17
-
-
0021867679
-
Phase 1 clinical evaluation of diaziquone in childhood cancer
-
Ettinger LJ, Siegel SE, Belasco JB, et al. Phase 1 clinical evaluation of diaziquone in childhood cancer. Cancer Treat Rep 1985;69:323-7.
-
(1985)
Cancer Treat Rep
, vol.69
, pp. 323-327
-
-
Ettinger, L.J.1
Siegel, S.E.2
Belasco, J.B.3
-
18
-
-
0025279037
-
Phase I evaluation of diaziquone in childhood cancer
-
Falletta JM, Gushing B, Lauer S, et al. Phase I evaluation of diaziquone in childhood cancer. Invest New Drugs 1990;8:167-70.
-
(1990)
Invest New Drugs
, vol.8
, pp. 167-170
-
-
Falletta, J.M.1
Gushing, B.2
Lauer, S.3
-
19
-
-
0023856453
-
Pharmacokinetic and phase I study of intravenous DON (6-diazo-5-oxo-L-norleucine) in children
-
Sullivan MP, Nelson JA, Feldman S, et al. Pharmacokinetic and phase I study of intravenous DON (6-diazo-5-oxo-L-norleucine) in children. Cancer Chemother Pharmacol 1988;21:78-84.
-
(1988)
Cancer Chemother Pharmacol
, vol.21
, pp. 78-84
-
-
Sullivan, M.P.1
Nelson, J.A.2
Feldman, S.3
-
20
-
-
0028176596
-
Phase I study of oral etoposide in children with refractory solid tumors
-
Mathew P, Ribeiro RC, Sonnichsen D, et al. Phase I study of oral etoposide in children with refractory solid tumors. J Clin Oncol 1994;12:1452-7.
-
(1994)
J Clin Oncol
, vol.12
, pp. 1452-1457
-
-
Mathew, P.1
Ribeiro, R.C.2
Sonnichsen, D.3
-
21
-
-
0027740033
-
A phase I trial of fazarabine in refractory pediatric solid tumors: A Pediatric Oncology Group study
-
Bernstein ML, Whitehead VM, Grier H, et al. A phase I trial of fazarabine in refractory pediatric solid tumors: a Pediatric Oncology Group study. Invest New Drugs 1993;11:309-12.
-
(1993)
Invest New Drugs
, vol.11
, pp. 309-312
-
-
Bernstein, M.L.1
Whitehead, V.M.2
Grier, H.3
-
22
-
-
0024443913
-
Phase I trial and pharmacokinetic evaluation of fazarabine in children
-
Heideman RL, Gillespie A, Ford H, et al. Phase I trial and pharmacokinetic evaluation of fazarabine in children. Cancer Res 1989;49:5213-6.
-
(1989)
Cancer Res
, vol.49
, pp. 5213-5216
-
-
Heideman, R.L.1
Gillespie, A.2
Ford, H.3
-
23
-
-
0025789733
-
Phase I study of flavone acetic acid (NSC 347512, LM975) in patients with pediatric malignant solid tumors
-
Pratt CB, Relling MV, Meyer WH, et al. Phase I study of flavone acetic acid (NSC 347512, LM975) in patients with pediatric malignant solid tumors. Am J Clin Oncol 1991;14:483-6.
-
(1991)
Am J Clin Oncol
, vol.14
, pp. 483-486
-
-
Pratt, C.B.1
Relling, M.V.2
Meyer, W.H.3
-
24
-
-
0025221247
-
Pharmacology of fludarabine phosphate after a phase I/II trial by a loading bolus and continuous infusion in pediatric patients
-
Avramis VI, Champagne J, Sato J, et al. Pharmacology of fludarabine phosphate after a phase I/II trial by a loading bolus and continuous infusion in pediatric patients. Cancer Res 1990;50:7226-31.
-
(1990)
Cancer Res
, vol.50
, pp. 7226-7231
-
-
Avramis, V.I.1
Champagne, J.2
Sato, J.3
-
25
-
-
0025287674
-
Phase I study of a 120-hour continuous intravenous infusion of 5-fluorouracil in pediatric patients with recurrent solid tumors: A Pediatric Oncology Group study
-
Green DM, Krischer JP, Bell B, et al. Phase I study of a 120-hour continuous intravenous infusion of 5-fluorouracil in pediatric patients with recurrent solid tumors: A Pediatric Oncology Group study. Med Pediatr Oncol 1990;18:321-4.
