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Volumn 9, Issue 10, 2014, Pages

Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 84907481710     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108481     Document Type: Article
Times cited : (43)

References (56)
  • 2
    • 0034681976 scopus 로고    scopus 로고
    • Surveillance for outbreaks of respiratory tract infections in nursing homes
    • Loeb M, McGeer A, McArthur M, Peeling RW, Petric M, et al. (2000) Surveillance for outbreaks of respiratory tract infections in nursing homes. CMAJ 162:1133-1137.
    • (2000) CMAJ , vol.162 , pp. 1133-1137
    • Loeb, M.1    McGeer, A.2    McArthur, M.3    Peeling, R.W.4    Petric, M.5
  • 4
    • 21844465943 scopus 로고    scopus 로고
    • Rhinovirus outbreak in a long-term care facility for elderly persons associated with unusually high mortality
    • Louie J, Yagi S, Nelson F, Kiang D, Glaser C, et al. (2005) Rhinovirus outbreak in a long-term care facility for elderly persons associated with unusually high mortality. Clin Infect Dis 41:262-265.
    • (2005) Clin Infect Dis , vol.41 , pp. 262-265
    • Louie, J.1    Yagi, S.2    Nelson, F.3    Kiang, D.4    Glaser, C.5
  • 5
    • 33645077914 scopus 로고    scopus 로고
    • Two outbreaks of severe respiratory disease in nursing homes associated with rhinovirus
    • Hicks L, Shepard C, Britz P, Erdman D, Fischer M, et al. (2006) Two outbreaks of severe respiratory disease in nursing homes associated with rhinovirus. J Am Geriatr Soc 54:284-289.
    • (2006) J Am Geriatr Soc , vol.54 , pp. 284-289
    • Hicks, L.1    Shepard, C.2    Britz, P.3    Erdman, D.4    Fischer, M.5
  • 6
    • 0031011376 scopus 로고    scopus 로고
    • The "common cold" in frail older person: Impact of rhinovirus and coronavirus in a senior daycare center
    • Falsey A, McCann R, Hall W, Criddle M, Formica M, et al. (1997) The "common cold" in frail older person: impact of rhinovirus and coronavirus in a senior daycare center. J Am Geriatr Soc 45:706-711.
    • (1997) J Am Geriatr Soc , vol.45 , pp. 706-711
    • Falsey, A.1    McCann, R.2    Hall, W.3    Criddle, M.4    Formica, M.5
  • 7
    • 34247219202 scopus 로고    scopus 로고
    • An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility
    • Boivin G, De Serres G, Hamelin M, Côté S, Argouin M, et al. (2007) An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility. Clin Infect Dis 44:1152-1158.
    • (2007) Clin Infect Dis , vol.44 , pp. 1152-1158
    • Boivin, G.1    De Serres, G.2    Hamelin, M.3    Côté, S.4    Argouin, M.5
  • 8
    • 51049085552 scopus 로고    scopus 로고
    • SHEA/APIC Guideline: Infection prevention and control in the long-term care facility; Society for Healthcare Epidemiology of America (SHEA); Association for Professionals in Infection Control and Epidemiology (APIC)
    • Smith P, Bennett G, Bradley S, Drinka P, Lautenbach E, et al. (2008) SHEA/APIC Guideline: Infection prevention and control in the long-term care facility; Society for Healthcare Epidemiology of America (SHEA); Association for Professionals in Infection Control and Epidemiology (APIC). Am J Infect Control 36:504-535.
    • (2008) Am J Infect Control , vol.36 , pp. 504-535
    • Smith, P.1    Bennett, G.2    Bradley, S.3    Drinka, P.4    Lautenbach, E.5
  • 9
    • 58749114378 scopus 로고    scopus 로고
    • Immunosenescence and vaccination in nursing home residents
    • Fulop T, Pawelec G, Castle S, Loeb M (2009) Immunosenescence and vaccination in nursing home residents. Clin Infect Dis 48:443-448.
