Against quantiles: Categorization of continuous variables in epidemiologic research, and its discontents

BMC Medical Research Methodology

Volumn 12, Issue , 2012, Pages

  Bennette, Caroline ^a   Vickers, Andrew ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; EPIDEMIOLOGY; HUMAN; MASS COMMUNICATION; PATIENT SELECTION; RISK FACTOR; STATISTICAL MODEL;

BIAS (EPIDEMIOLOGY); DIFFUSION OF INNOVATION; EPIDEMIOLOGIC RESEARCH DESIGN; HUMANS; MODELS, STATISTICAL; PATIENT SELECTION; RISK FACTORS; SAMPLING STUDIES;

EID: 84857464997     PISSN: None     EISSN: 14712288     Source Type: Journal    
DOI: 10.1186/1471-2288-12-21     Document Type: Article

References (20)

1. Smoking and carcinoma of the lung; preliminary report. Doll R, Hill AB, Br Med J 1950 2 4682 739 748 10.1136/bmj.2.4682.739 14772469
2. Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP Diet and Health Study cohort. Thiebaut AC, Kipnis V, Chang SC, Subar AF, Thompson FE, Rosenberg PS, Hollenbeck AR, Leitzmann M, Schatzkin A, J Natl Cancer Inst 2007 99 6 451 462 10.1093/jnci/djk094 17374835 (Pubitemid 47073568)
3. Relationship between annual volume of patients treated by admitting physician and mortality after acute myocardial infarction. Tu JV, Austin PC, Chan BT, JAMA 2001 285 24 3116 3122 10.1001/jama.285.24.3116 11427140 (Pubitemid 32578208)
4. Rothman K, Greenland S, Lash T, Modern Epidemiology Lippincott Williams & Wilkins 2008 3
5. Avoiding power loss associated with categorization and ordinal scores in dose-response and trend analysis. Greenland S, Epidemiology 1995 6 4 450 454 10.1097/00001648-199507000-00025 7548361
6. Height and Alzheimer's disease: findings from a case-control study. Petot GJ, Vega U, Traore F, Fritsch T, Debanne SM, Friedland RP, Lerner AJ, J Alzheimers Dis 2007 11 3 337 341 17851184 (Pubitemid 47094032)
7. Serum lipids and endometrial cancer risk: results from the HUNT-II study. Lindemann K, Vatten LJ, Ellstrom-Engh M, Eskild A, Int J Cancer 2009 124 12 2938 2941 10.1002/ijc.24285 19267407
8. Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokers. Michaud DS, Wright ME, Cantor KP, Taylor PR, Virtamo J, Albanes D, Am J Epidemiol 2004 160 9 853 859 10.1093/aje/kwh295 15496537 (Pubitemid 39434769)
9. Influence of hospital procedure volume on outcomes following surgery for colon cancer. Schrag D, Cramer LD, Bach PB, Cohen AM, Warren JL, Begg CB, JAMA 2000 284 23 3028 3035 10.1001/jama.284.23.3028 11122590 (Pubitemid 32014740)
10. Influence of hospital characteristics on operative death and survival of patients after major cancer surgery in Ontario. Simunovic M, Rempel E, Theriault ME, Coates A, Whelan T, Holowaty E, Langer B, Levine M, Can J Surg 2006 49 4 251 258 16948883 (Pubitemid 44432802)
11. Dose-response and trend analysis in epidemiology: alternatives to categorical analysis. Greenland S, Epidemiology 1995 6 4 356 365 10.1097/00001648-199507000-00005 7548341
12. A strategy for modelling the effect of a continuous covariate in medicine and epidemiology. Royston P, Stat Med 2000 19 14 1831 1847 10.1002/1097- 0258(20000730)19:14<1831::AID-SIM502>3.0.CO;2-1 10867674 (Pubitemid 30448192)
13. The surgical learning curve for prostate cancer control after radical prostatectomy. Vickers AJ, Bianco FJ, Serio AM, Eastham JA, Schrag D, Klein EA, Reuther AM, Kattan MW, Pontes JE, Scardino PT, J Natl Cancer Inst 2007 99 15 1171 1177 10.1093/jnci/djm060 17652279 (Pubitemid 47233067)
14. How bad is categorization? Weinberg CR, Epidemiology 1995 6 4 345 347 10.1097/00001648-199507000-00002 7548338
15. Prospective study of sex hormone levels and risk of prostate cancer. Gann PH, Hennekens CH, Ma J, Longcope C, Stampfer MJ, J Natl Cancer Inst 1996 88 16 1118 1126 10.1093/jnci/88.16.1118 8757191 (Pubitemid 26274606)
16. Categorizing BMI may lead to biased results in studies investigating in-hospital mortality after isolated CABG. Filardo G, Hamilton C, Hamman B, Ng HK, Grayburn P, J Clin Epidemiol 2007 60 11 1132 1139 10.1016/j.jclinepi.2007. 01.008 17938055 (Pubitemid 47554684)
17. Prostate-specific antigen at or before age 50 as a predictor of advanced prostate cancer diagnosed up to 25 years later: a case-control study. Ulmert D, Cronin AM, Bjork T, O'Brien MP, Scardino PT, Eastham JA, Becker C, Berglund G, Vickers AJ, Lilja H, BMC Med 2008 15 6 6
18. A panel of kallikrein marker predicts prostate cancer in a large, population-based cohort followed for 15 years without screening. Vickers AJ, Gupta A, Savage CJ, Pettersson K, Dhalin A, Bjartell A, Manjer J, Scardino PT, Ulmert D, Lilja H, Cancer Epidemiol Biomarkers Prev 2011 20 2 255 61 10.1158/1055-9965.EPI-10-1003 21148123
19. Building multivariable regression models with continuous covariates in clinical epidemiology-with an emphasis on fractional polynomials. Royston P, Sauerbrei W, Methods Inf Med 2005 44 4 561 571 16342923 (Pubitemid 41345381)
20. The surgical learning curve for laparoscopic radical prostatectomy: a retrospective cohort study. Vickers AJ, Savage CJ, Hruza M, Tuerk I, Koenig P, Martinez-Pineiro L, Janetschek G, Guillonneau B, Lancet Oncol 2009 10 5 475 480 10.1016/S1470-2045(09)70079-8 19342300