A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

Malaria Journal

Volumn 13, Issue 1, 2014, Pages

  Fletcher, Sabine ^a   Avery, Vicky M ^a  

^a GRIFFITH UNIVERSITY   (Australia)

Author keywords

Anti malarial compounds; Coenzyme A synthesis; HTS drug discovery; Malaria; Medicines for malaria venture (MMV) malaria box; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; COENZYME A;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME SYNTHESIS; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC50; MICROSCOPY; NONHUMAN; PHENOTYPE; PLASMODIUM FALCIPARUM; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG DEVELOPMENT; DRUG EFFECTS; DRUG SCREENING; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; METABOLISM; PROCEDURES;

ANTIMALARIALS; CELL LINE; COENZYME A; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; METABOLIC NETWORKS AND PATHWAYS; PLASMODIUM FALCIPARUM;

EID: 84907429588     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-13-343     Document Type: Article

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