    • (2009) Clin Infect Dis , vol.48 , pp. 443-448
    • Fulop, T.1    Pawelec, G.2    Castle, S.3    Loeb, M.4
  • 11
    • 32244433673 scopus 로고    scopus 로고
    • Accumulation of memory T cells from childhood to old age: Central and effector memory cells in CD4+ versus effector memory and terminally differentiated memory cells in CD8+ compartment
    • Saule P, Trauet J, Dutriez V, Lekeux V, Dessaint J, et al. (2006) Accumulation of memory T cells from childhood to old age: central and effector memory cells in CD4+ versus effector memory and terminally differentiated memory cells in CD8+ compartment. Mech Ageing Dev 127:274-281.
    • (2006) Mech Ageing Dev , vol.127 , pp. 274-281
    • Saule, P.1    Trauet, J.2    Dutriez, V.3    Lekeux, V.4    Dessaint, J.5
  • 13
    • 0028043586 scopus 로고
    • Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenecence
    • Effros R, Boucher N, Porter V, Zhu X, Spaulding C, et al. (1994) Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenecence. Exp Gerontol 29:601-609.
    • (1994) Exp Gerontol , vol.29 , pp. 601-609
    • Effros, R.1    Boucher, N.2    Porter, V.3    Zhu, X.4    Spaulding, C.5
  • 15
    • 0037012021 scopus 로고    scopus 로고
    • Expansion of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: The Swedish NONA immune study
    • Wikby A, Johansson B, Olsson J, Löfgren S, Nilsson B, et al. (2002) Expansion of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Exp Gerontol 37:445-453.
    • (2002) Exp Gerontol , vol.37 , pp. 445-453
    • Wikby, A.1    Johansson, B.2    Olsson, J.3    Löfgren, S.4    Nilsson, B.5
  • 16
    • 0032957642 scopus 로고    scopus 로고
    • Role of cytomegalovirus in the T-cell changes seen in elderly individuals
    • Looney R, Falsey A, Campbell D, Torres A, Kolassa J, et al. (1999) Role of cytomegalovirus in the T-cell changes seen in elderly individuals. Clin Immunol 90:213-219.
    • (1999) Clin Immunol , vol.90 , pp. 213-219
    • Looney, R.1    Falsey, A.2    Campbell, D.3    Torres, A.4    Kolassa, J.5
  • 17
    • 24044463890 scopus 로고    scopus 로고
    • Dysregulation of T-cell function in the elderly: Scientific basis and clinical implications
    • Fulop T, Larbi A, Wikby A, Mocchegiani E, Hirokawa K, et al. (2005) Dysregulation of T-cell function in the elderly: scientific basis and clinical implications. Drugs Aging 22:589-603.
    • (2005) Drugs Aging , vol.22 , pp. 589-603
    • Fulop, T.1    Larbi, A.2    Wikby, A.3    Mocchegiani, E.4    Hirokawa, K.5
  • 18
    • 0035202615 scopus 로고    scopus 로고
    • Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
    • Goronzy J, Fulbright J, Crowson C, Poland G, O'Fallon W, et al. (2001) Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. J Virol 75:12182-12187.
    • (2001) J Virol , vol.75 , pp. 12182-12187
    • Goronzy, J.1    Fulbright, J.2    Crowson, C.3    Poland, G.4    O'Fallon, W.5
  • 19
    • 0036604275 scopus 로고    scopus 로고
    • Lack of antibody production following immunization in old age: Association with CD8+ CD28-T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
    • Saurwein-Teissl M, Lung T, Marx F, Gschösser C, Asch E, et al. (2002) Lack of antibody production following immunization in old age: association with CD8+ CD28-T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J Immunol 168:5893-5899.
