Apoptosis induction is associated with decreased NHE1 expression in neonatal unilateral ureteric obstruction

BJU International

Volumn 100, Issue 1, 2007, Pages 191-198

  Manucha, Walter ^a,b   Carrizo, Liliana ^a   Ruete, Celeste ^b   Vallés, Patricia G ^a,b  

^a Universidad Nacional de Cuyo Facultad de Ciencias Medicas   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Apoptosis; Caspase 3 expression; Neonatal unilateral ureteric obstruction; NHE1 expression

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; CASPASE 3; MESSENGER RNA; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; SODIUM PROTON EXCHANGE PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; GENE EXPRESSION; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MITOCHONDRION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STANDARD; URETER OBSTRUCTION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CATION TRANSPORT PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER; URETERAL OBSTRUCTION;

EID: 34249944402     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2007.06840.x     Document Type: Article

References (29)

1. Warady BA, Hebert D, Sullivan EK, Alexander SR, Tejani A. Renal transplantation, chronic dialysis, and chronic renal insufficiency in children and adolescents. The 1995 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Nephrol 1997 11 : 49 64
2. Chevalier RL. Effects of ureteral obstruction on renal growth. Semin Nephrol 1995 15 : 353 60
3. Gobe GC, Axelsen RA. Genesis of renal tubular atrophy in experimental hydronephrosis in the rat. Lab Invest 1987 56 : 273 81
4. Chevalier RL, Chung KH, Smith CD, Ficenec M, Gomez RA. Renal apoptosis and clusterin following ureteral obstruction: the role of maturation. J Urol 1996 156 : 1474 9
5. Chevalier RL, Kim A, Thornill BA, Wolstenholme JT. Recovery following relief of unilateral ureteral obstruction in the neonatal rat. Kidney Int 1999 55 : 793 807
6. Truong LD, Sheikh-Hamad D, Chakaborty S, Suki WN. Cell apoptosis and proliferation in obstructive uropathy. Semin Nephrol 1998 18 : 641 51
7. Miyajima A, Chen J, Lawrence C et al. Antibody to transforming growth factor-β amilorates apoptosis in unilateral ureteral obstruction. Kidney Int 2000 58 : 2301 3
8. Power RE, Doyle BT, Higgins D, Brady HR, Fitzpatrick JM, Watson RW. Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent. J Urol 2004 171 : 457 61
9. Cachat F, Lange-Sperandio B, Chang AY et al. Ureteral obstruction in neonatal mice elicits segment-specific tubular cell responses leading to nephron loss. Kidney Int 2003 63 : 564 75
10. Gottlieb RA, Nordberg J, Skowronski E, Babior BM. Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification. Proc Natl Acad Sci USA 1996 93 : 654 8
11. Lang F, Busch GL, Ritter M et al. Functional significance of cell volume regulatory mechanisms. Physiol Rev 1998 78 : 247 306
12. Orlowski J, Grinstein S. Na+/H+ exchangers of mammalian cells. J Biol Chem 1997 272 : 22373 6
13. Moolenaar WH, Tsien RY, van der Saag PT, de Laat SW. Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts. Nature 1983 304 : 645 8
14. Denker SP, Huang DC, Orlowski J, Furthmayr H, Barber DL. Direct binding of the Na-H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H+ translocation. Mol Cell 2000 6 : 1425 36
15. Morrissey J, Hruska K, Guo G, Wang S, Chen Q, Klahr S. Bone morphometric protein-7 improves renal fibrosis and accelerates the return of renal function. J Am Soc Nephrol 2002 13 : S14 21
16. Berrebi-Bertrand I, Maixent JM. Immunodetection and enzymatic characterization of the α3-isoform of Na,K-ATPase in dog heart. FEBS Lett 1994 348 : 55 60
17. Counillon L, Scholz W, Lang HJ, Pouyssegur J. Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties. Mol Pharmacol 1993 44 : 1041 5
18. Cortell S, Gennari FJ, Davidman M, Bossert WH, Schwartz WB. A definition of proximal and distal tubular compliance. Practical and theoretical implications. J Clin Invest 1973 52 : 2330 9
19. Bortner CD, Cidlowski JA. Apoptotic volume decrease and the incredible shrinking cell. Cell Death Differ 2002 9 : 1307 10
20. Collins JF, Xu H, Kiela PR, Zeng J, Ghishan FK. Ontogeny of basolateral membrane sodium-hydrogen exchange (NHE) activity and mRNA expression of NHE-1 and NH-4 in rat kidney and jejunum. Biochim Biophys Acta 1998 1369 : 247 58
21. Thomsen K, Jonassen TEN, Christensen S, Shirley DG. Amiloride inhibits proximal tubular reabsorption in conscious euvolemic rats. Eur J Pharmacol 2002 437 : 85 90
22. Truong LD, Choi YJ, Tsao CC et al. Renal cell apoptosis in chronic obstructive uropathy: the roles of caspases. Kidney Int 2001 60 : 924 34
23. Khaled AR, Kim K, Hofmeister R, Muegge K, Durum SK. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. Proc Natl Acad Sci USA 1999 96 : 14476 81
24. Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL. Regulation of intracellular pH mediates Bax activation in HeLa cells treated with Staurosporine or tumor necrosis factor-α. J Biol Chem 2002 277 : 49569 76
25. Chevalier RL, Smith CD, Wolstenholme J, Krajewski S, Reed JC. Chronic ureteral obstruction in the rat supresses renal tubular Bcl-2 and stimulates apoptosis. Exp Nephrol 2000 8 : 115 22
26. Wu K, Khan S, Lakhe-Reddy S et al. Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger. Am J Physiol Renal Physiol 2003 284 : F829 39
27. Okada Y, Maeno E, Shimizu T, Dezaki K, Wang J, Morishima S. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol 2001 532 : 3 16
28. Soleimani M, Watts BA 3rd, Singh G, Good DW. Effect of long-term hyperosmolality on the Na+/H+ exchanger isoform NHE-3 in LLC-PK1 cells. Kidney Int 1998 53 : 423 31
29. Wu KL, Khan S, Lakhe-Reddy S et al. The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. J Biol Chem 2004 279 : 26280 6