-
(1990)
Med Pediatr Oncol
, vol.18
, pp. 321-324
-
-
Green, D.M.1
Krischer, J.P.2
Bell, B.3
-
26
-
-
0023461335
-
Phase I trial of homoharringtonine in children with refractory leukemia
-
Tan CTC, Luks E, Bacha DM et al. Phase I trial of homoharringtonine in children with refractory leukemia. Cancer Treat Rep 1987;71:1245-8.
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 1245-1248
-
-
Tan, C.T.C.1
Luks, E.2
Bacha, D.M.3
-
27
-
-
0022507449
-
Phase I study of ICRF-187 in pediatric cancer patients and comparison of its pharmacokinetics in children and adults
-
Holcenberg JS, Tutsch KD, Earhart RH, et al. Phase I study of ICRF-187 in pediatric cancer patients and comparison of its pharmacokinetics in children and adults. Cancer Treat Rep 1986;70:703-9.
-
(1986)
Cancer Treat Rep
, vol.70
, pp. 703-709
-
-
Holcenberg, J.S.1
Tutsch, K.D.2
Earhart, R.H.3
-
28
-
-
0023278663
-
Phase I and clinical pharmacological study of 4-demethoxydaunorubicin (idarubicin) in children with advanced cancer
-
Tan CTC, Hancock, Steinherz P, et al. Phase I and clinical pharmacological study of 4-demethoxydaunorubicin (idarubicin) in children with advanced cancer. Cancer Res 1987;47:2990-5.
-
(1987)
Cancer Res
, vol.47
, pp. 2990-2995
-
-
Tan, C.T.C.1
Hancock2
Steinherz, P.3
-
29
-
-
0023750607
-
Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia
-
Pui C-H, de Graaf SSN, Dow LW, et al. Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia. Cancer Res 1988;48:5348-52.
-
(1988)
Cancer Res
, vol.48
, pp. 5348-5352
-
-
Pui, C.-H.1
De Graaf, S.S.N.2
Dow, L.W.3
-
30
-
-
0027180881
-
A phase I study of ifosfamide with mesna given daily for 3 consecutive days to children with malignant solid tumors
-
Pratt CB, Meyer WH, Douglass EC, et al. A phase I study of ifosfamide with mesna given daily for 3 consecutive days to children with malignant solid tumors. Cancer 1993;71:3661-5.
-
(1993)
Cancer
, vol.71
, pp. 3661-3665
-
-
Pratt, C.B.1
Meyer, W.H.2
Douglass, E.C.3
-
31
-
-
0027233725
-
A phase I study of ifosfamidc given on alternate days to treat children with brain tumors
-
Pratt CB, Douglass EC, Kovnar EH, et al. A phase I study of ifosfamidc given on alternate days to treat children with brain tumors. Cancer 1993;71:3666-9.
-
(1993)
Cancer
, vol.71
, pp. 3666-3669
-
-
Pratt, C.B.1
Douglass, E.C.2
Kovnar, E.H.3
-
32
-
-
0025164637
-
Phase I trial of indicine-N-oxide in children with leukemia and solid tumors: A Pediatric Oncology Group study
-
Whitehead VM, Bernstein ML, Vega R, et al. Phase I trial of indicine-N-oxide in children with leukemia and solid tumors: a Pediatric Oncology Group study. Cancer Chemother Pharmacol 1990;26:377-9.
-
(1990)
Cancer Chemother Pharmacol
, vol.26
, pp. 377-379
-
-
Whitehead, V.M.1
Bernstein, M.L.2
Vega, R.3
-
33
-
-
0025897346
-
Recombinant interferon beta: A phase I/II trial in children with recurrent brain tumors
-
Allen J, Packer R, Bleyer A, et al. Recombinant interferon beta: A phase I/II trial in children with recurrent brain tumors. J Clin Oncol 1991;9:783-8.
-
(1991)
J Clin Oncol
, vol.9
, pp. 783-788
-
-
Allen, J.1
Packer, R.2
Bleyer, A.3
-
34
-
-
0026563941
-
Phase I study of recombinant human interferon gamma in children with relapsed acute leukemia
-
Mahmoud HH, Pui C-H, Kennedy W, et al. Phase I study of recombinant human interferon gamma in children with relapsed acute leukemia. Leukemia 1992;6:1181-4.