    • (2002) J Immunol , vol.168 , pp. 5893-5899
    • Saurwein-Teissl, M.1    Lung, T.2    Marx, F.3    Gschösser, C.4    Asch, E.5
  • 20
    • 0242317690 scopus 로고    scopus 로고
    • Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination - An impact of immunosenescence
    • Trzonkowski P, Mysliwska J, Szmit E, Wieckiewicz J, Lukaszuk K, et al. (2003) Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination - an impact of immunosenescence. Vaccine 21:3826-3836.
    • (2003) Vaccine , vol.21 , pp. 3826-3836
    • Trzonkowski, P.1    Mysliwska, J.2    Szmit, E.3    Wieckiewicz, J.4    Lukaszuk, K.5
  • 21
    • 77957744665 scopus 로고    scopus 로고
    • An association between immunosenescence and CD4+CD25+ regulatory T-cells: A systematic review
    • Wang L, Xie Y, Zhu L, Chang T, Mao Y, et al. (2010) An association between immunosenescence and CD4+CD25+ regulatory T-cells: a systematic review. Biomed Environ Sci 23:327-332.
    • (2010) Biomed Environ Sci , vol.23 , pp. 327-332
    • Wang, L.1    Xie, Y.2    Zhu, L.3    Chang, T.4    Mao, Y.5
  • 22
    • 84859316999 scopus 로고    scopus 로고
    • Foxp3+ regulatory T-cells, immune stimulation and host defence against infection
    • Rowe J, Ertelt J, Way S (2012) Foxp3+ regulatory T-cells, immune stimulation and host defence against infection. Immunology 136:1-10.
    • (2012) Immunology , vol.136 , pp. 1-10
    • Rowe, J.1    Ertelt, J.2    Way, S.3
  • 24
    • 84907567187 scopus 로고    scopus 로고
    • Statement on seasonal trivalent inactivated influenza vaccine for 2009-2010
    • Langley J, Warshawsky B, Ismail S, Crowcroft N, Hanrahan A, et al. (2009) Statement on seasonal trivalent inactivated influenza vaccine for 2009-2010. CCDR 35: ACS-6.
    • (2009) CCDR , vol.35 , pp. ACS6
    • Langley, J.1    Warshawsky, B.2    Ismail, S.3    Crowcroft, N.4    Hanrahan, A.5
  • 25
    • 84907567187 scopus 로고    scopus 로고
    • Statement on seasonal trivalent inactivated influenza vaccine for 2010-2011
    • Langley J, Warshawsky B, Ismail S, Crowcroft N, Hanrahan A, et al. (2010) Statement on seasonal trivalent inactivated influenza vaccine for 2010-2011. CCDR 36: ACS-6.
    • (2010) CCDR , vol.36 , pp. ACS6
    • Langley, J.1    Warshawsky, B.2    Ismail, S.3    Crowcroft, N.4    Hanrahan, A.5
  • 26
    • 84907481510 scopus 로고    scopus 로고
    • Statement on seasonal trivalent inactivated influenza vaccine for 2011-2012
    • Langley J, Warshawsky B, Cooper C, Crowcroft N, Hanrahan A, et al. (2011) Statement on seasonal trivalent inactivated influenza vaccine for 2011-2012. CCDR 37: ACS-5.
    • (2011) CCDR , vol.37 , pp. ACS5
    • Langley, J.1    Warshawsky, B.2    Cooper, C.3    Crowcroft, N.4    Hanrahan, A.5
  • 27
    • 30844465227 scopus 로고    scopus 로고
    • Maximizing the retention of antigen specific lymphocyte function after cryopreservation
    • Disis M, dela Rosa C, Goodell V, Kuan L, Chang J, et al. (2006) Maximizing the retention of antigen specific lymphocyte function after cryopreservation. J Immunol 308:13-18.
