RhoA and MAPK signal transduction pathways regulate NHE1-dependent proximal tubule cell apoptosis after mechanical stretch

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 7, 2014, Pages F881-F889

  Bocanegra, Victoria ^a   Gil Lorenzo, Andrea Fernanda ^a   Cacciamani, Valeria ^b   Benardón, MaríA Eugenia ^b   Costantino, Valeria Victoria ^a   Vallés, Patricia G ^a,b  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b Universidad Nacional de Cuyo Facultad de Ciencias Medicas   (Argentina)

Author keywords

Apoptosis; Mechanical stretch; Mitogen activated protein kinases; Na+ H+ exchanger 1; Proximal tubule cell; RhoA

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN;

APOPTOSIS; ARTICLE; CELL LYSATE; CELL PH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE; IN VITRO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; PH MEASUREMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTON SODIUM EXCHANGE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL LINE; ENZYMOLOGY; MECHANICAL STRESS; METABOLISM; PATHOPHYSIOLOGY; URETER OBSTRUCTION;

APOPTOSIS; CELL LINE; HUMANS; KIDNEY TUBULES, PROXIMAL; MAP KINASE SIGNALING SYSTEM; RECEPTOR CROSS-TALK; RHOA GTP-BINDING PROTEIN; SODIUM-HYDROGEN ANTIPORTER; STRESS, MECHANICAL; URETERAL OBSTRUCTION;

EID: 84907495270     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00232.2014     Document Type: Article

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