-
(1992)
Leukemia
, vol.6
, pp. 1181-1184
-
-
Mahmoud, H.H.1
Pui, C.-H.2
Kennedy, W.3
-
36
-
-
0024394993
-
A phase I study of interleukin-2 in children with cancer and evaluation of clinical and immunologic status during therapy: A Pediatric Oncology Group study
-
Nasr S, McKolanis J, Pais R, et al. A phase I study of interleukin-2 in children with cancer and evaluation of clinical and immunologic status during therapy: A Pediatric Oncology Group study. Cancer 1989;64:783-8.
-
(1989)
Cancer
, vol.64
, pp. 783-788
-
-
Nasr, S.1
McKolanis, J.2
Pais, R.3
-
37
-
-
0026736580
-
Phase I study of recombinant human interleukein-2 for pediatric malignancies: Feasibility of outpatient therapy. A Pediatric Oncology Group Study
-
Pais RC, Abdel-Mageed A, Ghim TT, et al. Phase I study of recombinant human interleukein-2 for pediatric malignancies: feasibility of outpatient therapy. A Pediatric Oncology Group Study. J Immunother 1992;12:138-46.
-
(1992)
J Immunother
, vol.12
, pp. 138-146
-
-
Pais, R.C.1
Abdel-Mageed, A.2
Ghim, T.T.3
-
38
-
-
0027093713
-
Phase I/II study of iodine 131 metaiodobenzylguanidine in chemoresistant neuroblastoma: A United Kingdom Children's Cancer Study Group investigation
-
Lashford LS, Lewis IJ, Fielding SK, et al. Phase I/II study of iodine 131 metaiodobenzylguanidine in chemoresistant neuroblastoma: a United Kingdom Children's Cancer Study Group investigation. J Clin Oncol 1992;10:1889-96.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1889-1896
-
-
Lashford, L.S.1
Lewis, I.J.2
Fielding, S.K.3
-
39
-
-
0023130855
-
Phase I study of iproplatin in pediatric patients: A Pediatric Group Study
-
Pratt CB, Kamen BA, Winick N, et al. Phase I study of iproplatin in pediatric patients: a Pediatric Group Study. Cancer Treat Rep 1987;71:87-8.
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 87-88
-
-
Pratt, C.B.1
Kamen, B.A.2
Winick, N.3
-
41
-
-
0021887929
-
Mitoxantrone in refractory acute leukemia in children: A phase I study
-
Starling KA, Mulne AF, Vats TS, et al. Mitoxantrone in refractory acute leukemia in children: a phase I study. Invest New Drugs 1985;3:191-5.
-
(1985)
Invest New Drugs
, vol.3
, pp. 191-195
-
-
Starling, K.A.1
Mulne, A.F.2
Vats, T.S.3
-
42
-
-
0018215462
-
Phase I study of neocarzinostatin in children with cancer
-
Rivera G, Howarth C, Aur RJA, et al. Phase I study of neocarzinostatin in children with cancer. Cancer Treat Rep 1978;62:2105-7.
-
(1978)
Cancer Treat Rep
, vol.62
, pp. 2105-2107
-
-
Rivera, G.1
Howarth, C.2
Aur, R.J.A.3
-
43
-
-
85061023349
-
Phase I trial of N-methylformamide in pediatric patients with refractory leukemia
-
Murphy SB, Mirro J, Pui C-H, et al. Phase I trial of N-methylformamide in pediatric patients with refractory leukemia. Cancer Treat Rep 1987;12:1229-30.
-
(1987)
Cancer Treat Rep
, vol.12
, pp. 1229-1230
-
-
Murphy, S.B.1
Mirro, J.2
Pui, C.-H.3
-
44
-
-
0027332874
-
Phase I trial of paclitaxel in children with refractory solid tumors: A Pediatric Oncology Group study
-
Hurwitz CA, Relling MV, Weitman SD, et al. Phase I trial of paclitaxel in children with refractory solid tumors: A Pediatric Oncology Group study. J Clin Oncol 1993;11:2324-9.
-
(1993)
J Clin Oncol
, vol.11
, pp. 2324-2329
-
-
Hurwitz, C.A.1
Relling, M.V.2
Weitman, S.D.3
-
45
-
-
0026517786
-
Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule
-
Adamson PC, Balis FM, Miser J, et al. Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule. Cancer Res 1992;52:521-4.
