The Z mutation alters the global structural dynamics of α1-antitrypsin

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Hughes, Victoria A ^a   Meklemburg, Robert ^b   Bottomley, Stephen P ^a   Wintrode, Patrick L ^b  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; GLUTAMINE; LYSINE; PEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEUTERIUM HYDROGEN EXCHANGE; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; MUTATIONAL ANALYSIS; PROTEIN POLYMERIZATION; PROTEIN SECONDARY STRUCTURE; RESIDUE ANALYSIS; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; THERMODYNAMICS; THERMOSTABILITY; CHEMISTRY; GENETICS; HUMAN; KINETICS; MOLECULAR GENETICS; MUTATION; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; TIME;

ALPHA 1-ANTITRYPSIN; AMINO ACID SEQUENCE; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTATION; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; PEPTIDES; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 84907452502     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102617     Document Type: Article

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