Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin

International Journal of Oncology

Volumn 45, Issue 4, 2014, Pages 1735-1741

  Liu, Yong Bo ^a   Gao, Xiaohua ^a   Deeb, Dorah ^a   Brigolin, Chris ^a   Zhang, Yiguan ^a   Shaw, Jiajiu ^a   Pindolia, Kirit ^a   Gautam, Subhash C ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Apoptosis; Pristimerin; Prostate cancer; Proteasome; Survivin; Ubiquitin

Indexed keywords

LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PRISTIMERIN; PROTEASOME; PROTEIN BCL 2; SURVIVIN; UBIQUITIN; ATP DEPENDENT 26S PROTEASE; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LNCAP CELL LINE; MALE; MTS ASSAY; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN INDUCTION; TREATMENT OUTCOME; WESTERN BLOTTING; CELL CYCLE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; PROSTATIC NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; TRITERPENES; UBIQUITIN;

EID: 84907465384     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2561     Document Type: Article

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