-
(1992)
Cancer Res
, vol.52
, pp. 521-524
-
-
Adamson, P.C.1
Balis, F.M.2
Miser, J.3
-
46
-
-
0025337302
-
Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule
-
Adamson PC, Balis FM, Miser J, et al. Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule. Cancer Res 1990;50:4464-7.
-
(1990)
Cancer Res
, vol.50
, pp. 4464-4467
-
-
Adamson, P.C.1
Balis, F.M.2
Miser, J.3
-
47
-
-
0023199546
-
Phase I trial of procarbazine as a 5-day continuous infusion in children with central nervous system tumors
-
Van Eys J, Cangir A, Pack R, et al. Phase I trial of procarbazine as a 5-day continuous infusion in children with central nervous system tumors. Cancer Treat Rep 1987;71:973-4.
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 973-974
-
-
Van Eys, J.1
Cangir, A.2
Pack, R.3
-
48
-
-
0019495535
-
Phase I trial of rubidazone (NSC 164011) in children with cancer
-
Tan CTC, Mitta SK, Steinherz L, et al. Phase I trial of rubidazone (NSC 164011) in children with cancer. Med Ped Oncol 1981;9:347-53.
-
(1981)
Med Ped Oncol
, vol.9
, pp. 347-353
-
-
Tan, C.T.C.1
Mitta, S.K.2
Steinherz, L.3
-
49
-
-
0023881861
-
A pediatric phase I and pharmacokinetic study of spirohydantoin mustard
-
Heideman RL, Kelley JA, Packer RJ, et al. A pediatric phase I and pharmacokinetic study of spirohydantoin mustard. Cancer Res 1988;48:2292-5.
-
(1988)
Cancer Res
, vol.48
, pp. 2292-2295
-
-
Heideman, R.L.1
Kelley, J.A.2
Packer, R.J.3
-
50
-
-
0029101271
-
A phase I study of sulofenur in refractory pediatric malignant solid tumors
-
Pratt CB, Bowman LC, Marina N, et al. A phase I study of sulofenur in refractory pediatric malignant solid tumors. Invest New Drugs 1995;13:63-6.
-
(1995)
Invest New Drugs
, vol.13
, pp. 63-66
-
-
Pratt, C.B.1
Bowman, L.C.2
Marina, N.3
-
51
-
-
0024499359
-
Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: Evidence for dose-dependent plasma clearance of thiotepa
-
Heideman RL, Cole DE, Balis F, et al. Phase I and pharmacokinetic evaluation of thiotepa in the cerebrospinal fluid and plasma of pediatric patients: evidence for dose-dependent plasma clearance of thiotepa. Cancer Res 1989;49:736-41.
-
(1989)
Cancer Res
, vol.49
, pp. 736-741
-
-
Heideman, R.L.1
Cole, D.E.2
Balis, F.3
-
52
-
-
0022403035
-
Pediatric phase I trial and pharmacokinetic study of tiazofurin (NSC 286193)
-
Balis FM, Lange BJ, Packer RJ, et al. Pediatric phase I trial and pharmacokinetic study of tiazofurin (NSC 286193). Cancer Res 1985;45:5169-72.
-
(1985)
Cancer Res
, vol.45
, pp. 5169-5172
-
-
Balis, F.M.1
Lange, B.J.2
Packer, R.J.3
-
53
-
-
0027407637
-
Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion
-
Blaney SM, Balis FM, Cole DE, et al. Pediatric phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion. Cancer Res 1993;53:1032-6.
-
(1993)
Cancer Res
, vol.53
, pp. 1032-1036
-
-
Blaney, S.M.1
Balis, F.M.2
Cole, D.E.3
-
54
-
-
0028357993
-
Phase I study of topotecan for pediatric patients with malignant solid tumors
-
Pratt CB, Stewart C, Santana VM, et al. Phase I study of topotecan for pediatric patients with malignant solid tumors. J Clin Oncol 1994;12:539-43.
-
(1994)
J Clin Oncol
, vol.12
, pp. 539-543
-
-
Pratt, C.B.1
Stewart, C.2
Santana, V.M.3
-
55
-
-
0023200411
-
Pediatric phase I trial and pharmacokinetic study of trimetrexate
-
Balis FM, Patel R, Luks E, et al. Pediatric phase I trial and pharmacokinetic study of trimetrexate. Cancer Res 1987;47:4973-6.
