Polymorphism of the FTO gene influences body weight in children with type 1 diabetes without severe obesity

International Journal of Endocrinology

Volumn 2014, Issue , 2014, Pages

  Łuczyński, Włodzimierz ^a   Fendler, Wojciech ^b   Ramatowska, Anna ^c   Szypowska, Agnieszka ^c   Szadkowska, Agnieszka ^b   Młynarski, Wojciech ^b   Chumiecki, Miron ^d   Jarosz Chobot, Przemysława ^d   Chrzanowska, Joanna ^e   Noczyńska, Anna ^e   Brandt, Agnieszka ^f   Mys̈liwiec, Małgorzata ^f   Głowińska Olszewska, Barbara ^a   Bernatowicz, Paweł ^a   Kowalczuk, Oksana ^a   Bossowski, Artur ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

^d MEDICAL UNIVERSITY OF SILESIA   (Poland)

^e WROCLAW MEDICAL UNIVERSITY   (Poland)

^f MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C;

ADOLESCENT; ALLELE; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CD36 GENE; CHILD; CHILD HEALTH CARE; DISEASE SEVERITY; FASN GENE; FEMALE; FTO GENE; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEMOGLOBIN BLOOD LEVEL; HETEROZYGOTE; HUMAN; INSIG2 GENE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; IRT1 GENE; MAF GENE; MAJOR CLINICAL STUDY; MALE; MC4R GENE; METABOLIC REGULATION; NPC1 GENE; OBESITY; PTER GENE; SEX DIFFERENCE; SIRT1 GENE;

EID: 84907419835     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2014/630712     Document Type: Article

References (18)

1. M. Chrzanowska, S. Koziel, and S. J. Ulijaszek, "Changes in BMI and the prevalence of overweight and obesity in children and adolescents in Cracow, Poland, 1971-2000," Economics & Human Biology, vol. 5, no. 3, pp. 370-378, 2007.
2. T. M. Frayling, N. J. Timpson, M. N. Weedon et al., "A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity," Science, vol. 316, no. 5826, pp. 889-894, 2007.
3. J. Cecil, M. Dalton, G. Finlayson, J. Blundell, M. Hetherington, and C. Palmer, "Obesity and eating behaviour in children and adolescents: contribution of common gene polymorphisms," International Review of Psychiatry, vol. 24, no. 3, pp. 200-210, 2012.
4. D. Malzahn, M. Müller-Nurasyid, I. M. Heid, H. E. Wichmann, The KORA Study Group6, and H. Bickeböller, "Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R," European Journal of Human Genetics, 2014
5. C. Steigleder-Schweiger, B. Rami-Merhar, T. Waldhör et al., "Prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes in Austria," European Journal of Pediatrics, vol. 171, no. 8, pp. 1193-1202, 2012.
6. S. Krishnan, D. A. Fields, K. C. Copeland, P. R. Blackett, M. P. Anderson, and A. W. Gardner, "Sex differences in cardiovascular disease risk in adolescents with type 1 diabetes," Gender Medicine, vol. 9, no. 4, pp. 251-258, 2012.
7. H. B. Mortensen, P. Hougaard, P. Swift et al., "New definition for the partial remission period in children and adolescents with type 1 diabetes," Diabetes Care, vol. 32, no. 8, pp. 1384-1390, 2009.
8. Z. Kułaga, M. Litwin, M. Tkaczyk et al., "Polish 2010 growth references for school-aged children and adolescents," European Journal of Pediatrics, vol. 170, no. 5, pp. 599-609, 2011.
9. J. M. Bland and D. G. Altman, "Statistical methods for assessing agreement between two methods of clinical measurement," The Lancet, vol. 1, no. 8476, pp. 307-310, 1986.
10. B. Pyrzak, A. Wisniewska, A. Majcher, A. Tysarowski, and U. Demkow, "Relation of fat-mass and obesity-associated gene polymorphism to fat mass content and body mass index in obese children," Advances in Experimental Medicine and Biology, vol. 756, pp. 255-262, 2013.
11. W. Luczynski, G. Zalewski, and A. Bossowski, "The association of the FTO rs9939609 polymorphism with obesity and metabolic risk factors for cardiovascular diseases in polish children," Journal of Physiology and Pharmacology, vol. 63, no. 3, pp. 241-248, 2012.
12. S. F. Field, J. M. M. Howson, N. M. Walker, D. B. Dunger, and J. A. Todd, "Analysis of the obesity gene FTO in 14,803 type 1 diabetes cases and controls," Diabetologia, vol. 50, no. 10, pp. 2218-2220, 2007.
13. C. Winkler, J. Raab, H. Grallert, and A. Ziegler, "Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes," PloS ONE, vol. 7, no. 4, Article ID e35410, 2012.
14. H. F. Gu, A. Alvarsson, and K. Brismar, "The common FTO genetic polymorphism rs9939609 is associated with increased BMI in type 1 diabetes but not with diabetic nephropathy," Biomarker Insights, vol. 5, pp. 29-32, 2010.
15. J. Zhao, J. P. Bradfield, M. Li et al., "The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI," Obesity, vol. 17, no. 12, pp. 2254-2257, 2009.
16. K. O. Schwab, J. Doerfer, W. Marg, E. Schober, and R. W. Holl, "Characterization of 33 488 children and adolescents with type 1 diabetes based on the gender-specific increase of cardiovascular risk factors," Pediatric Diabetes, vol. 11, no. 5, pp. 357-363, 2010.
17. T. R. Nansel, J. Tse, D. L. Haynie, S. N. Mehta, and L. M. B. Laffel, "Disordered eating behaviors are associated with poorer diet quality in adolescents with type 1 diabetes," Journal of the Academy of Nutrition and Dietetics, vol. 112, no. 11, pp. 1810-1814, 2012.
18. A. L. P. Sands, L. A. Higgins, S. N. Mehta, T. R. Nansel, L. M. Lipsky, and L. M. B. Laffel, "Associations of youth and parent weight status with reported versus predicted daily energy intake and hemoglobin A1c in youth with type 1 diabetes mellitus," Journal of Diabetes Science and Technology, vol. 7, no. 1, pp. 263-270, 2013.