    • (2006) J Immunol , vol.308 , pp. 13-18
    • Disis, M.1    Dela Rosa, C.2    Goodell, V.3    Kuan, L.4    Chang, J.5
  • 28
    • 84872040653 scopus 로고    scopus 로고
    • The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age
    • Lelic A, Verschoor C, Ventresca M, Parsons R, Evelegh C, et al. (2012) The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age. PLoS Pathog 8:e1003076.
    • (2012) PLoS Pathog , vol.8 , pp. e1003076
    • Lelic, A.1    Verschoor, C.2    Ventresca, M.3    Parsons, R.4    Evelegh, C.5
  • 29
    • 84875658458 scopus 로고    scopus 로고
    • Blood CD33 (+) HLA-DR (-) myeloid-derived suppressor cells are increased with age and a history of cancer
    • Verschoor C, Johnstone J, Millar J, Dorrington M, Habibagahi M, et al. (2013) Blood CD33 (+) HLA-DR (-) myeloid-derived suppressor cells are increased with age and a history of cancer. J Leukoc Biol 93:633-637.
    • (2013) J Leukoc Biol , vol.93 , pp. 633-637
    • Verschoor, C.1    Johnstone, J.2    Millar, J.3    Dorrington, M.4    Habibagahi, M.5
  • 31
    • 78650635637 scopus 로고    scopus 로고
    • Comparison of imputation methods for handling missing covariate data when fitting a Cox proportional hazards model: A resampling study
    • Marshall A, Altman D, Holder R (2010) Comparison of imputation methods for handling missing covariate data when fitting a Cox proportional hazards model: a resampling study. BMC Med Res Methodol 31:112.
    • (2010) BMC Med Res Methodol , vol.31 , pp. 112
    • Marshall, A.1    Altman, D.2    Holder, R.3
  • 33
    • 79953752268 scopus 로고
    • Regression-analysis of multivariate incomplete failure time data by modeling marginal distributions
    • Wei L, Lin D, Weissfeld L (1989) Regression-analysis of multivariate incomplete failure time data by modeling marginal distributions. J Am Stat Assoc 84:1065-1073.
    • (1989) J Am Stat Assoc , vol.84 , pp. 1065-1073
    • Wei, L.1    Lin, D.2    Weissfeld, L.3
  • 34
    • 84863304598 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria
    • R Core Team (2013) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. Available: http://www. R-project.org/.
    • (2013) R: A Language and Environment for Statistical Computing
  • 35
    • 42549101917 scopus 로고    scopus 로고
    • The role of regulatory T-cells in chronic and acute viral infections
    • Keynan Y, Card C, McLaren P, Dawood M, Kasper K, et al. (2008) The role of regulatory T-cells in chronic and acute viral infections. Clin Infect Dis 46:1046-1052.
    • (2008) Clin Infect Dis , vol.46 , pp. 1046-1052
    • Keynan, Y.1    Card, C.2    McLaren, P.3    Dawood, M.4    Kasper, K.5
  • 36
    • 49649117750 scopus 로고    scopus 로고
    • Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation
    • Lages C, Suffia I, Velilla P, Huang B, Warshaw G, et al. (2008) Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol 181:1835-1848.
    • (2008) J Immunol , vol.181 , pp. 1835-1848
    • Lages, C.1    Suffia, I.2    Velilla, P.3    Huang, B.4    Warshaw, G.5
  • 37
    • 84857832014 scopus 로고    scopus 로고
    • Influenza A virus infection results in a robust, antigen-responsive, and widely disseminated Fox3+ regulatory T cell response
    • Betts R, Prabhu N, Ho A, Lew F, Hutchinson P, et al. (2012) Influenza A virus infection results in a robust, antigen-responsive, and widely disseminated Fox3+ regulatory T cell response. J Virol 86:2817-2825.
    • (2012) J Virol , vol.86 , pp. 2817-2825
    • Betts, R.1    Prabhu, N.2    Ho, A.3    Lew, F.4    Hutchinson, P.5
  • 38
    • 77956913784 scopus 로고    scopus 로고
    • Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection
    • Fulton R, Meyerholz D, Varga S (2010) Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J Immunol 185:2382-2392.