-
(1987)
Cancer Res
, vol.47
, pp. 4973-4976
-
-
Balis, F.M.1
Patel, R.2
Luks, E.3
-
56
-
-
0027461778
-
Phase I trial of trimetrexate in pediatric solid tumors: A Pediatric Oncology Group study
-
Pappo AS, Vats T, Williams TE, et al. Phase I trial of trimetrexate in pediatric solid tumors: A Pediatric Oncology Group study. Med Ped Oncol 1993;21:280-2.
-
(1993)
Med Ped Oncol
, vol.21
, pp. 280-282
-
-
Pappo, A.S.1
Vats, T.2
Williams, T.E.3
-
57
-
-
0027331526
-
Phase I clinical trial of recombinant human tumor necrosis factor in children with refractory solid tumors: A Pediatric Oncology Group study
-
Furman WL, Strother D, McClain K, et al. Phase I clinical trial of recombinant human tumor necrosis factor in children with refractory solid tumors: A Pediatric Oncology Group study. J Clin Oncol 1993;11:2205-10.
-
(1993)
J Clin Oncol
, vol.11
, pp. 2205-2210
-
-
Furman, W.L.1
Strother, D.2
McClain, K.3
-
58
-
-
0019170358
-
Phase I evaluation of vindesine in children: A Southwest Oncology Group Pilot Study
-
Komp D, Vats T, Shepherd DA, et al. Phase I evaluation of vindesine in children: a Southwest Oncology Group Pilot Study. Med Fed Oncol 1980;8:243-50.
-
(1980)
Med Fed Oncol
, vol.8
, pp. 243-250
-
-
Komp, D.1
Vats, T.2
Shepherd, D.A.3
-
59
-
-
0025924266
-
Response rates, duration of response, and dose response effects in phase I studies of antineoplastics
-
Von Hoff DD, Turner J, Response rates, duration of response, and dose response effects in phase I studies of antineoplastics. Invest New Drugs 1991;9:115-22.
-
(1991)
Invest New Drugs
, vol.9
, pp. 115-122
-
-
Von Hoff, D.D.1
Turner, J.2
-
60
-
-
0025353690
-
Responses and toxic deaths in phase I clinical trials
-
Decoster G, Stein G, Holdener EE, Responses and toxic deaths in phase I clinical trials. Ann Oncol 1990;1:175-81.
-
(1990)
Ann Oncol
, vol.1
, pp. 175-181
-
-
Decoster, G.1
Stein, G.2
Holdener, E.E.3
-
61
-
-
0022542911
-
Therapeutic response in phase I trials of antineoplastic agents
-
Estey E, Hoth D, Simon R, et al. Therapeutic response in phase I trials of antineoplastic agents. Cancer Treat Rep 1986;70:1105-15.
-
(1986)
Cancer Treat Rep
, vol.70
, pp. 1105-1115
-
-
Estey, E.1
Hoth, D.2
Simon, R.3
-
62
-
-
0030920199
-
Pediatric phase II cancer chemotherapy trials: A Pediatric Oncology Group study
-
Weitman S, Ochoa S, Sullivan J, et al. Pediatric phase II cancer chemotherapy trials: a Pediatric Oncology Group study. J Pediatr Hematol Oncol 1997;19:187-91.
-
(1997)
J Pediatr Hematol Oncol
, vol.19
, pp. 187-191
-
-
Weitman, S.1
Ochoa, S.2
Sullivan, J.3
-
63
-
-
0027524863
-
Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents
-
Ratain MJ, Mick R, Schilsky R, et al. Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents. J Natl Cancer Inst 1993;85:1637-43.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1637-1643
-
-
Ratain, M.J.1
Mick, R.2
Schilsky, R.3
-
64
-
-
0029793053
-
Workshop on phase I study design
-
Arbuck SG. Workshop on phase I study design. Ann Oncol 1996;7:567-73.
-
(1996)
Ann Oncol
, vol.7
, pp. 567-573
-
-
Arbuck, S.G.1
-
65
-
-
0023757107
-
Clinical trials in pediatric oncology
-
Leventhal BG and Graham ML. Clinical trials in pediatric oncology. Semin Oncol 1988;15:482-7.
-
(1988)
Semin Oncol
, vol.15
, pp. 482-487
-
-
Leventhal, B.G.1
Graham, M.L.2
|