A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

Molecular Systems Biology

Volumn 10, Issue 8, 2014, Pages

  Yizhak, Keren ^a   Le Dévédec, Sylvia E ^b   Rogkoti, Vasiliki Maria ^b   Baenke, Franziska ^c   De Boer, Vincent C ^d   Frezza, Christian ^e   Schulze, Almut ^c   Van De Water, Bob ^b   Ruppin, Eytan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b LEIDEN UNIVERSITY   (Netherlands)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

cancer cell migration; cellular metabolism; genome scale metabolic modeling

Indexed keywords

ADENOSINE TRIPHOSPHATE; LACTIC ACID; SMALL INTERFERING RNA;

ARTICLE; BIOENERGY; BIOMASS PRODUCTION; BREAST CANCER CELL LINE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; GENE SILENCING; GENE TARGETING; GENOME SCALE METABOLIC MODEL; GLYCOLYSIS; HUMAN; HUMAN CELL; LUNG CANCER CELL LINE; METABOLIC PARAMETERS; PREDICTION; PRIORITY JOURNAL; STOICHIOMETRY; BIOLOGICAL MODEL; BIOLOGY; BREAST TUMOR; CELL MOTION; GENETICS; LUNG TUMOR; METABOLISM; PROCEDURES; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; GENE SILENCING; GLYCOLYSIS; HUMANS; LACTIC ACID; LUNG NEOPLASMS; MODELS, BIOLOGICAL; RNA, SMALL INTERFERING;

EID: 84907379295     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20134993     Document Type: Article

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