    • (2010) J Immunol , vol.185 , pp. 2382-2392
    • Fulton, R.1    Meyerholz, D.2    Varga, S.3
  • 39
    • 79955780015 scopus 로고    scopus 로고
    • Expansion of regulatory T cells in aged mice following influenza infection
    • Williams-Bey Y, Jiang J, Murasko D (2011) Expansion of regulatory T cells in aged mice following influenza infection. Mech Ageing Dev 132:163-170.
    • (2011) Mech Ageing Dev , vol.132 , pp. 163-170
    • Williams-Bey, Y.1    Jiang, J.2    Murasko, D.3
  • 42
    • 79960631102 scopus 로고    scopus 로고
    • Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities
    • den Elzen W, Vossen A, Cools H, Westendorp R, Kroes A, et al. (2011) Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities. Vaccine 29:4869-4874.
    • (2011) Vaccine , vol.29 , pp. 4869-4874
    • Den Elzen, W.1    Vossen, A.2    Cools, H.3    Westendorp, R.4    Kroes, A.5
  • 43
    • 84871935156 scopus 로고    scopus 로고
    • Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination
    • Derhovanessian E, Theeten H, Hahnel K, Van Damme P, Cools N, et al. (2013) Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination. Vaccine 31:685-690.
    • (2013) Vaccine , vol.31 , pp. 685-690
    • Derhovanessian, E.1    Theeten, H.2    Hahnel, K.3    Van Damme, P.4    Cools, N.5
  • 44
    • 84862776821 scopus 로고    scopus 로고
    • The unmet need in the elderly: How immunosenescence, CMV infection, comorbidities and frailty are a challenge for the development of more effective influenza vaccines
    • McElhaney J, Zhou X, Talbot H, Soethout E, Bleackley R, et al. (2012) The unmet need in the elderly: How immunosenescence, CMV infection, comorbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine 30:2060-2067.
    • (2012) Vaccine , vol.30 , pp. 2060-2067
    • McElhaney, J.1    Zhou, X.2    Talbot, H.3    Soethout, E.4    Bleackley, R.5
  • 45
    • 82555175345 scopus 로고    scopus 로고
    • Tregs and infections: On the potential value of modifying their function
    • Sehrawat S, Rouse B (2011) Tregs and infections: on the potential value of modifying their function. J Leukoc Biol 90:1079-1087.
    • (2011) J Leukoc Biol , vol.90 , pp. 1079-1087
    • Sehrawat, S.1    Rouse, B.2
  • 47
    • 84887003703 scopus 로고    scopus 로고
    • Understanding the burden of influenza infection among adults in Canadian hospitals: A comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons
    • Mitchell R, Taylor G, McGeer A, Frenette C, Suh K, et al. (2013) Understanding the burden of influenza infection among adults in Canadian hospitals: a comparison of the 2009-2010 pandemic season with the prepandemic and postpandemic seasons. Am J Infect Control 41:1032-1037.
    • (2013) Am J Infect Control , vol.41 , pp. 1032-1037
    • Mitchell, R.1    Taylor, G.2    McGeer, A.3    Frenette, C.4    Suh, K.5
  • 48
    • 33645815277 scopus 로고    scopus 로고
    • Evidence of bias in estimates of influenza vaccine effectiveness in seniors
    • Jackson L, Jackson M, Nelson J, Neuzil K, Weiss N (2006) Evidence of bias in estimates of influenza vaccine effectiveness in seniors. Int J Epidemiol 35:337-344.
    • (2006) Int J Epidemiol , vol.35 , pp. 337-344
    • Jackson, L.1    Jackson, M.2    Nelson, J.3    Neuzil, K.4    Weiss, N.5
  • 49
    • 33645829057 scopus 로고    scopus 로고
    • Functional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniors
    • Jackson L, Nelson J, Benson P, Neuzil K, Reid R, et al. (2006) Functional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniors. Int J Epidemiol 35:345-352.
