Carbonic anhydrase 2 deficiency leads to increased pyelonephritis susceptibility

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 7, 2014, Pages F869-F880

  Hains, David S ^a   Chen, Xi ^a,b   Saxena, Vijay ^b   Barr Beare, Evan ^b   Flemming, Weisi ^b   Easterling, Robert ^b   Becknell, Brian ^b,c,d   Schwartz, George J ^e   Schwaderer, Andrew L ^b,c,d  

^a Lebonheur Children's Hospital   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Acid base; Inflammation; Intercalated cells; Urinary tract infection

Indexed keywords

BICARBONATE; CARBONATE DEHYDRATASE II; INTERFERON REGULATORY FACTOR 5; MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; POTASSIUM; CARBONATE DEHYDRATASE; LIPOCALIN;

ACID BASE BALANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERIAL LOAD; BICARBONATE BLOOD LEVEL; BLOOD PH; CONTROLLED STUDY; EMBRYO; ENZYME DEFICIENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL NEPHRITIS; FEMALE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; IMMUNOREACTIVITY; INFECTION SENSITIVITY; INNATE IMMUNITY; INOCULATION; LEUKOCYTE DIFFERENTIAL COUNT; METABOLIC ACIDOSIS; MOUSE; NONHUMAN; PHENOTYPE; POTASSIUM BLOOD LEVEL; PROTEIN EXPRESSION; PYELONEPHRITIS; URINE ACIDIFICATION; URINE PH; UROPATHOGENIC ESCHERICHIA COLI; WILD TYPE; ALBERS SCHOENBERG DISEASE; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DEFICIENCY; IMMUNOLOGY; KIDNEY; KIDNEY TUBULE ACIDOSIS; METABOLISM; MICROBIOLOGY; PH; POLYMERASE CHAIN REACTION; UREA CYCLE DISORDER; URINE;

ACIDOSIS, RENAL TUBULAR; ANIMALS; BICARBONATES; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HYDROGEN-ION CONCENTRATION; IMMUNITY, INNATE; KIDNEY; LIPOCALINS; MICE, INBRED C57BL; OSTEOPETROSIS; PHENOTYPE; POLYMERASE CHAIN REACTION; PYELONEPHRITIS; UREA CYCLE DISORDERS, INBORN; URINE;

EID: 84907486719     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00344.2014     Document Type: Article

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