    • (2006) Int J Epidemiol , vol.35 , pp. 345-352
    • Jackson, L.1    Nelson, J.2    Benson, P.3    Neuzil, K.4    Reid, R.5
  • 50
    • 84857464997 scopus 로고    scopus 로고
    • Against quantiles: Categorization of continuous variables in epidemiologic research, and its discontents
    • Bennette C, Vickers A (2012) Against quantiles: categorization of continuous variables in epidemiologic research, and its discontents. BMC Med Res Methodol 12:21.
    • (2012) BMC Med Res Methodol , vol.12 , pp. 21
    • Bennette, C.1    Vickers, A.2
  • 51
    • 0141992828 scopus 로고    scopus 로고
    • Lymphocyte count and mortality risk in older persons. The Leiden 85-plus study
    • Izaks G, Remarque E, Becker S, Westendorp R (2003) Lymphocyte count and mortality risk in older persons. The Leiden 85-plus study. J Am Geriatr Soc 51:1461-1465.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 1461-1465
    • Izaks, G.1    Remarque, E.2    Becker, S.3    Westendorp, R.4
  • 52
    • 67650594923 scopus 로고    scopus 로고
    • Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: Results from the Women's Health and Aging Studies I
    • Leng S, Xue Q, Tian J, Huang Y, Yeh S, et al. (2009) Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies I. Experimental Gerontol 44:511-516.
    • (2009) Experimental Gerontol , vol.44 , pp. 511-516
    • Leng, S.1    Xue, Q.2    Tian, J.3    Huang, Y.4    Yeh, S.5
  • 53
    • 84863092748 scopus 로고    scopus 로고
    • Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ study
    • Collerton J, Martin-Ruiz C, Davies K, Hilkens C, Isaacs J, et al. (2012) Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ study. Mech Ageing Dev 133:456-466.
    • (2012) Mech Ageing Dev , vol.133 , pp. 456-466
    • Collerton, J.1    Martin-Ruiz, C.2    Davies, K.3    Hilkens, C.4    Isaacs, J.5
  • 54
    • 77952409018 scopus 로고    scopus 로고
    • Cytomegalovirus infection and the risk of mortality and frailty in older women: A prospective observational cohort study
    • Wang G, Kao W, Murakami P, Xue Q, Chiou R, et al. (2010) Cytomegalovirus infection and the risk of mortality and frailty in older women: a prospective observational cohort study. Am J Epidemiol 171:1144-1152.
    • (2010) Am J Epidemiol , vol.171 , pp. 1144-1152
    • Wang, G.1    Kao, W.2    Murakami, P.3    Xue, Q.4    Chiou, R.5
  • 55
    • 84055175593 scopus 로고    scopus 로고
    • Associations between cytomegalovirus infection and functional impairment and frailty in the BEFRAIL cohort
    • Mathei C, Vaes B, Wallemacq P, Degryse J (2011) Associations between cytomegalovirus infection and functional impairment and frailty in the BEFRAIL cohort. J Am Geriatr Soc 59:2201-2208.
    • (2011) J Am Geriatr Soc , vol.59 , pp. 2201-2208
    • Mathei, C.1    Vaes, B.2    Wallemacq, P.3    Degryse, J.4
  • 56
    • 77950438899 scopus 로고    scopus 로고
    • Competing risk of death: An important consideration in studies of older adults
    • Berry S, Ngo L, Samelson E, Kiel D (2010) Competing risk of death: an important consideration in studies of older adults. J Am Geriatr Soc 58:783-787.
    • (2010) J Am Geriatr Soc , vol.58 , pp. 783-787
    • Berry, S.1    Ngo, L.2    Samelson, E.3    Kiel, D.4


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